4-aminobutyric acid

4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.

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Introduction

To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-aminobutyric acid?

4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid

MeSH term MeSH ID Detail
Meige Syndrome D008538 1 associated lipids
Carcinoma, Acinar Cell D018267 1 associated lipids
Neuroectodermal Tumors, Primitive D018242 1 associated lipids
alpha-Mannosidosis D008363 1 associated lipids
Hiccup D006606 1 associated lipids
Chorea D002819 1 associated lipids
Congenital Disorders of Glycosylation D018981 1 associated lipids
Tongue, Fissured D014063 1 associated lipids
Tuberous Sclerosis D014402 2 associated lipids
Renal Aminoacidurias D000608 2 associated lipids
Alcohol Amnestic Disorder D000425 2 associated lipids
Akathisia, Drug-Induced D017109 2 associated lipids
Pituitary Diseases D010900 2 associated lipids
Wernicke Encephalopathy D014899 2 associated lipids
Self Mutilation D012652 2 associated lipids
Restless Legs Syndrome D012148 2 associated lipids
Ocular Motility Disorders D015835 2 associated lipids
Primary Ovarian Insufficiency D016649 2 associated lipids
Prader-Willi Syndrome D011218 2 associated lipids
Catatonia D002389 2 associated lipids
Dysarthria D004401 2 associated lipids
Diplopia D004172 2 associated lipids
Neck Pain D019547 2 associated lipids
Epilepsy, Tonic-Clonic D004830 2 associated lipids
Low Back Pain D017116 2 associated lipids
Hypoparathyroidism D007011 2 associated lipids
Psychoses, Alcoholic D011604 2 associated lipids
Earache D004433 2 associated lipids
Esophageal and Gastric Varices D004932 2 associated lipids
Gyrate Atrophy D015799 2 associated lipids
Olivopontocerebellar Atrophies D009849 2 associated lipids
Retinal Artery Occlusion D015356 2 associated lipids
Hamartoma D006222 2 associated lipids
Melkersson-Rosenthal Syndrome D008556 2 associated lipids
Hypokinesia D018476 2 associated lipids
Amnesia, Retrograde D000648 2 associated lipids
Cocaine-Related Disorders D019970 3 associated lipids
Myoclonus D009207 3 associated lipids
Fetal Hypoxia D005311 3 associated lipids
Tuberculosis, Meningeal D014390 3 associated lipids
Common Bile Duct Diseases D003137 3 associated lipids
Perceptual Disorders D010468 3 associated lipids
Encephalitis, Viral D018792 3 associated lipids
Spasms, Infantile D013036 3 associated lipids
Hyperphagia D006963 3 associated lipids
Cestode Infections D002590 3 associated lipids
Hypotension, Orthostatic D007024 3 associated lipids
Herpes Simplex D006561 3 associated lipids
Tourette Syndrome D005879 3 associated lipids
Polyneuropathies D011115 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 4-aminobutyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 4-aminobutyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 4-aminobutyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-aminobutyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-aminobutyric acid

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Authors Title Published Journal PubMed Link
Miles R Neurobiology. A homeostatic switch. 1999 Nature pmid:9930694
Rivera C et al. The K+/Cl- co-transporter KCC2 renders GABA hyperpolarizing during neuronal maturation. 1999 Nature pmid:9930699
Rhee JS et al. Calcium channels in the GABAergic presynaptic nerve terminals projecting to meynert neurons of the rat. 1999 J. Neurochem. pmid:9930756
Pombal MA et al. Cholinergic and GABAergic neuronal elements in the pineal organ of lampreys, and tract-tracing observations of differential connections of pinealofugal neurons. 1999 Cell Tissue Res. pmid:9931367
Martin R et al. Cognitive effects of topiramate, gabapentin, and lamotrigine in healthy young adults. 1999 Neurology pmid:9932951
Mameli O et al. Epileptic discharge of cortical, subcortical and spinal neurons in penicillin induced experimental epilepsy. 1999 Arch Ital Biol pmid:9934432
Galenko-IaroshevskiÄ­ PA et al. [Effect of the gamma-aminobutyric acid derivative, TZ-50-2, on the systemic and cardiac hemodynamics, and the size of myocardial necrosis area]. 1998 Biull Eksp Biol Med pmid:9934514
Frye MA et al. Possible gabapentin-induced thyroiditis. 1999 J Clin Psychopharmacol pmid:9934948
Fukuda A et al. Simultaneous optical imaging of intracellular Cl- in neurons in different layers of rat neocortical slices: advantages and limitations. 1998 Neurosci. Res. pmid:9950064
Morrison SF et al. GABA-mediated inhibition of raphe pallidus neurons regulates sympathetic outflow to brown adipose tissue. 1999 Am. J. Physiol. pmid:9950904