4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Stefanova N et al. | Sex and age differences of neurons expressing GABA-immunoreactivity in the rat bed nucleus of the stria terminalis. | 1998 | Int. J. Dev. Neurosci. | pmid:9881292 |
Szabat E et al. | The ontogenic appearance of tyrosine hydroxylase-, serotonin-, gamma-aminobutyric acid-, calcitonin gene-related peptide-, substance P-, and synaptophysin-immunoreactivity in rat pituitary gland. | 1998 | Int. J. Dev. Neurosci. | pmid:9881293 |
Gravielle MC et al. | GABA-stimulated chloride uptake during avian CNS development: modulation by neurosteroids. | 1998 | Int. J. Dev. Neurosci. | pmid:9881295 |
Hilbig H et al. | Cytoarchitecture of the tectum opticum in the Japanese quail. | 1998 | Neuroscience | pmid:9881878 |
Jouvenceau A et al. | Alteration of NMDA receptor-mediated synaptic responses in CA1 area of the aged rat hippocampus: contribution of GABAergic and cholinergic deficits. | 1998 | Hippocampus | pmid:9882020 |
Aistrup GL et al. | Ethanol modulation of nicotinic acetylcholine receptor currents in cultured cortical neurons. | 1999 | Mol. Pharmacol. | pmid:9882696 |
Neelands TR et al. | Spontaneous and gamma-aminobutyric acid (GABA)-activated GABA(A) receptor channels formed by epsilon subunit-containing isoforms. | 1999 | Mol. Pharmacol. | pmid:9882711 |
Bulfone A et al. | An olfactory sensory map develops in the absence of normal projection neurons or GABAergic interneurons. | 1998 | Neuron | pmid:9883721 |
Wilner AN | New medication options for patients with epilepsy. | 1998 | Med Health R I | pmid:9884541 |
Abi-Saab WM et al. | 5-HT2 receptor regulation of extracellular GABA levels in the prefrontal cortex. | 1999 | Neuropsychopharmacology | pmid:9885788 |