4-aminobutyric acid

4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.

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Introduction

To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-aminobutyric acid?

4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid

MeSH term MeSH ID Detail
Parkinson Disease D010300 53 associated lipids
Bulbar Palsy, Progressive D010244 1 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Pain, Postoperative D010149 13 associated lipids
Pain, Intractable D010148 4 associated lipids
Pain D010146 64 associated lipids
Olivopontocerebellar Atrophies D009849 2 associated lipids
Occupational Diseases D009784 42 associated lipids
Obesity D009765 29 associated lipids
Newcastle Disease D009521 4 associated lipids
Neuritis D009443 4 associated lipids
Neuralgia D009437 28 associated lipids
Nervous System Diseases D009422 37 associated lipids
Nervous System Malformations D009421 1 associated lipids
Nerve Degeneration D009410 53 associated lipids
Nelson Syndrome D009347 1 associated lipids
Opioid-Related Disorders D009293 5 associated lipids
Myofascial Pain Syndromes D009209 1 associated lipids
Myoclonus D009207 3 associated lipids
Muscular Diseases D009135 7 associated lipids
Muscle Spasticity D009128 5 associated lipids
Muscle Rigidity D009127 4 associated lipids
Muscle Hypertonia D009122 1 associated lipids
Muscle Cramp D009120 3 associated lipids
Multiple Sclerosis D009103 13 associated lipids
Movement Disorders D009069 3 associated lipids
Motion Sickness D009041 1 associated lipids
Morphine Dependence D009021 9 associated lipids
Mitral Valve Prolapse D008945 1 associated lipids
Migraine Disorders D008881 11 associated lipids
Mercury Poisoning D008630 4 associated lipids
Intellectual Disability D008607 13 associated lipids
Meningitis, Viral D008587 1 associated lipids
Meningitis, Aseptic D008582 1 associated lipids
Meningioma D008579 11 associated lipids
Memory Disorders D008569 33 associated lipids
Melkersson-Rosenthal Syndrome D008556 2 associated lipids
Meige Syndrome D008538 1 associated lipids
Medulloblastoma D008527 22 associated lipids
alpha-Mannosidosis D008363 1 associated lipids
Magnesium Deficiency D008275 9 associated lipids
Lung Neoplasms D008175 171 associated lipids
Liver Cirrhosis, Alcoholic D008104 17 associated lipids
Kidney Neoplasms D007680 29 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Kidney Diseases D007674 29 associated lipids
Ketosis D007662 13 associated lipids
Creutzfeldt-Jakob Syndrome D007562 7 associated lipids
Adenoma, Islet Cell D007516 7 associated lipids
Ischemia D007511 18 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 4-aminobutyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 4-aminobutyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 4-aminobutyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-aminobutyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-aminobutyric acid

Download all related citations
Per page 10 20 50 100 | Total 40318
Authors Title Published Journal PubMed Link
Xu Z et al. From the Cover: Functional Analysis Reveals Glutamate and Gamma-Aminobutyric Acid-Gated Chloride Channels as Targets of Avermectins in the Carmine Spider Mite. 2017 Toxicol. Sci. pmid:27742867
Turner DP et al. Using a graphical risk tool to examine willingness to take migraine prophylactic medications. 2016 Pain pmid:27820159
Smetana KS et al. Antiepileptic dosing for critically ill adult patients receiving renal replacement therapy. 2016 J Crit Care pmid:27546759
Lai EC et al. Comparative persistence of antiepileptic drugs in patients with epilepsy: A STROBE-compliant retrospective cohort study. 2016 Medicine (Baltimore) pmid:27583857
Motoyama K et al. Cholesterol-Lowering Effect of Octaarginine-Appended β-Cyclodextrin in Npc1-Trap-CHO Cells. 2016 Biol. Pharm. Bull. pmid:27601082
Setoyama D et al. Plasma Metabolites Predict Severity of Depression and Suicidal Ideation in Psychiatric Patients-A Multicenter Pilot Analysis. 2016 PLoS ONE pmid:27984586
Donvito G et al. Palmitoylethanolamide Reverses Paclitaxel-Induced Allodynia in Mice. 2016 J. Pharmacol. Exp. Ther. pmid:27608657
Kantrowitz JT et al. d-Cycloserine, an NMDA Glutamate Receptor Glycine Site Partial Agonist, Induces Acute Increases in Brain Glutamate Plus Glutamine and GABA Comparable to Ketamine. 2016 Am J Psychiatry pmid:27903101
Mettang T Uremic Itch Management. 2016 Curr. Probl. Dermatol. pmid:27578082
Dadsetan S et al. Infliximab reduces peripheral inflammation, neuroinflammation, and extracellular GABA in the cerebellum and improves learning and motor coordination in rats with hepatic encephalopathy. 2016 J Neuroinflammation pmid:27623772