4-aminobutyric acid

4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.

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Introduction

To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-aminobutyric acid?

4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid

MeSH term MeSH ID Detail
Retinal Artery Occlusion D015356 2 associated lipids
Reperfusion Injury D015427 65 associated lipids
Weight Gain D015430 101 associated lipids
Weight Loss D015431 56 associated lipids
Granuloma, Foreign-Body D015745 5 associated lipids
Gyrate Atrophy D015799 2 associated lipids
Ocular Motility Disorders D015835 2 associated lipids
Arachnoid Cysts D016080 1 associated lipids
Postpoliomyelitis Syndrome D016262 1 associated lipids
Gangliosidosis, GM1 D016537 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 4-aminobutyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 4-aminobutyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 4-aminobutyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-aminobutyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-aminobutyric acid

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Authors Title Published Journal PubMed Link
El Hage M et al. Effects of valproate on glutamate metabolism in rat brain slices: a (13)C NMR study. 2012 Epilepsy Res. pmid:22088480
Miklós IH and Kovács KJ Reorganization of synaptic inputs to the hypothalamic paraventricular nucleus during chronic psychogenic stress in rats. 2012 Biol. Psychiatry pmid:22137593
Hazell GG et al. G protein-coupled receptors in the hypothalamic paraventricular and supraoptic nuclei--serpentine gateways to neuroendocrine homeostasis. 2012 Front Neuroendocrinol pmid:21802439
Hagerman R et al. Fragile X syndrome and targeted treatment trials. 2012 Results Probl Cell Differ pmid:22009360
Li WR et al. Pharmacokinetics of natural borneol after oral administration in mice brain and its effect on excitation ratio. 2012 Eur J Drug Metab Pharmacokinet pmid:21948240
Wang M et al. Acute restraint stress enhances hippocampal endocannabinoid function via glucocorticoid receptor activation. 2012 J. Psychopharmacol. (Oxford) pmid:21890595
Ihara D et al. Deltamethrin, a type II pyrethroid insecticide, has neurotrophic effects on neurons with continuous activation of the Bdnf promoter. 2012 Neuropharmacology pmid:22079160
Nugent BM et al. Kinases SPAK and OSR1 are upregulated by estradiol and activate NKCC1 in the developing hypothalamus. 2012 J. Neurosci. pmid:22238094
Bosch OG et al. Reconsidering GHB: orphan drug or new model antidepressant? 2012 J. Psychopharmacol. (Oxford) pmid:21926421
Dahl SR et al. Determination of γ-hydroxybutyrate (GHB), β-hydroxybutyrate (BHB), pregabalin, 1,4-butane-diol (1,4BD) and γ-butyrolactone (GBL) in whole blood and urine samples by UPLC-MSMS. 2012 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:22226469
Lucenteforte E et al. Complementary and Alternative Drugs Use among Preoperative Patients: A Cross-Sectional Study in Italy. 2012 Evid Based Complement Alternat Med pmid:21822441
Schuller HM et al. Regulation of pancreatic cancer by neuropsychological stress responses: a novel target for intervention. 2012 Carcinogenesis pmid:22072614
Beate K et al. Genetics of isolated hypogonadotropic hypogonadism: role of GnRH receptor and other genes. 2012 Int J Endocrinol pmid:22229029
Al-Wadei HA et al. Social stress promotes and γ-aminobutyric acid inhibits tumor growth in mouse models of non-small cell lung cancer. 2012 Cancer Prev Res (Phila) pmid:21955519
Nothdurfter C et al. Recent developments in potential anxiolytic agents targeting GABAA/BzR complex or the translocator protein (18kDa) (TSPO). 2012 Curr Top Med Chem pmid:22204486
López-López J et al. Inferior alveolar nerve injury resulting from overextension of an endodontic sealer: non-surgical management using the GABA analogue pregabalin. 2012 Int Endod J pmid:21883296
Yalçın O Genes and molecular mechanisms involved in the epileptogenesis of idiopathic absence epilepsies. 2012 Seizure pmid:22206818
Duszczyk-Budhathoki M et al. Administration of thimerosal to infant rats increases overflow of glutamate and aspartate in the prefrontal cortex: protective role of dehydroepiandrosterone sulfate. 2012 Neurochem. Res. pmid:22015977
Wu TY et al. Effect of antioxidant activity and functional properties of Chingshey purple sweet potato fermented milk by Lactobacillus acidophilus, L. delbrueckii subsp. lactis, and L. gasseri strains. 2012 J. Food Sci. pmid:22182227
Merewitz EB et al. Elevated cytokinin content in ipt transgenic creeping bentgrass promotes drought tolerance through regulating metabolite accumulation. 2012 J. Exp. Bot. pmid:22131157