4-aminobutyric acid

4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.

Cross Reference

Introduction

To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-aminobutyric acid?

4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid

MeSH term MeSH ID Detail
Kidney Neoplasms D007680 29 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Neuralgia D009437 28 associated lipids
Insulinoma D007340 28 associated lipids
Alcoholism D000437 27 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Brain Diseases D001927 27 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Hyperemia D006940 25 associated lipids
Cerebrovascular Disorders D002561 25 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Stomach Neoplasms D013274 24 associated lipids
Medulloblastoma D008527 22 associated lipids
Hyperglycemia D006943 21 associated lipids
Wounds and Injuries D014947 20 associated lipids
Ataxia D001259 20 associated lipids
Brain Edema D001929 20 associated lipids
Hypothermia D007035 19 associated lipids
Cough D003371 19 associated lipids
Down Syndrome D004314 18 associated lipids
Ischemia D007511 18 associated lipids
Parkinson Disease, Secondary D010302 17 associated lipids
Liver Cirrhosis, Alcoholic D008104 17 associated lipids
Hypertrophy D006984 16 associated lipids
Ventricular Fibrillation D014693 16 associated lipids
Tremor D014202 15 associated lipids
Encephalitis D004660 15 associated lipids
Fetal Resorption D005327 15 associated lipids
Dyskinesia, Drug-Induced D004409 15 associated lipids
Alcoholic Intoxication D000435 15 associated lipids
Reye Syndrome D012202 14 associated lipids
Sarcoma, Experimental D012513 13 associated lipids
Multiple Sclerosis D009103 13 associated lipids
Bradycardia D001919 13 associated lipids
Heart Arrest D006323 13 associated lipids
Cerebral Hemorrhage D002543 13 associated lipids
Ketosis D007662 13 associated lipids
Intellectual Disability D008607 13 associated lipids
Pain, Postoperative D010149 13 associated lipids
Hyperthyroidism D006980 12 associated lipids
Death, Sudden D003645 12 associated lipids
Amnesia D000647 12 associated lipids
Hypocalcemia D006996 12 associated lipids
Retinoblastoma D012175 12 associated lipids
Duodenal Ulcer D004381 12 associated lipids
Hypertension, Portal D006975 12 associated lipids
Amyotrophic Lateral Sclerosis D000690 11 associated lipids
Exanthema D005076 11 associated lipids
Meningioma D008579 11 associated lipids
Hyperkinesis D006948 11 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 4-aminobutyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 4-aminobutyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 4-aminobutyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-aminobutyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-aminobutyric acid

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Per page 10 20 50 100 | Total 40318
Authors Title Published Journal PubMed Link
Albuquerque EX et al. Neuronal nicotinic receptors modulate synaptic function in the hippocampus and are sensitive to blockade by the convulsant strychnine and by the anti-Parkinson drug amantadine. 1998 Toxicol. Lett. pmid:10022256
Pitkänen A et al. Effects of vigabatrin treatment on status epilepticus-induced neuronal damage and mossy fiber sprouting in the rat hippocampus. 1999 Epilepsy Res. pmid:10022367
Pérez-Cerdá F et al. Postnatal development of perisomatic GABAergic axon terminals on neurons projecting from area 17 to area 18 of the cat visual cortex. 1999 Jan-Feb Vis. Neurosci. pmid:10022476
Osborne NN Memantine reduces alterations to the mammalian retina, in situ, induced by ischemia. 1999 Jan-Feb Vis. Neurosci. pmid:10022477
Napper GA et al. Reduced glutamate uptake by retinal glial cells under ischemic/hypoxic conditions. 1999 Jan-Feb Vis. Neurosci. pmid:10022486
Nelson R et al. Distribution of GABA(C)-like responses among acutely dissociated rat retinal neurons. 1999 Jan-Feb Vis. Neurosci. pmid:10022489
Reiriz J et al. Bone morphogenetic protein-2 promotes dissociated effects on the number and differentiation of cultured ventral mesencephalic dopaminergic neurons. 1999 J. Neurobiol. pmid:10022564
Torrealba F and Müller C Ultrastructure of glutamate and GABA immunoreactive axon terminals of the rat nucleus tractus solitarius, with a note on infralimbic cortex afferents. 1999 Brain Res. pmid:10023027
Langan Y et al. An audit of the perceived efficacy and tolerability of gabapentin therapy in an out-patient cohort with chronic epilepsy. 1999 Eur. Neurol. pmid:10023116
Blanchet F et al. Role of arachidonic acid in the regulation of the NMDA-evoked release of acetylcholine in striatal compartments. 1999 Synapse pmid:10024011