4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Schumacher M et al. | Progesterone synthesis in the nervous system: implications for myelination and myelin repair. | 2012 | Front Neurosci | pmid:22347156 |
Mathew J et al. | Decreased GABA receptor in the cerebral cortex of epileptic rats: effect of Bacopa monnieri and Bacoside-A. | 2012 | J. Biomed. Sci. | pmid:22364254 |
Malek AA et al. | Absence of membrane phosphatidylcholine does not affect virulence and stress tolerance phenotypes in the opportunistic pathogen Pseudomonas aeruginosa. | 2012 | PLoS ONE | pmid:22363496 |
Chamma I et al. | Role of the neuronal K-Cl co-transporter KCC2 in inhibitory and excitatory neurotransmission. | 2012 | Front Cell Neurosci | pmid:22363264 |
Yoshimura Y et al. | Different localization patterns of anthocyanin species in the pericarp of black rice revealed by imaging mass spectrometry. | 2012 | PLoS ONE | pmid:22363605 |
Szczot M et al. | Modulation of GABAergic synaptic currents and current responses by α-thujone and dihydroumbellulone. | 2012 | J. Nat. Prod. | pmid:22364543 |
Balagurunathan B et al. | Reconstruction and analysis of a genome-scale metabolic model for Scheffersomyces stipitis. | 2012 | Microb. Cell Fact. | pmid:22356827 |