4-aminobutyric acid

4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.

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Introduction

To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-aminobutyric acid?

4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid

MeSH term MeSH ID Detail
Duodenal Ulcer D004381 12 associated lipids
Alcoholic Intoxication D000435 15 associated lipids
Hyperkinesis D006948 11 associated lipids
Tremor D014202 15 associated lipids
Muscle Spasticity D009128 5 associated lipids
Hypothermia D007035 19 associated lipids
Parkinson Disease D010300 53 associated lipids
Down Syndrome D004314 18 associated lipids
Hypertrophy D006984 16 associated lipids
Central Nervous System Diseases D002493 10 associated lipids
Respiration Disorders D012120 5 associated lipids
Brain Diseases, Metabolic D001928 9 associated lipids
Asphyxia D001237 5 associated lipids
Heart Arrest D006323 13 associated lipids
Hepatitis A D006506 8 associated lipids
Filariasis D005368 6 associated lipids
Renal Aminoacidurias D000608 2 associated lipids
Hypokalemia D007008 6 associated lipids
Drug Eruptions D003875 30 associated lipids
Basal Ganglia Diseases D001480 8 associated lipids
Rabies D011818 4 associated lipids
Fetal Resorption D005327 15 associated lipids
Dyskinesia, Drug-Induced D004409 15 associated lipids
Ascorbic Acid Deficiency D001206 9 associated lipids
Retinal Detachment D012163 10 associated lipids
Cleft Palate D002972 9 associated lipids
Constriction, Pathologic D003251 8 associated lipids
Cerebellar Neoplasms D002528 9 associated lipids
Medulloblastoma D008527 22 associated lipids
Vitamin B 6 Deficiency D026681 10 associated lipids
Embryo Loss D020964 5 associated lipids
Neuritis D009443 4 associated lipids
Hypertension, Portal D006975 12 associated lipids
Sclerosis D012598 5 associated lipids
Amyotrophic Lateral Sclerosis D000690 11 associated lipids
Insulin Resistance D007333 99 associated lipids
Encephalitis D004660 15 associated lipids
Sarcoma, Yoshida D012517 5 associated lipids
Cerebellar Ataxia D002524 3 associated lipids
Puerperal Disorders D011644 4 associated lipids
Huntington Disease D006816 4 associated lipids
Weight Loss D015431 56 associated lipids
Tooth, Impacted D014095 9 associated lipids
Memory Disorders D008569 33 associated lipids
Parkinson Disease, Secondary D010302 17 associated lipids
Neuralgia D009437 28 associated lipids
Gingival Overgrowth D019214 7 associated lipids
Myoclonus D009207 3 associated lipids
Spinal Cord Diseases D013118 4 associated lipids
Sleep Wake Disorders D012893 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 4-aminobutyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 4-aminobutyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 4-aminobutyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-aminobutyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-aminobutyric acid

Download all related citations
Per page 10 20 50 100 | Total 40318
Authors Title Published Journal PubMed Link
Xie M et al. Gastroprotective effect of gamma-aminobutyric acid against ethanol-induced gastric mucosal injury. 2017 Chem. Biol. Interact. pmid:28456544
Malongane F et al. The synergistic potential of various teas, herbs and therapeutic drugs in health improvement: a review. 2017 J. Sci. Food Agric. pmid:28585285
Daghestani MH et al. The role of apitoxin in alleviating propionic acid-induced neurobehavioral impairments in rat pups: The expression pattern of Reelin gene. 2017 Biomed. Pharmacother. pmid:28622594
Khongrum J and Wattanathorn J Laser Acupuncture at HT7 Improves the Cerebellar Disorders in Valproic Acid-Rat Model of Autism. 2017 J Acupunct Meridian Stud pmid:28889839
Lee NK and Paik HD Bioconversion Using Lactic Acid Bacteria: Ginsenosides, GABA, and Phenolic Compounds. 2017 J. Microbiol. Biotechnol. pmid:28297748
Androsova G et al. Comparative effectiveness of antiepileptic drugs in patients with mesial temporal lobe epilepsy with hippocampal sclerosis. 2017 Epilepsia pmid:28857179
Moradi-Afrapoli F et al. HPLC-Based Activity Profiling for GABAA Receptor Modulators in Searsia pyroides Using a Larval Zebrafish Locomotor Assay. 2017 Planta Med. pmid:28511229
Nevitt SJ et al. Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data. 2017 Cochrane Database Syst Rev pmid:28661008
Lin M et al. Ergosteryl 2-naphthoate, An Ergosterol Derivative, Exhibits Antidepressant Effects Mediated by the Modification of GABAergic and Glutamatergic Systems. 2017 Molecules pmid:28362353
Cantaut-Belarif Y et al. Microglia control the glycinergic but not the GABAergic synapses via prostaglandin E2 in the spinal cord. 2017 J. Cell Biol. pmid:28716844