4-aminobutyric acid

4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.

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Introduction

To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-aminobutyric acid?

4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid

MeSH term MeSH ID Detail
Herpes Simplex D006561 3 associated lipids
Movement Disorders D009069 3 associated lipids
Tourette Syndrome D005879 3 associated lipids
Polyneuropathies D011115 3 associated lipids
Psychomotor Agitation D011595 3 associated lipids
Muscle Cramp D009120 3 associated lipids
Dystonia D004421 3 associated lipids
Neuroaxonal Dystrophies D019150 3 associated lipids
Porphyria, Acute Intermittent D017118 3 associated lipids
Puerperal Disorders D011644 4 associated lipids
Vertigo D014717 4 associated lipids
Neuritis D009443 4 associated lipids
Reflex Sympathetic Dystrophy D012019 4 associated lipids
Huntington Disease D006816 4 associated lipids
Spinal Cord Diseases D013118 4 associated lipids
Neuroendocrine Tumors D018358 4 associated lipids
Genetic Diseases, Inborn D030342 4 associated lipids
Hyperglycemic Hyperosmolar Nonketotic Coma D006944 4 associated lipids
Retrograde Degeneration D012183 4 associated lipids
Rabies D011818 4 associated lipids
Pain, Intractable D010148 4 associated lipids
Muscle Rigidity D009127 4 associated lipids
Newcastle Disease D009521 4 associated lipids
Mercury Poisoning D008630 4 associated lipids
Tinnitus D014012 4 associated lipids
Epilepsy, Temporal Lobe D004833 4 associated lipids
Confusion D003221 4 associated lipids
Granuloma, Foreign-Body D015745 5 associated lipids
Embryo Loss D020964 5 associated lipids
Asthenia D001247 5 associated lipids
Skin Diseases, Vesiculobullous D012872 5 associated lipids
Epilepsy, Reflex D020195 5 associated lipids
Hypoxia, Brain D002534 5 associated lipids
Sclerosis D012598 5 associated lipids
Respiration Disorders D012120 5 associated lipids
Epilepsy, Absence D004832 5 associated lipids
Hyperammonemia D022124 5 associated lipids
Sleep Deprivation D012892 5 associated lipids
Asphyxia D001237 5 associated lipids
Diabetes Insipidus D003919 5 associated lipids
Muscle Spasticity D009128 5 associated lipids
Cushing Syndrome D003480 5 associated lipids
Sarcoma, Yoshida D012517 5 associated lipids
Opioid-Related Disorders D009293 5 associated lipids
Supranuclear Palsy, Progressive D013494 5 associated lipids
Filariasis D005368 6 associated lipids
Hypokalemia D007008 6 associated lipids
Brain Damage, Chronic D001925 6 associated lipids
Fetal Alcohol Spectrum Disorders D063647 6 associated lipids
Gingival Overgrowth D019214 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 4-aminobutyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 4-aminobutyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 4-aminobutyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-aminobutyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-aminobutyric acid

Download all related citations
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Authors Title Published Journal PubMed Link
Gonzalez LE et al. Stimulation of benzodiazepine receptors in the dorsal hippocampus and median raphé reveals differential GABAergic control in two animal tests of anxiety. 1998 Eur. J. Neurosci. pmid:9875346
Pernberg J et al. Structure and dynamics of receptive fields in the visual cortex of the cat (area 18) and the influence of GABAergic inhibition. 1998 Eur. J. Neurosci. pmid:9875339
Wickelgren I Drug may suppress the craving for nicotine. 1998 Science pmid:9874627
Czupryn A et al. Neurotransmitter system markers in adult barrel field. 1998 Somatosens Mot Res pmid:9874522
Kogo M et al. Examination of the relationships between jaw opener and closer rhythmical muscle activity in an in vitro brainstem jaw-attached preparation. 1998 Somatosens Mot Res pmid:9874519
Bonanno G et al. GABA(B) receptors as potential targets for drugs able to prevent excessive excitatory amino acid transmission in the spinal cord. 1998 Eur. J. Pharmacol. pmid:9874164
McGraw T and Stacey BR Gabapentin for treatment of neuropathic pain in a 12-year-old girl. 1998 Clin J Pain pmid:9874016
Carruthers NI et al. Synthesis of a series of sulfinic acid analogs of GABA and evaluation of their GABAB receptor affinities. 1998 Bioorg. Med. Chem. Lett. pmid:9873676
Serfass L and Casara PJ General synthesis of 3-substituted alkenyl GABA as potential anticonvulsants. 1998 Bioorg. Med. Chem. Lett. pmid:9873588
Bernstein EM and Quick MW Regulation of gamma-aminobutyric acid (GABA) transporters by extracellular GABA. 1999 J. Biol. Chem. pmid:9873028