4-aminobutyric acid
4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
Cross Reference
Introduction
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 4-aminobutyric acid?
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
PubChem Associated disorders and diseases
What pathways are associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 4-aminobutyric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with 4-aminobutyric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 4-aminobutyric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Redburn DA | Relationship between synaptosomal uptake and release of [14C]gaba, [14C]diaminobutyric acid and [14C]beta-alanine. | 1978 | J. Neurochem. | pmid:100577 |
| Brennan MJ and Cantrill RC | The effect of DABA and beta-alanine on the efflux of [3H] GABA from preloaded rat brain synaptosomes. | 1978 | J. Neurochem. | pmid:100581 |
| Roberts E | Some thoughts about GABA and the basal ganglia. | 1976 | Res Publ Assoc Res Nerv Ment Dis | pmid:1005901 |
| Ribak CE et al. | Immunocytochemical localization of glutamate decarboxylase in the substantia nigra of the rat. | 1976 | Res Publ Assoc Res Nerv Ment Dis | pmid:1005902 |
| Ye JH et al. | Cocaine and lidocaine have additive inhibitory effects on the GABAA current of acutely dissociated hippocampal pyramidal neurons. | 1999 | Brain Res. | pmid:10064784 |
| Gernert M et al. | Alterations in spontaneous single unit activity of striatal subdivisions during ontogenesis in mutant dystonic hamsters. | 1999 | Brain Res. | pmid:10064814 |
| Biggs KR and Prosser RA | Neuropeptide Y blocks GABAB-induced phase-shifts of the suprachiasmatic circadian clock in vitro. | 1999 | Brain Res. | pmid:10064833 |
| Bailey CD et al. | Neurosteroid modulation of the GABAA receptor in the developing guinea pig cerebral cortex. | 1999 | Brain Res. Dev. Brain Res. | pmid:10064870 |
| Hupé JM et al. | Spatial and temporal parameters of cortical inactivation by GABA. | 1999 | J. Neurosci. Methods | pmid:10065982 |
| Maitra R and Reynolds JN | Modulation of GABA(A) receptor function by neuroactive steroids: evidence for heterogeneity of steroid sensitivity of recombinant GABA(A) receptor isoforms. | 1998 | Can. J. Physiol. Pharmacol. | pmid:10066142 |