4-aminobutyric acid

4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.

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Introduction

To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-aminobutyric acid?

4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid

MeSH term MeSH ID Detail
Confusion D003221 4 associated lipids
Constriction, Pathologic D003251 8 associated lipids
Coronary Disease D003327 70 associated lipids
Cough D003371 19 associated lipids
Cranial Nerve Diseases D003389 1 associated lipids
Cushing Syndrome D003480 5 associated lipids
Dandy-Walker Syndrome D003616 1 associated lipids
Death, Sudden D003645 12 associated lipids
Decerebrate State D003655 7 associated lipids
Drug Eruptions D003875 30 associated lipids
Diabetes Insipidus D003919 5 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Diplopia D004172 2 associated lipids
Down Syndrome D004314 18 associated lipids
Duodenal Ulcer D004381 12 associated lipids
Dysarthria D004401 2 associated lipids
Dyskinesia, Drug-Induced D004409 15 associated lipids
Dystonia D004421 3 associated lipids
Dystonia Musculorum Deformans D004422 1 associated lipids
Earache D004433 2 associated lipids
Encephalitis D004660 15 associated lipids
Encephalomyelitis, Venezuelan Equine D004685 1 associated lipids
Epilepsy D004827 35 associated lipids
Epilepsies, Partial D004828 3 associated lipids
Epilepsy, Tonic-Clonic D004830 2 associated lipids
Epilepsy, Absence D004832 5 associated lipids
Epilepsy, Temporal Lobe D004833 4 associated lipids
Epilepsy, Post-Traumatic D004834 1 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Esophageal and Gastric Varices D004932 2 associated lipids
Esotropia D004948 1 associated lipids
Exanthema D005076 11 associated lipids
Fetal Hypoxia D005311 3 associated lipids
Fetal Diseases D005315 8 associated lipids
Fetal Growth Retardation D005317 9 associated lipids
Fetal Resorption D005327 15 associated lipids
Fever D005334 35 associated lipids
Filariasis D005368 6 associated lipids
Gigantism D005877 1 associated lipids
Tourette Syndrome D005879 3 associated lipids
Glioma D005910 112 associated lipids
Pantothenate Kinase-Associated Neurodegeneration D006211 1 associated lipids
Hamartoma D006222 2 associated lipids
Heart Arrest D006323 13 associated lipids
Hemolysis D006461 131 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Hepatic Encephalopathy D006501 9 associated lipids
Hepatitis A D006506 8 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 4-aminobutyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 4-aminobutyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 4-aminobutyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-aminobutyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-aminobutyric acid

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Per page 10 20 50 100 | Total 40318
Authors Title Published Journal PubMed Link
Torrealba F and Müller C Ultrastructure of glutamate and GABA immunoreactive axon terminals of the rat nucleus tractus solitarius, with a note on infralimbic cortex afferents. 1999 Brain Res. pmid:10023027
Reiriz J et al. Bone morphogenetic protein-2 promotes dissociated effects on the number and differentiation of cultured ventral mesencephalic dopaminergic neurons. 1999 J. Neurobiol. pmid:10022564
Nelson R et al. Distribution of GABA(C)-like responses among acutely dissociated rat retinal neurons. 1999 Jan-Feb Vis. Neurosci. pmid:10022489
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Wenk M et al. Partial separation of synaptosomes accumulating 4-aminobutyrate or glutamate by zonal centrifugation on a discontinuous sucrose gradient. 1976 Hoppe-Seyler's Z. Physiol. Chem. pmid:1002126
Fisher SK and Davies WE 4-Aminobutyric acid in the mammalian cochlear nucleus. 1976 Biochem. Soc. Trans. pmid:1001676
Mitchell JF Release of physiologically active amino acids from intact brain and spinal-cord preparations. 1976 Biochem. Soc. Trans. pmid:1001605
Kovalev GV et al. [Analysis of the ganglionic action of gamma-aminobutyric acid and its derivatives]. 1976 Jul-Aug Fiziol Zh pmid:1001539
Maitre M et al. In vitro studies into the effect of inhibition of rat brain succinic semialdehyde dehydrogenase on GABA synthesis and degradation. 1976 FEBS Lett. pmid:1001470
Curtis DR et al. Central actions of benzodiazepines. 1976 Brain Res. pmid:1000299
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