4-aminobutyric acid

4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.

Cross Reference

Introduction

To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-aminobutyric acid?

4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid

MeSH term MeSH ID Detail
Postpoliomyelitis Syndrome D016262 1 associated lipids
Stiff-Person Syndrome D016750 1 associated lipids
Gangliosidoses, GM2 D020143 1 associated lipids
Tetanus D013742 1 associated lipids
Pantothenate Kinase-Associated Neurodegeneration D006211 1 associated lipids
Nervous System Malformations D009421 1 associated lipids
Epilepsy, Complex Partial D017029 1 associated lipids
Myofascial Pain Syndromes D009209 1 associated lipids
Encephalomyelitis, Venezuelan Equine D004685 1 associated lipids
Meningitis, Aseptic D008582 1 associated lipids
Per page 10 20 50 100 | Total 280

PubChem Associated disorders and diseases

What pathways are associated with 4-aminobutyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with 4-aminobutyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with 4-aminobutyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-aminobutyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-aminobutyric acid

Download all related citations
Per page 10 20 50 100 | Total 40318
Authors Title Published Journal PubMed Link
Ilinsky IA et al. Mode of termination of pallidal afferents to the thalamus: a light and electron microscopic study with anterograde tracers and immunocytochemistry in Macaca mulatta. 1997 J. Comp. Neurol. pmid:9378854
Kultas-Ilinsky K et al. Pallidal afferent territory of the Macaca mulatta thalamus: neuronal and synaptic organization of the VAdc. 1997 J. Comp. Neurol. pmid:9378853
Rufo M et al. [Monotherapy with vigabatrin in the treatment of West's syndrome]. 1997 Rev Neurol pmid:9377291
Caraballo R et al. [West's syndrome in patients with cerebral paralysis and periventricular leukomalacia: a good response to treatment]. 1997 Rev Neurol pmid:9377290
Veinante P et al. GABA- and peptide-immunoreactivities co-localize in the rat central extended amygdala. 1997 Neuroreport pmid:9376543
Ferraro L et al. The antinarcoleptic drug modafinil increases glutamate release in thalamic areas and hippocampus. 1997 Neuroreport pmid:9376524
Ramanathan VK et al. Na+-dependent gamma-aminobutyric acid (GABA) transport in the choroid plexus of rabbit. 1997 Biochim. Biophys. Acta pmid:9375816
Ghose S et al. N-acetylaspartylglutamate stimulates metabotropic glutamate receptor 3 to regulate expression of the GABA(A) alpha6 subunit in cerebellar granule cells. 1997 J. Neurochem. pmid:9375663
Ito S and Sved AF Influence of GABA in the nucleus of the solitary tract on blood pressure in baroreceptor-denervated rats. 1997 Am. J. Physiol. pmid:9374806
Seidel C and Bicker G Colocalization of NADPH-diaphorase and GABA-immunoreactivity in the olfactory and visual system of the locust. 1997 Brain Res. pmid:9374195
Volpi R et al. Different control mechanisms of growth hormone (GH) secretion between gamma-amino- and gamma-hydroxy-butyric acid: neuroendocrine evidence in Parkinson's disease. 1997 Psychoneuroendocrinology pmid:9373886
De Felipe J et al. Inhibitory synaptogenesis in mouse somatosensory cortex. 1997 Oct-Nov Cereb. Cortex pmid:9373018
Kushner SA et al. Gamma-vinyl GABA attenuates cocaine-induced lowering of brain stimulation reward thresholds. 1997 Psychopharmacology (Berl.) pmid:9372539
Houtchens MK et al. Open label gabapentin treatment for pain in multiple sclerosis. 1997 Mult. Scler. pmid:9372509
Karlsson U et al. Currents evoked by GABA and glycine in acutely dissociated neurons from the rat medial preoptic nucleus. 1997 Brain Res. pmid:9372227
Reith CA and Sillar KT Pre- and postsynaptic modulation of spinal GABAergic neurotransmission by the neurosteroid, 5 beta-pregnan-3 alpha-ol-20-one. 1997 Brain Res. pmid:9372220
Tashiro Y et al. Functional injury of cholinergic, GABAergic and dopaminergic systems in the basal ganglia of adult rat with kaolin-induced hydrocephalus. 1997 Brain Res. pmid:9372201
Bhandal NS et al. Channel gating in the absence of agonist by a homo-oligomeric molluscan GABA receptor expressed in Xenopus oocytes from a cloned cDNA. 1995 Invert. Neurosci. pmid:9372148
Maule AG et al. Inhibitory effects of nematode FMRFamide-related peptides (FaRPs) on muscle strips from Ascaris suum. 1995 Invert. Neurosci. pmid:9372147
Khatri A and Pearlstein L Pain in Guillain-Barré syndrome. 1997 Neurology pmid:9371954
Panayiotopoulos CP et al. Vigabatrin aggravates absences and absence status. 1997 Neurology pmid:9371946
Chudnow RS et al. Gabapentin for familial paroxysmal dystonic choreoathetosis. 1997 Neurology pmid:9371936
Lavoie AM et al. Activation and deactivation rates of recombinant GABA(A) receptor channels are dependent on alpha-subunit isoform. 1997 Biophys. J. pmid:9370445
McCarthy MM et al. Excitatory neurotransmission and sexual differentiation of the brain. 1997 Brain Res. Bull. pmid:9370215
Herbison AE Estrogen regulation of GABA transmission in rat preoptic area. 1997 Brain Res. Bull. pmid:9370195
Mitsuma T et al. Effects of gamma-butyric acid on the release of thyrotropin-releasing hormone from the rat retina in vitro. 1997 Horm. Metab. Res. pmid:9370109
Pow DV and Crook DK Immunocytochemical analysis of the transport of arginine analogues into nitrergic neurons and other cells in the retina and pituitary. 1997 Cell Tissue Res. pmid:9369527
Ferreira IL et al. 'Chemical ischemia' in cultured retina cells: the role of excitatory amino acid receptors and of energy levels on cell death. 1997 Brain Res. pmid:9369312
Plotkin MD et al. Expression of the Na-K-2Cl cotransporter is developmentally regulated in postnatal rat brains: a possible mechanism underlying GABA's excitatory role in immature brain. 1997 J. Neurobiol. pmid:9369151
Brownlee DJ et al. Actions of the anthelmintic ivermectin on the pharyngeal muscle of the parasitic nematode, Ascaris suum. 1997 Parasitology pmid:9368907
Takada K and Yanagita T Drug dependence study on vigabatrin in rhesus monkeys and rats. 1997 Arzneimittelforschung pmid:9368699
Le Foll F et al. Multiple modulatory effects of the neuroactive steroid pregnanolone on GABAA receptor in frog pituitary melanotrophs. 1997 J. Physiol. (Lond.) pmid:9365913
Sastry BR et al. GABA-ergic transmission in deep cerebellar nuclei. 1997 Prog. Neurobiol. pmid:9364613
Rowley HL et al. Generalised seizure-induced changes in rat hippocampal glutamate but not GABA release are potentiated by repeated seizures. 1997 Neurosci. Lett. pmid:9364518
Monaco F et al. Lack of association between vigabatrin and impaired cognition. 1997 Sep-Oct J. Int. Med. Res. pmid:9364292
Herron P et al. Distribution of neurons immunoreactive for parvalbumin and calbindin in the somatosensory thalamus of the raccoon. 1997 J. Comp. Neurol. pmid:9364242
Fletcher EL and Kalloniatis M Neurochemical development of the degenerating rat retina. 1997 J. Comp. Neurol. pmid:9364235
Soltis RP et al. Interaction of GABA and excitatory amino acids in the basolateral amygdala: role in cardiovascular regulation. 1997 J. Neurosci. pmid:9364082
Dittman JS and Regehr WG Mechanism and kinetics of heterosynaptic depression at a cerebellar synapse. 1997 J. Neurosci. pmid:9364051
Hémar A et al. Dendroaxonal transcytosis of transferrin in cultured hippocampal and sympathetic neurons. 1997 J. Neurosci. pmid:9364049
Schnee M et al. Pharmacology of skeletal muscle GABA-gated chloride channels in the cockroach Periplaneta americana. 1997 J. Exp. Biol. pmid:9359880
Verveer C et al. Ultrastructural study of the GABAergic and cerebellar input to the nucleus reticularis tegmenti pontis. 1997 Brain Res. pmid:9359619
Sinnamon HM and Benaur M GABA injected into the anterior dorsal tegmentum (ADT) of the midbrain blocks stepping initiated by stimulation of the hypothalamus. 1997 Brain Res. pmid:9359615
Pombal MA et al. Organization of the lamprey striatum - transmitters and projections. 1997 Brain Res. pmid:9359610
Kobayashi M et al. Immunohistochemical studies on glutamatergic, GABAergic and glycinergic axon varicosities presynaptic to parasympathetic preganglionic neurons in the superior salivatory nucleus of the rat. 1997 Brain Res. pmid:9359589
Alexander GM et al. Intracerebral microdialysis study of glutamate reuptake in awake, behaving rats. 1997 Brain Res. pmid:9359581
Pohujani SM et al. Effect of adenergic blocking agents on the brain gamma-aminobutyric acid content of mice. 1976 Indian J. Med. Res. pmid:9358
Armijo JA et al. Vigabatrin serum concentration to dosage ratio: influence of age and associated antiepileptic drugs. 1997 Ther Drug Monit pmid:9357089
Cupello A et al. Effect of nitric oxide donors on GABA uptake by rat brain synaptosomes. 1997 Neurochem. Res. pmid:9357019
Jaffe EH and Garcia Y Excitatory sulfur-containing amino acid-induced release of [3H]GABA from rat olfactory bulb. 1997 Neurochem. Res. pmid:9357013
Yang L and Benardo LS Epileptogenesis following neocortical trauma from two sources of disinhibition. 1997 J. Neurophysiol. pmid:9356429
Lamsa K and Kaila K Ionic mechanisms of spontaneous GABAergic events in rat hippocampal slices exposed to 4-aminopyridine. 1997 J. Neurophysiol. pmid:9356408
Qian H et al. GABA receptors of bipolar cells from the skate retina: actions of zinc on GABA-mediated membrane currents. 1997 J. Neurophysiol. pmid:9356392
Zhang SJ et al. GABAA receptor-mediated Cl- currents in rat thalamic reticular and relay neurons. 1997 J. Neurophysiol. pmid:9356381
Cañadas S et al. Protection by GABA and succinic semialdehyde of seed germination and some enzymatic activities against high concentration of hydroxylamine. 1976 Rev. Esp. Fisiol. pmid:935625
Sagrillo CA and Selmanoff M Castration decreases single cell levels of mRNA encoding glutamic acid decarboxylase in the diagonal band of broca and the sexually dimorphic nucleus of the preoptic area. 1997 J. Neuroendocrinol. pmid:9355037
Lainé-Cessac P et al. Mechanisms of the inhibition of human erythrocyte pyridoxal kinase by drugs. 1997 Biochem. Pharmacol. pmid:9354586
Rodríguez-Moreno A et al. Kainate receptors presynaptically downregulate GABAergic inhibition in the rat hippocampus. 1997 Neuron pmid:9354335
Skolnick P et al. [3H]RY 80: A high-affinity, selective ligand for gamma-aminobutyric acidA receptors containing alpha-5 subunits. 1997 J. Pharmacol. Exp. Ther. pmid:9353361
Drew KL et al. Non-exocytotic GABA overflow in rat striatum inhibits gnawing. 1997 Life Sci. pmid:9353168
pmid:9352959
Hotujac L et al. Verruculogen: a new substance for decreasing of GABA levels in CNS. 1976 Pharmacology pmid:935244
Hydén H et al. Modulation by calcium of Deiters' neuron GABAA receptors in the rabbit. 1997 Int. J. Neurosci. pmid:9352425
Kalyuzhny AE and Wessendorf MW CNS GABA neurons express the mu-opioid receptor: immunocytochemical studies. 1997 Neuroreport pmid:9351674
Green MA and Halliwell RF Selective antagonism of the GABA(A) receptor by ciprofloxacin and biphenylacetic acid. 1997 Br. J. Pharmacol. pmid:9351519
Qume M and Fowler LJ Effect of chronic treatment with the GABA transaminase inhibitors gamma-vinyl GABA and ethanolamine O-sulphate on the in vitro GABA release from rat hippocampus. 1997 Br. J. Pharmacol. pmid:9351512
pmid:9350844
McIntire SL et al. Identification and characterization of the vesicular GABA transporter. 1997 Nature pmid:9349821
Sanchez-Vives MV et al. Inhibitory interactions between perigeniculate GABAergic neurons. 1997 J. Neurosci. pmid:9348356
Sanchez-Vives MV and McCormick DA Functional properties of perigeniculate inhibition of dorsal lateral geniculate nucleus thalamocortical neurons in vitro. 1997 J. Neurosci. pmid:9348355
Tsumori T and Yasui Y Organization of the nigro-tecto-bulbar pathway to the parvicellular reticular formation: a light- and electron-microscopic study in the rat. 1997 Exp Brain Res pmid:9348132
Gruenthal M et al. Gabapentin for the treatment of spasticity in patients with spinal cord injury. 1997 Spinal Cord pmid:9347598
Wenzel HJ et al. Ultrastructural localization of neurotransmitter immunoreactivity in mossy cell axons and their synaptic targets in the rat dentate gyrus. 1997 Hippocampus pmid:9347352
Scotti AL et al. Loss of perikaryal parvalbumin immunoreactivity from surviving GABAergic neurons in the CA1 field of epileptic gerbils. 1997 Hippocampus pmid:9347349
Young LT et al. Acute treatment of bipolar depression with gabapentin. 1997 Biol. Psychiatry pmid:9347136
McEntee WJ Wernicke's encephalopathy: an excitotoxicity hypothesis. 1997 Metab Brain Dis pmid:9346467
Mecarelli O et al. Vigabatrin versus carbamazepine and phenytoin in kainic acid-treated pubescent rats. 1997 Pharmacol. Res. pmid:9344635
Shuaib A et al. GABA and glutamate levels in the substantia nigra reticulata following repetitive cerebral ischemia in gerbils. 1997 Exp. Neurol. pmid:9344556
Mishra RK and Hollett CR The effect of a bovine hypothalamic factor on mouse brain neurotransmitters. 1976 Neuropharmacology pmid:934447
Omer VV Rat brain GABA and glutamate content in m-fluorotyrosine convulsions. 1976 Neuropharmacology pmid:934443
Bowery NG et al. Bicyclic phosphorus esters that are potent convulsants and GABA antagonists. 1976 Nature pmid:934303
Lu Y et al. GABAergic disinhibition changes the recovery cycle of bat inferior collicular neurons. 1997 J. Comp. Physiol. A pmid:9342856
de la Iglesia FA et al. alpha2u-Globulin nephropathy and ravens: do ravens of a different feather flock together? 1997 Environ. Health Perspect. pmid:9341098
Sist TC et al. Experience with gabapentin for neuropathic pain in the head and neck: report of ten cases. 1997 Sep-Oct Reg Anesth pmid:9338912
Picard C et al. Alopecia associated with gabapentin: first case. 1997 Ann Pharmacother pmid:9337455
Hashimoto I et al. High-frequency magnetic signals in the human somatosensory cortex. 1996 Electroencephalogr Clin Neurophysiol Suppl pmid:9335970
Mayer M Kainate receptors. Finding homes at synapses. 1997 Nature pmid:9335486
Fontana G et al. Gp120 can revert antagonism at the glycine site of NMDA receptors mediating GABA release from cultured hippocampal neurons. 1997 J. Neurosci. Res. pmid:9335260
Abercrombie ED and DeBoer P Substantia nigra D1 receptors and stimulation of striatal cholinergic interneurons by dopamine: a proposed circuit mechanism. 1997 J. Neurosci. pmid:9334422
Hájos N and Mody I Synaptic communication among hippocampal interneurons: properties of spontaneous IPSCs in morphologically identified cells. 1997 J. Neurosci. pmid:9334415
Roerig B and Katz LC Modulation of intrinsic circuits by serotonin 5-HT3 receptors in developing ferret visual cortex. 1997 J. Neurosci. pmid:9334407
Tamamaki N et al. Origin and route of tangentially migrating neurons in the developing neocortical intermediate zone. 1997 J. Neurosci. pmid:9334406
Toth Z et al. Instantaneous perturbation of dentate interneuronal networks by a pressure wave-transient delivered to the neocortex. 1997 J. Neurosci. pmid:9334386
Anderson SA et al. Interneuron migration from basal forebrain to neocortex: dependence on Dlx genes. 1997 Science pmid:9334308
Rabbaa L et al. Absorption of ofloxacin isomers in the rat small intestine. 1997 Antimicrob. Agents Chemother. pmid:9333061
White HS et al. Topiramate enhances GABA-mediated chloride flux and GABA-evoked chloride currents in murine brain neurons and increases seizure threshold. 1997 Epilepsy Res. pmid:9332882
Falkenberg T et al. GABA release and GAD67 mRNA expression in rat hippocampus following entorhinal cortex activation. 1997 Brain Res. Mol. Brain Res. pmid:9332739
Minson JB et al. c-fos identifies GABA-synthesizing barosensitive neurons in caudal ventrolateral medulla. 1997 Neuroreport pmid:9331908
Wallace KL Antibiotic-induced convulsions. 1997 Crit Care Clin pmid:9330839
Jiang M and Swann JW Expression of calretinin in diverse neuronal populations during development of rat hippocampus. 1997 Neuroscience pmid:9330374