4-aminobutyric acid

4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.

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Introduction

To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-aminobutyric acid?

4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid

MeSH term MeSH ID Detail
Epilepsy, Post-Traumatic D004834 1 associated lipids
Epilepsy, Temporal Lobe D004833 4 associated lipids
Epilepsy, Absence D004832 5 associated lipids
Epilepsy, Tonic-Clonic D004830 2 associated lipids
Epilepsies, Partial D004828 3 associated lipids
Epilepsy D004827 35 associated lipids
Encephalomyelitis, Venezuelan Equine D004685 1 associated lipids
Encephalitis D004660 15 associated lipids
Earache D004433 2 associated lipids
Dystonia Musculorum Deformans D004422 1 associated lipids
Dystonia D004421 3 associated lipids
Dyskinesia, Drug-Induced D004409 15 associated lipids
Dysarthria D004401 2 associated lipids
Duodenal Ulcer D004381 12 associated lipids
Down Syndrome D004314 18 associated lipids
Diplopia D004172 2 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Diabetes Insipidus D003919 5 associated lipids
Drug Eruptions D003875 30 associated lipids
Decerebrate State D003655 7 associated lipids
Death, Sudden D003645 12 associated lipids
Dandy-Walker Syndrome D003616 1 associated lipids
Cushing Syndrome D003480 5 associated lipids
Cranial Nerve Diseases D003389 1 associated lipids
Cough D003371 19 associated lipids
Coronary Disease D003327 70 associated lipids
Constriction, Pathologic D003251 8 associated lipids
Confusion D003221 4 associated lipids
Common Bile Duct Diseases D003137 3 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Cleft Palate D002972 9 associated lipids
Choristoma D002828 1 associated lipids
Chorea D002819 1 associated lipids
Cestode Infections D002590 3 associated lipids
Cerebrovascular Disorders D002561 25 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Brain Ischemia D002545 89 associated lipids
Cerebral Hemorrhage D002543 13 associated lipids
Hypoxia, Brain D002534 5 associated lipids
Cerebellar Neoplasms D002528 9 associated lipids
Cerebellar Ataxia D002524 3 associated lipids
Central Nervous System Diseases D002493 10 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Causalgia D002422 1 associated lipids
Catatonia D002389 2 associated lipids
Catalepsy D002375 30 associated lipids
Brain Edema D001929 20 associated lipids
Brain Diseases, Metabolic D001928 9 associated lipids
Brain Diseases D001927 27 associated lipids
Brain Damage, Chronic D001925 6 associated lipids
Bradycardia D001919 13 associated lipids
Body Weight D001835 333 associated lipids
Urinary Bladder, Neurogenic D001750 3 associated lipids
Basal Ganglia Diseases D001480 8 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Athetosis D001264 1 associated lipids
Ataxia D001259 20 associated lipids
Asthenia D001247 5 associated lipids
Asphyxia D001237 5 associated lipids
Ascorbic Acid Deficiency D001206 9 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Arthritis D001168 41 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Arachnoiditis D001100 1 associated lipids
Aphakia D001035 1 associated lipids
Amyotrophic Lateral Sclerosis D000690 11 associated lipids
Amnesia, Retrograde D000648 2 associated lipids
Amnesia D000647 12 associated lipids
Renal Aminoacidurias D000608 2 associated lipids
Alzheimer Disease D000544 76 associated lipids
Alcoholism D000437 27 associated lipids
Alcoholic Intoxication D000435 15 associated lipids
Alcohol Amnestic Disorder D000425 2 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Adrenal Cortex Diseases D000303 1 associated lipids
Adenoma D000236 40 associated lipids
Adenocarcinoma D000230 166 associated lipids
Acidosis, Lactic D000140 8 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 4-aminobutyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 4-aminobutyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 4-aminobutyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-aminobutyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-aminobutyric acid

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Per page 10 20 50 100 | Total 40318
Authors Title Published Journal PubMed Link
Perrais D and Ropert N Effect of zolpidem on miniature IPSCs and occupancy of postsynaptic GABAA receptors in central synapses. 1999 J. Neurosci. pmid:9880578
Jin Y et al. The Caenorhabditis elegans gene unc-25 encodes glutamic acid decarboxylase and is required for synaptic transmission but not synaptic development. 1999 J. Neurosci. pmid:9880574
Glitsch M and Marty A Presynaptic effects of NMDA in cerebellar Purkinje cells and interneurons. 1999 J. Neurosci. pmid:9880571
Feely M Fortnightly review: drug treatment of epilepsy. 1999 BMJ pmid:9880286
Yan XX and Ribak CE Alteration of GABA transporter expression in the rat cerebral cortex following needle puncture and colchicine injection. 1999 Brain Res. pmid:9878808
Ikarashi Y et al. Modulation of acetylcholine release via GABAA and GABAB receptors in rat striatum. 1999 Brain Res. pmid:9878759
Commons KG et al. In the ventromedial nucleus of the rat hypothalamus, GABA-immunolabeled neurons are abundant and are innervated by both enkephalin- and GABA-immunolabeled axon terminals. 1999 Brain Res. pmid:9878688
Serrao M et al. A case of myokymia-cramp syndrome successfully treated with gabapentin. 1998 Acta Neurol. Scand. pmid:9875627
Brockhaus J and Ballanyi K Synaptic inhibition in the isolated respiratory network of neonatal rats. 1998 Eur. J. Neurosci. pmid:9875360
Cattaert D and Le Ray D Direct glutamate-mediated presynaptic inhibition of sensory afferents by the postsynaptic motor neurons. 1998 Eur. J. Neurosci. pmid:9875352
Gonzalez LE et al. Stimulation of benzodiazepine receptors in the dorsal hippocampus and median raphé reveals differential GABAergic control in two animal tests of anxiety. 1998 Eur. J. Neurosci. pmid:9875346
Pernberg J et al. Structure and dynamics of receptive fields in the visual cortex of the cat (area 18) and the influence of GABAergic inhibition. 1998 Eur. J. Neurosci. pmid:9875339
Wickelgren I Drug may suppress the craving for nicotine. 1998 Science pmid:9874627
Czupryn A et al. Neurotransmitter system markers in adult barrel field. 1998 Somatosens Mot Res pmid:9874522
Kogo M et al. Examination of the relationships between jaw opener and closer rhythmical muscle activity in an in vitro brainstem jaw-attached preparation. 1998 Somatosens Mot Res pmid:9874519
Bonanno G et al. GABA(B) receptors as potential targets for drugs able to prevent excessive excitatory amino acid transmission in the spinal cord. 1998 Eur. J. Pharmacol. pmid:9874164
McGraw T and Stacey BR Gabapentin for treatment of neuropathic pain in a 12-year-old girl. 1998 Clin J Pain pmid:9874016
Carruthers NI et al. Synthesis of a series of sulfinic acid analogs of GABA and evaluation of their GABAB receptor affinities. 1998 Bioorg. Med. Chem. Lett. pmid:9873676
Serfass L and Casara PJ General synthesis of 3-substituted alkenyl GABA as potential anticonvulsants. 1998 Bioorg. Med. Chem. Lett. pmid:9873588
Bernstein EM and Quick MW Regulation of gamma-aminobutyric acid (GABA) transporters by extracellular GABA. 1999 J. Biol. Chem. pmid:9873028