4-aminobutyric acid

4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.

Cross Reference

Introduction

To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-aminobutyric acid?

4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid

MeSH term MeSH ID Detail
Herpes Simplex D006561 3 associated lipids
Hiccup D006606 1 associated lipids
High Pressure Neurological Syndrome D006610 1 associated lipids
Huntington Disease D006816 4 associated lipids
Hyperalgesia D006930 42 associated lipids
Hyperemia D006940 25 associated lipids
Hyperglycemia D006943 21 associated lipids
Hyperglycemic Hyperosmolar Nonketotic Coma D006944 4 associated lipids
Hyperkinesis D006948 11 associated lipids
Hyperlipidemias D006949 73 associated lipids
Hypernatremia D006955 1 associated lipids
Hyperphagia D006963 3 associated lipids
Hyperplasia D006965 34 associated lipids
Hypertension D006973 115 associated lipids
Hypertension, Portal D006975 12 associated lipids
Hyperthyroidism D006980 12 associated lipids
Hypertrophy D006984 16 associated lipids
Hypocalcemia D006996 12 associated lipids
Hypokalemia D007008 6 associated lipids
Hypoparathyroidism D007011 2 associated lipids
Hypophosphatasia D007014 1 associated lipids
Hypotension D007022 41 associated lipids
Hypotension, Orthostatic D007024 3 associated lipids
Hypothermia D007035 19 associated lipids
Hypothyroidism D007037 32 associated lipids
Iatrogenic Disease D007049 1 associated lipids
Illusions D007088 1 associated lipids
Inflammation D007249 119 associated lipids
Insulin Resistance D007333 99 associated lipids
Insulinoma D007340 28 associated lipids
Ischemia D007511 18 associated lipids
Adenoma, Islet Cell D007516 7 associated lipids
Creutzfeldt-Jakob Syndrome D007562 7 associated lipids
Ketosis D007662 13 associated lipids
Kidney Diseases D007674 29 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Kidney Neoplasms D007680 29 associated lipids
Liver Cirrhosis, Alcoholic D008104 17 associated lipids
Lung Neoplasms D008175 171 associated lipids
Magnesium Deficiency D008275 9 associated lipids
alpha-Mannosidosis D008363 1 associated lipids
Medulloblastoma D008527 22 associated lipids
Meige Syndrome D008538 1 associated lipids
Melkersson-Rosenthal Syndrome D008556 2 associated lipids
Memory Disorders D008569 33 associated lipids
Meningioma D008579 11 associated lipids
Meningitis, Aseptic D008582 1 associated lipids
Meningitis, Viral D008587 1 associated lipids
Intellectual Disability D008607 13 associated lipids
Mercury Poisoning D008630 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 4-aminobutyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 4-aminobutyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 4-aminobutyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-aminobutyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-aminobutyric acid

Download all related citations
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Authors Title Published Journal PubMed Link
Guptill JT et al. Patient demographics and health plan paid costs in chronic inflammatory demyelinating polyneuropathy. 2014 Muscle Nerve pmid:24639235
Park SA et al. Kinetic characterization and molecular modeling of NAD(P)(+)-dependent succinic semialdehyde dehydrogenase from Bacillus subtilis as an ortholog YneI. 2014 J. Microbiol. Biotechnol. pmid:24809290
Bailey JN et al. Hypothesis-independent pathway analysis implicates GABA and acetyl-CoA metabolism in primary open-angle glaucoma and normal-pressure glaucoma. 2014 Hum. Genet. pmid:25037249
Pollock E et al. Metalloproteinase inhibition prevents inhibitory synapse reorganization and seizure genesis. 2014 Neurobiol. Dis. pmid:24946277
Blake CB and Smith BN cAMP-dependent insulin modulation of synaptic inhibition in neurons of the dorsal motor nucleus of the vagus is altered in diabetic mice. 2014 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:24990858
Liu ZP et al. Chronic stress impairs GABAergic control of amygdala through suppressing the tonic GABAA receptor currents. 2014 Mol Brain pmid:24758222
Ikeda K et al. Gas chromatography-electron ionization-mass spectrometry quantitation of valproic acid and gabapentin, using dried plasma spots, for therapeutic drug monitoring in in-home medical care. 2014 Biomed. Chromatogr. pmid:24889681
Kumamaru E et al. Valproic acid selectively suppresses the formation of inhibitory synapses in cultured cortical neurons. 2014 Neurosci. Lett. pmid:24708928
Wilkins HM et al. Oxaloacetate activates brain mitochondrial biogenesis, enhances the insulin pathway, reduces inflammation and stimulates neurogenesis. 2014 Hum. Mol. Genet. pmid:25027327
Marahatta A et al. Soybean greatly reduces valproic acid plasma concentrations: a food-drug interaction study. 2014 Sci Rep pmid:24618639