4-aminobutyric acid

4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.

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Introduction

To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-aminobutyric acid?

4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid

MeSH term MeSH ID Detail
Duodenal Ulcer D004381 12 associated lipids
Alcoholic Intoxication D000435 15 associated lipids
Hyperkinesis D006948 11 associated lipids
Tremor D014202 15 associated lipids
Muscle Spasticity D009128 5 associated lipids
Hypothermia D007035 19 associated lipids
Parkinson Disease D010300 53 associated lipids
Down Syndrome D004314 18 associated lipids
Hypertrophy D006984 16 associated lipids
Central Nervous System Diseases D002493 10 associated lipids
Respiration Disorders D012120 5 associated lipids
Brain Diseases, Metabolic D001928 9 associated lipids
Asphyxia D001237 5 associated lipids
Heart Arrest D006323 13 associated lipids
Hepatitis A D006506 8 associated lipids
Filariasis D005368 6 associated lipids
Renal Aminoacidurias D000608 2 associated lipids
Hypokalemia D007008 6 associated lipids
Drug Eruptions D003875 30 associated lipids
Basal Ganglia Diseases D001480 8 associated lipids
Rabies D011818 4 associated lipids
Fetal Resorption D005327 15 associated lipids
Dyskinesia, Drug-Induced D004409 15 associated lipids
Ascorbic Acid Deficiency D001206 9 associated lipids
Retinal Detachment D012163 10 associated lipids
Cleft Palate D002972 9 associated lipids
Constriction, Pathologic D003251 8 associated lipids
Cerebellar Neoplasms D002528 9 associated lipids
Medulloblastoma D008527 22 associated lipids
Vitamin B 6 Deficiency D026681 10 associated lipids
Embryo Loss D020964 5 associated lipids
Neuritis D009443 4 associated lipids
Hypertension, Portal D006975 12 associated lipids
Sclerosis D012598 5 associated lipids
Amyotrophic Lateral Sclerosis D000690 11 associated lipids
Insulin Resistance D007333 99 associated lipids
Encephalitis D004660 15 associated lipids
Sarcoma, Yoshida D012517 5 associated lipids
Cerebellar Ataxia D002524 3 associated lipids
Puerperal Disorders D011644 4 associated lipids
Huntington Disease D006816 4 associated lipids
Weight Loss D015431 56 associated lipids
Tooth, Impacted D014095 9 associated lipids
Memory Disorders D008569 33 associated lipids
Parkinson Disease, Secondary D010302 17 associated lipids
Neuralgia D009437 28 associated lipids
Gingival Overgrowth D019214 7 associated lipids
Myoclonus D009207 3 associated lipids
Spinal Cord Diseases D013118 4 associated lipids
Sleep Wake Disorders D012893 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 4-aminobutyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 4-aminobutyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 4-aminobutyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-aminobutyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-aminobutyric acid

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Authors Title Published Journal PubMed Link
Xu Z et al. From the Cover: Functional Analysis Reveals Glutamate and Gamma-Aminobutyric Acid-Gated Chloride Channels as Targets of Avermectins in the Carmine Spider Mite. 2017 Toxicol. Sci. pmid:27742867
Turner DP et al. Using a graphical risk tool to examine willingness to take migraine prophylactic medications. 2016 Pain pmid:27820159
Smetana KS et al. Antiepileptic dosing for critically ill adult patients receiving renal replacement therapy. 2016 J Crit Care pmid:27546759
Lai EC et al. Comparative persistence of antiepileptic drugs in patients with epilepsy: A STROBE-compliant retrospective cohort study. 2016 Medicine (Baltimore) pmid:27583857
Motoyama K et al. Cholesterol-Lowering Effect of Octaarginine-Appended β-Cyclodextrin in Npc1-Trap-CHO Cells. 2016 Biol. Pharm. Bull. pmid:27601082
Setoyama D et al. Plasma Metabolites Predict Severity of Depression and Suicidal Ideation in Psychiatric Patients-A Multicenter Pilot Analysis. 2016 PLoS ONE pmid:27984586
Donvito G et al. Palmitoylethanolamide Reverses Paclitaxel-Induced Allodynia in Mice. 2016 J. Pharmacol. Exp. Ther. pmid:27608657
Kantrowitz JT et al. d-Cycloserine, an NMDA Glutamate Receptor Glycine Site Partial Agonist, Induces Acute Increases in Brain Glutamate Plus Glutamine and GABA Comparable to Ketamine. 2016 Am J Psychiatry pmid:27903101
Mettang T Uremic Itch Management. 2016 Curr. Probl. Dermatol. pmid:27578082
Dadsetan S et al. Infliximab reduces peripheral inflammation, neuroinflammation, and extracellular GABA in the cerebellum and improves learning and motor coordination in rats with hepatic encephalopathy. 2016 J Neuroinflammation pmid:27623772