4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Anneken JH et al. | MDMA increases glutamate release and reduces parvalbumin-positive GABAergic cells in the dorsal hippocampus of the rat: role of cyclooxygenase. | 2013 | J Neuroimmune Pharmacol | pmid:23179355 |
Egashira N et al. | Effects of mood stabilizers on marble-burying behavior in mice: involvement of GABAergic system. | 2013 | Psychopharmacology (Berl.) | pmid:23086022 |
Han B et al. | Quantitative LC-MS/MS analysis of arachidonoyl amino acids in mouse brain with treatment of FAAH inhibitor. | 2013 | Anal. Biochem. | pmid:23044255 |
Rajak H et al. | Novel limonene and citral based 2,5-disubstituted-1,3,4-oxadiazoles: a natural product coupled approach to semicarbazones for antiepileptic activity. | 2013 | Bioorg. Med. Chem. Lett. | pmid:23265873 |
Shamsi Meymandi M and Keyhanfar F | Relative potency of pregabalin, gabapentin, and morphine in a mouse model of visceral pain. | 2013 | Can J Anaesth | pmid:23132044 |
Siebel AM et al. | Antiepileptic drugs prevent changes in adenosine deamination during acute seizure episodes in adult zebrafish. | 2013 | Pharmacol. Biochem. Behav. | pmid:23287800 |
Vanelderen P et al. | Effects of chronic administration of amitriptyline, gabapentin and minocycline on spinal brain-derived neurotrophic factor expression and neuropathic pain behavior in a rat chronic constriction injury model. | 2013 Mar-Apr | Reg Anesth Pain Med | pmid:23337936 |
Gassel M et al. | The novel isoxazoline ectoparasiticide fluralaner: selective inhibition of arthropod γ-aminobutyric acid- and L-glutamate-gated chloride channels and insecticidal/acaricidal activity. | 2014 | Insect Biochem. Mol. Biol. | pmid:24365472 |