4-aminobutyric acid
4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
Cross Reference
Introduction
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 4-aminobutyric acid?
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
PubChem Associated disorders and diseases
What pathways are associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 4-aminobutyric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 4-aminobutyric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 4-aminobutyric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Bondarenko TI et al. | [Intensity of label incorporation from [1,4-14C]putrescine into homocarnosine in the brain of rats of various ages]. | 1986 Sep-Oct | Ukr. Biokhim. Zh. | pmid:3775887 |
| Rozanov VA | [Characteristics of the glutamate decarboxylase reaction in homogenates of various regions of the rat brain]. | 1987 Sep-Oct | Ukr. Biokhim. Zh. | pmid:3686692 |
| BabiÄchuk GA et al. | [Effect of hypothermia on reuptake of neuromediators by synaptosomes]. | 1985 Mar-Apr | Ukr. Biokhim. Zh. | pmid:4002372 |
| Fomenko AI et al. | [The functional characteristics of the inhibitory mediator systems in the brain synaptosomes of PP vitamin-deficient rats]. | 1992 Nov-Dec | Ukr. Biokhim. Zh. | pmid:1488805 |
| Agaev TM | [GABA-transaminase activity in the dog brain visual analyzer following light deprivation during ontogenesis]. | 1979 Jan-Feb | Ukr. Biokhim. Zh. | pmid:425136 |
| Bondarenko TI and Makletsova MG | [Content of homocarnosine, gamma-amino butyric acid and histidine in brain tissue of different age normal rabbits and under hyperoxia]. | 1979 Mar-Apr | Ukr. Biokhim. Zh. | pmid:452127 |
| Shchortanova TKh | [Content of dicarboxylic acids and GABA in normal suslik brain and under the effect of oxygen at higher pressure]. | 1978 Jul-Aug | Ukr. Biokhim. Zh. | pmid:556358 |
| Rozanov VA | [[14C] GABA and [14C]GABA-pantoyl metabolism in mice]. | 1979 Nov-Dec | Ukr. Biokhim. Zh. | pmid:543029 |
| Emirbekov EZ and Ismanlov IA | [Effect of hypothermia on the ammonia-glutamine-glutamic acid system in ground squirrels after hibernation]. | 1979 Nov-Dec | Ukr. Biokhim. Zh. | pmid:543034 |
| Bondarenko TI et al. | [Metabolism of homocarnosine and gamma-amino butyric acid in different regions of rat brain under hyperoxia]. | 1978 Sep-Oct | Ukr. Biokhim. Zh. | pmid:726092 |
| Nechaeva GA and Shelepina EP | [Effect of norepinephrine, GABA and cysteine on the complex of alkaline ribonuclease with its protein inhibitor]. | 1979 Sep-Oct | Ukr. Biokhim. Zh. | pmid:42177 |
| Rozanov VA and ReÄtarova TE | [Effect of vitamin B3-active compounds on the content of free and combined gamma-aminobutyric acid and glutamic acid in the brain of mice]. | 1983 Nov-Dec | Ukr. Biokhim. Zh. | pmid:6140785 |
| Lisniak IA | [Monoaminodicarboxylic acids and enzymes of their metabolism in animal tissues in the process of tumor growth]. | 1981 May-Jun | Ukr. Biokhim. Zh. | pmid:6114585 |
| Rozanov VA | [Seasonal changes in the gamma-aminobutyric acid system of the mouse brain]. | 1982 | Ukr. Biokhim. Zh. | pmid:6120593 |
| Snisar' IA and Orekhov VS | [Content of components GABA metabolism in the brain of cats and rats]. | 1982 Sep-Oct | Ukr. Biokhim. Zh. | pmid:6127826 |
| Fomenko AI et al. | [Participation of benzodiazepine receptors in the mechanism of action of nicotinamide in nerve cells]. | 1994 Jul-Aug | Ukr. Biokhim. Zh. | pmid:7879292 |
| Gerasimiak GR et al. | [Effect of bis(n-tributyltin)-oxide on the brain GABA-ergic system in vitro]. | 1994 Mar-Apr | Ukr. Biokhim. Zh. | pmid:7998344 |
| Donchenko GV et al. | [Effect of nicotinamide on the uptake and release of serotonin and GABA by cerebral cortex synaptosomes in rats with diabetes induced by streptozotocin]. | 1995 Jan-Feb | Ukr. Biokhim. Zh. | pmid:8588246 |
| Gordienko EA and Zhubrikova LA | [Ontogenic differences of glutamate decarboxylase, GABA-aminotransferase, monoamine oxidase activities of cerebral cortex mitochondria and hypothalamic cerebral area]. | 1980 Jul-Aug | Ukr. Biokhim. Zh. | pmid:7210203 |
| Kononenko VIa and Mishunina TM | [Effect of hydrocortisone on gamma-aminobutyric acid content and glutamate decarboxylase activity in various areas of the rat brain]. | 1982 | Ukr. Biokhim. Zh. | pmid:7058550 |
| Andreev BV et al. | [Effect of emotional-pain stress on the activity of the gamma-aminobutyric acid system]. | 1983 Nov-Dec | Ukr. Biokhim. Zh. | pmid:6686357 |
| Fomenko AI et al. | [Interaction of GABA-ergic component of NAD with benzodiazepine receptors during epileptogenesis]. | 1997 Mar-Apr | Ukr. Biokhim. Zh. | pmid:9463239 |
| Rozanov AIa et al. | [Metabolism and catabolism to CO2 of [14C] gamma-aminobutyric acid conjugates with pyridoxal phosphate, nicotinate and biotin]. | 1993 Jul-Aug | Ukr. Biokhim. Zh. | pmid:8284828 |
| Kuchmerovs'ka TM | [Neurotrophic action of nicotinamide and nicotinoyl-GABA in rat brain in experimental Parkinsonism]. | 1998 Nov-Dec | Ukr. Biokhim. Zh. | pmid:10402661 |
| Menzikov SA and Menzikova OV | [Effect of gamma-aminobutyric acid on Mg2+-ATPase of brain microsomes of the fish Abramis brama L]. | 1999 Jan-Feb | Ukr Biokhim Zh (1999) | pmid:10458003 |
| Emirbekova AA | [Effect of hypothermia and hyperoxia on the ammonia-glutamic acid system in the brain of rats]. | 1976 Apr-Jun | Ukr Biokhim Zh | pmid:960239 |
| Rozanov VA et al. | [Intake dynamics of GABA and its pantoate derivative in mice brain areas]. | 1977 Nov-Dec | Ukr Biokhim Zh | pmid:929708 |
| Agaev TM et al. | [Dynamics of changes in the level of GABA in various sections of the cerebral cortex and cerebellum of dogs during postnatal ontogenesis]. | 1975 Jan-Feb | Ukr Biokhim Zh | pmid:1202697 |
| Agaev TM and Belik IaV | [Concentration of dicarboxylic amino acids and GABA in the structures of the cerebral visual analyzer and retina of dogs during postnatal ontogenesis]. | 1977 Jan-Feb | Ukr Biokhim Zh | pmid:867525 |
| Agaev TM and Ifraimova ZN | [Age and changes in the concentration of dicarboxylic amino acids and GABA in different portions of the dog cerebral cortex and cerebellum]. | 1977 Mar-Apr | Ukr Biokhim Zh | pmid:867535 |
| Korniushenko NP and Zriakov OM | [Effect of estradiol on content of monoamines and acetylcholine in rat hypothalamus]. | 1977 Jul-Aug | Ukr Biokhim Zh | pmid:898319 |
| Safarov MI et al. | [Postnatal changes of gamma-aminobutryric acid in rat brain with acute benzene poisoning]. | 1977 Jul-Aug | Ukr Biokhim Zh | pmid:898322 |
| Shchipakina TG and Budantsev AIu | [Glutamate dehydrogenase activity in the structures of the rabbit brain limbic system]. | 1976 Apr-Jun | Ukr Biokhim Zh | pmid:822551 |
| Akshabaeva KA | [The effect of aminazine and imizine on the metabolism of dicarboxylic amino acids and their derivatives (glutamine and gamma-aminobutyric acid) in the cat brain]. | 1972 | Ukr Biokhim Zh | pmid:4661064 |
| Agaev TM and Belik IaV | [Change in the gamma-aminobutyric acid content in various structures of the cerebral visual analyzer and in the retina of the dog in postnatal ontogeny]. | 1974 Nov-Dec | Ukr Biokhim Zh | pmid:4450262 |
| Gerlach J | [Tardive dyskinesias. Epidemiology and physiopathology]. | 1987 | Ugeskr. Laeg. | pmid:2885954 |
| Gulmann NC | [GABA system in the brain. Possible clinical and pharmacological aspects]. | 1978 | Ugeskr. Laeg. | pmid:151363 |
| Magelund CG and Mørck HI | [Gynecomastia during benzodiazepine abuse]. | 1979 | Ugeskr. Laeg. | pmid:531955 |
| Kamp-Jensen M and Werner MU | [Gabapentin--yet another antiepileptic agent for the treatment of neuropathic pain?]. | 2001 | Ugeskr. Laeg. | pmid:11218787 |
| Ozbek Z et al. | Neuroprotective Effect of Genistein in Peripheral Nerve Injury. | 2017 | Turk Neurosurg | pmid:27759874 |
| Bowery NG | GABA transporter protein cloned from rat brain. | 1990 | Trends Pharmacol. Sci. | pmid:2267667 |
| Phillis JW and O'Regan MH | Benzodiazepine interaction with adenosine systems explains some anomalies in GABA hypothesis. | 1988 | Trends Pharmacol. Sci. | pmid:2854669 |
| Chapman RW et al. | GABAB receptors in the lung. | 1993 | Trends Pharmacol. Sci. | pmid:8382886 |
| Upton N | Mechanisms of action of new antiepileptic drugs: rational design and serendipitous findings. | 1994 | Trends Pharmacol. Sci. | pmid:7886818 |
| Malcangio M and Bowery NG | GABA and its receptors in the spinal cord. | 1996 | Trends Pharmacol. Sci. | pmid:9014500 |
| Fredholm BB and Svenningsson P | Striatal adenosine A2A receptors--where are they? What do they do? | 1998 | Trends Pharmacol. Sci. | pmid:9550940 |
| Bonanno G and Raiteri M | Multiple GABAB receptors. | 1993 | Trends Pharmacol. Sci. | pmid:8105595 |
| Soghomonian JJ and Martin DL | Two isoforms of glutamate decarboxylase: why? | 1998 | Trends Pharmacol. Sci. | pmid:9871412 |
| Chizh BA et al. | The race to control pain: more participants, more targets. | 1999 | Trends Pharmacol. Sci. | pmid:10462755 |
| Guidotti A et al. | Characterization of the action of antipsychotic subtypes on valproate-induced chromatin remodeling. | 2009 | Trends Pharmacol. Sci. | pmid:19110320 |