4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Summa M et al. | Presynaptic mGlu7 receptors control GABA release in mouse hippocampus. | 2013 | Neuropharmacology | pmid:22564442 |
Omole F et al. | Easing the burden of premenstrual dysphoric disorder. | 2013 | J Fam Pract | pmid:23326823 |
de Souza LM and Franci CR | Differential immunoreactivity of glucocorticoid receptor and GABA in GABAergic afferents to parvocellular neurons in the paraventricular nucleus. | 2013 | Neurosci. Lett. | pmid:23276637 |
Anneken JH et al. | MDMA increases glutamate release and reduces parvalbumin-positive GABAergic cells in the dorsal hippocampus of the rat: role of cyclooxygenase. | 2013 | J Neuroimmune Pharmacol | pmid:23179355 |
Egashira N et al. | Effects of mood stabilizers on marble-burying behavior in mice: involvement of GABAergic system. | 2013 | Psychopharmacology (Berl.) | pmid:23086022 |
Esser D et al. | Unraveling the function of paralogs of the aldehyde dehydrogenase super family from Sulfolobus solfataricus. | 2013 | Extremophiles | pmid:23296511 |
Beigi M et al. | TCA cycle involved enzymes SucA and Kgd, as well as MenD: efficient biocatalysts for asymmetric C-C bond formation. | 2013 | Org. Lett. | pmid:23317369 |
Han B et al. | Quantitative LC-MS/MS analysis of arachidonoyl amino acids in mouse brain with treatment of FAAH inhibitor. | 2013 | Anal. Biochem. | pmid:23044255 |
Nizeica V et al. | Bortezomib induced a phrenic palsy in a multiple myeloma patient. | 2013 | Ann. Hematol. | pmid:23370597 |
Hasan A et al. | Epigenetic dysregulation in schizophrenia: molecular and clinical aspects of histone deacetylase inhibitors. | 2013 | Eur Arch Psychiatry Clin Neurosci | pmid:23381549 |
Rajak H et al. | Novel limonene and citral based 2,5-disubstituted-1,3,4-oxadiazoles: a natural product coupled approach to semicarbazones for antiepileptic activity. | 2013 | Bioorg. Med. Chem. Lett. | pmid:23265873 |
Koo J and Zavras A | Antiepileptic drugs (AEDs) during pregnancy and risk of congenital jaw and oral malformation. | 2013 | Oral Dis | pmid:23305414 |
Shamsi Meymandi M and Keyhanfar F | Relative potency of pregabalin, gabapentin, and morphine in a mouse model of visceral pain. | 2013 | Can J Anaesth | pmid:23132044 |
Siebel AM et al. | Antiepileptic drugs prevent changes in adenosine deamination during acute seizure episodes in adult zebrafish. | 2013 | Pharmacol. Biochem. Behav. | pmid:23287800 |
Bhattarai JP et al. | Genistein excitation of gonadotrophin-releasing hormone neurones in juvenile female mice. | 2013 | J. Neuroendocrinol. | pmid:23351167 |
Ganguly A and Lee D | Suppression of inhibitory GABAergic transmission by cAMP signaling pathway: alterations in learning and memory mutants. | 2013 | Eur. J. Neurosci. | pmid:23387411 |
Heo H et al. | Upregulation of TrkB by forskolin facilitated survival of MSC and functional recovery of memory deficient model rats. | 2013 | Biochem. Biophys. Res. Commun. | pmid:23313493 |
Anderson W et al. | Investigation of the anxiolytic effects of naringenin, a component of Mentha aquatica, in the male Sprague-Dawley rat. | 2012 Jan-Feb | Holist Nurs Pract | pmid:22157509 |
Reese EA et al. | Gabapentin's minimal action on markers of rat brain arachidonic acid metabolism agrees with its inefficacy against bipolar disorder. | 2012 Aug-Sep | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22841517 |
Arapitsas P et al. | A metabolomic approach to the study of wine micro-oxygenation. | 2012 | PLoS ONE | pmid:22662221 |
King AM et al. | 4-aminopyridine toxicity: a case report and review of the literature. | 2012 | J Med Toxicol | pmid:22782458 |
Desrues L et al. | Down-regulation of GABA(A) receptor via promiscuity with the vasoactive peptide urotensin II receptor. Potential involvement in astrocyte plasticity. | 2012 | PLoS ONE | pmid:22563490 |
McElroy SL et al. | Pharmacological management of binge eating disorder: current and emerging treatment options. | 2012 | Ther Clin Risk Manag | pmid:22654518 |
Khan I et al. | Hemichorea-hemiballismus as the presenting manifestation of nonketotic hyperglycemia in an adolescent with undiagnosed type 2 diabetes mellitus. | 2012 | Indian J Endocrinol Metab | pmid:22701838 |
Gökcan H and Konuklar FA | Theoretical study on HF elimination and aromatization mechanisms: a case of pyridoxal 5' phosphate-dependent enzyme. | 2012 | J. Org. Chem. | pmid:22646918 |
Camp BW et al. | High serum androstenedione levels correlate with impaired memory in the surgically menopausal rat: a replication and new findings. | 2012 | Eur. J. Neurosci. | pmid:22758646 |
Cserép C et al. | NMDA receptors in GABAergic synapses during postnatal development. | 2012 | PLoS ONE | pmid:22662211 |
Kamal SM | Combination of valproate and paroxetine in mice exposed to picrotoxin. | 2012 | Int J Nanomedicine | pmid:22679369 |
Nakashima T et al. | [A case of neurotoxicity reduced with pregabalin in R-CHOP chemotherapy for diffuse large B-cell lymphoma]. | 2012 | Gan To Kagaku Ryoho | pmid:22584337 |
Jeelani G et al. | Metabolic profiling of the protozoan parasite Entamoeba invadens revealed activation of unpredicted pathway during encystation. | 2012 | PLoS ONE | pmid:22662204 |
Nakashima T et al. | [A case of paclitaxel-induced peripheral neuropathy successfully treated with pregabalin]. | 2012 | Gan To Kagaku Ryoho | pmid:22996788 |
Rueda N et al. | Mouse models of Down syndrome as a tool to unravel the causes of mental disabilities. | 2012 | Neural Plast. | pmid:22685678 |
Ormerod KG et al. | Cholesterol-independent effects of methyl-β-cyclodextrin on chemical synapses. | 2012 | PLoS ONE | pmid:22590538 |
Sotoing Taïwe G et al. | Antipsychotic and sedative effects of the leaf extract of Crassocephalum bauchiense (Hutch.) Milne-Redh (Asteraceae) in rodents. | 2012 | J Ethnopharmacol | pmid:22750453 |
Wang G et al. | AMPA receptor trafficking in homeostatic synaptic plasticity: functional molecules and signaling cascades. | 2012 | Neural Plast. | pmid:22655210 |
Chaparro LE et al. | Combination pharmacotherapy for the treatment of neuropathic pain in adults. | 2012 | Cochrane Database Syst Rev | pmid:22786518 |
Newman EL et al. | Cholinergic modulation of cognitive processing: insights drawn from computational models. | 2012 | Front Behav Neurosci | pmid:22707936 |
Al-Harbi KS | Treatment-resistant depression: therapeutic trends, challenges, and future directions. | 2012 | Patient Prefer Adherence | pmid:22654508 |
Do Rego JL et al. | Regulation of neurosteroid biosynthesis by neurotransmitters and neuropeptides. | 2012 | Front Endocrinol (Lausanne) | pmid:22654849 |
Kim J et al. | Insect eggs can enhance wound response in plants: a study system of tomato Solanum lycopersicum L. and Helicoverpa zea Boddie. | 2012 | PLoS ONE | pmid:22616005 |
Tolson KP and Chappell PE | The Changes They are A-Timed: Metabolism, Endogenous Clocks, and the Timing of Puberty. | 2012 | Front Endocrinol (Lausanne) | pmid:22645521 |
Helms CM et al. | Neurosteroid influences on sensitivity to ethanol. | 2012 | Front Endocrinol (Lausanne) | pmid:22654852 |
Shalaby AM and Kamal SM | Effect of rolipram, a phosphodiesterase enzyme type-4 inhibitor, on γ-amino butyric acid content of the frontal cortex in mice exposed to chronic mild stress. | 2012 | J Pharmacol Pharmacother | pmid:22629087 |
Hansen N | Action mechanisms of transcranial direct current stimulation in Alzheimer's disease and memory loss. | 2012 | Front Psychiatry | pmid:22615703 |
Yu X et al. | Assessment of the treatment effect of baicalein on a model of Parkinsonian tremor and elucidation of the mechanism. | 2012 | Life Sci. | pmid:22634324 |
Davis MP | Drug management of visceral pain: concepts from basic research. | 2012 | Pain Res Treat | pmid:22619712 |
Ryu CH et al. | Valproic acid downregulates the expression of MGMT and sensitizes temozolomide-resistant glioma cells. | 2012 | J. Biomed. Biotechnol. | pmid:22701311 |
Wani KA et al. | D1 dopamine receptor signaling is modulated by the R7 RGS protein EAT-16 and the R7 binding protein RSBP-1 in Caenoerhabditis elegans motor neurons. | 2012 | PLoS ONE | pmid:22629462 |
Villanueva C et al. | DLK1 is a somato-dendritic protein expressed in hypothalamic arginine-vasopressin and oxytocin neurons. | 2012 | PLoS ONE | pmid:22563444 |
Å vob Å trac D et al. | The involvement of noradrenergic mechanisms in the suppressive effects of diazepam on the hypothalamic-pituitary-adrenal axis activity in female rats. | 2012 | Croat. Med. J. | pmid:22661134 |