4-aminobutyric acid

4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.

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Introduction

To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-aminobutyric acid?

4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid

MeSH term MeSH ID Detail
Confusion D003221 4 associated lipids
Constriction, Pathologic D003251 8 associated lipids
Coronary Disease D003327 70 associated lipids
Cough D003371 19 associated lipids
Cranial Nerve Diseases D003389 1 associated lipids
Cushing Syndrome D003480 5 associated lipids
Dandy-Walker Syndrome D003616 1 associated lipids
Death, Sudden D003645 12 associated lipids
Decerebrate State D003655 7 associated lipids
Drug Eruptions D003875 30 associated lipids
Diabetes Insipidus D003919 5 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Diplopia D004172 2 associated lipids
Down Syndrome D004314 18 associated lipids
Duodenal Ulcer D004381 12 associated lipids
Dysarthria D004401 2 associated lipids
Dyskinesia, Drug-Induced D004409 15 associated lipids
Dystonia D004421 3 associated lipids
Dystonia Musculorum Deformans D004422 1 associated lipids
Earache D004433 2 associated lipids
Encephalitis D004660 15 associated lipids
Encephalomyelitis, Venezuelan Equine D004685 1 associated lipids
Epilepsy D004827 35 associated lipids
Epilepsies, Partial D004828 3 associated lipids
Epilepsy, Tonic-Clonic D004830 2 associated lipids
Epilepsy, Absence D004832 5 associated lipids
Epilepsy, Temporal Lobe D004833 4 associated lipids
Epilepsy, Post-Traumatic D004834 1 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Esophageal and Gastric Varices D004932 2 associated lipids
Esotropia D004948 1 associated lipids
Exanthema D005076 11 associated lipids
Fetal Hypoxia D005311 3 associated lipids
Fetal Diseases D005315 8 associated lipids
Fetal Growth Retardation D005317 9 associated lipids
Fetal Resorption D005327 15 associated lipids
Fever D005334 35 associated lipids
Filariasis D005368 6 associated lipids
Gigantism D005877 1 associated lipids
Tourette Syndrome D005879 3 associated lipids
Glioma D005910 112 associated lipids
Pantothenate Kinase-Associated Neurodegeneration D006211 1 associated lipids
Hamartoma D006222 2 associated lipids
Heart Arrest D006323 13 associated lipids
Hemolysis D006461 131 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Hepatic Encephalopathy D006501 9 associated lipids
Hepatitis A D006506 8 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 4-aminobutyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 4-aminobutyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 4-aminobutyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-aminobutyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-aminobutyric acid

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Authors Title Published Journal PubMed Link
Trotti LM et al. Clarithromycin in γ-aminobutyric acid-Related hypersomnolence: A randomized, crossover trial. 2015 Ann. Neurol. pmid:26094838
Zhao W et al. A study on quality components and sleep-promoting effects of GABA black tea. 2015 Food Funct pmid:26290415
Bönnighausen J et al. Disruption of the GABA shunt affects mitochondrial respiration and virulence in the cereal pathogen Fusarium graminearum. 2015 Mol. Microbiol. pmid:26305050
Mirabella R et al. WRKY40 and WRKY6 act downstream of the green leaf volatile E-2-hexenal in Arabidopsis. 2015 Plant J. pmid:26243404
Sikoglu EM et al. Vitamin D3 Supplemental Treatment for Mania in Youth with Bipolar Spectrum Disorders. 2015 J Child Adolesc Psychopharmacol pmid:26091195
Villumsen IS et al. Pharmacological characterisation of murine α4β1δ GABAA receptors expressed in Xenopus oocytes. 2015 BMC Neurosci pmid:25887256
Ordoñez L et al. Spontaneous reporting of Stevens-Johnson syndrome and toxic epidermal necrolysis associated with antiepileptic drugs. 2015 Eur Rev Med Pharmacol Sci pmid:26221907
Hieda K et al. Pharmacological effect of functional foods with a hypotensive action. 2015 Nippon Yakurigaku Zasshi pmid:26165340
Lee SH et al. Multiple Forms of Endocannabinoid and Endovanilloid Signaling Regulate the Tonic Control of GABA Release. 2015 J. Neurosci. pmid:26157003
Inkpen H Chronic progressive polyarthritis in a domestic shorthair cat. 2015 Can. Vet. J. pmid:26028686