4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Gernert M et al. | Alterations in spontaneous single unit activity of striatal subdivisions during ontogenesis in mutant dystonic hamsters. | 1999 | Brain Res. | pmid:10064814 |
Ye JH et al. | Cocaine and lidocaine have additive inhibitory effects on the GABAA current of acutely dissociated hippocampal pyramidal neurons. | 1999 | Brain Res. | pmid:10064784 |
Ribak CE et al. | Immunocytochemical localization of glutamate decarboxylase in the substantia nigra of the rat. | 1976 | Res Publ Assoc Res Nerv Ment Dis | pmid:1005902 |
Roberts E | Some thoughts about GABA and the basal ganglia. | 1976 | Res Publ Assoc Res Nerv Ment Dis | pmid:1005901 |
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Redburn DA | Relationship between synaptosomal uptake and release of [14C]gaba, [14C]diaminobutyric acid and [14C]beta-alanine. | 1978 | J. Neurochem. | pmid:100577 |
Hikino H et al. | Hypotensive principle of Astragalus and Hedysarum roots. | 1976 | Planta Med. | pmid:1005534 |
Lei H and Peeling J | Simultaneous lactate editing and observation of other metabolites using a stimulated-echo-enhanced double-quantum filter. | 1999 | J. Magn. Reson. | pmid:10053150 |