4-aminobutyric acid
4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
Cross Reference
Introduction
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 4-aminobutyric acid?
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
PubChem Associated disorders and diseases
What pathways are associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 4-aminobutyric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with 4-aminobutyric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 4-aminobutyric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Cotrufo R and Bonavita V | [Neurochemical and pharmacological principles in the therapy of epilepsies]. | 1976 Mar-Apr | Acta Neurol (Napoli) | pmid:1007978 |
| Subramanian P and Balamurugan E | Temporal oscillations of serum electrolytes in N-phthaloyl GABA-treated rats. | 1999 | Pharmacol. Biochem. Behav. | pmid:10080244 |
| Zahner B et al. | Once-daily versus twice-daily vigabatrin: is there a difference? The results of a double-blind pilot study. | 1999 | Epilepsia | pmid:10080511 |
| Bianchi L et al. | Simultaneous determination of basal and evoked output levels of aspartate, glutamate, taurine and 4-aminobutyric acid during microdialysis and from superfused brain slices. | 1999 | J. Chromatogr. B Biomed. Sci. Appl. | pmid:10080632 |
| Skvortsova VI et al. | [Levels of neurotransmitter amino acids in the cerebrospinal fluid of patients with acute ischemic stroke]. | 1999 | Zh Nevrol Psikhiatr Im S S Korsakova | pmid:10081133 |
| Meldrum B and Horton R | Blockade of epileptic responses in the photosensitive baboon, Papio papio, by two irreversible inhibitors of GABA-transaminase, gamma-acetylenic GABA (4-amino-hex-5-ynoic acid) and gamma-vinyl GABA (4-amino-hex-5-enoic acid). | 1978 | Psychopharmacology (Berl.) | pmid:100812 |
| Kamardin N et al. | Distinct responses of osphradial neurons to chemical stimuli and neurotransmitters in Lymnaea stagnalis L. | 1999 | Cell. Mol. Neurobiol. | pmid:10081607 |
| Honjo K et al. | GABA may function tonically via GABA(A) receptors to inhibit hypotension and bradycardia by L-DOPA microinjected into depressor sites of the nucleus tractus solitarii in anesthetized rats. | 1999 | Neurosci. Lett. | pmid:10081935 |
| Goshima Y et al. | The evidence for tonic GABAergic regulation of basal L-DOPA release via activation of inhibitory GABA(A) receptors in the nucleus tractus solitarii of anesthetized rats. | 1999 | Neurosci. Lett. | pmid:10081972 |
| Bloms-Funke P et al. | Extracellular single-unit recordings of piriform cortex neurons in rats: influence of different types of anesthesia and characterization of neurons by pharmacological manipulation of serotonin receptors. | 1999 | J. Neurosci. Res. | pmid:10082083 |