| MeSH term | MeSH ID | Detail |
|---|---|---|
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Diabetic Retinopathy | D003930 | 39 associated lipids |
| Ketosis | D007662 | 13 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Stomach Neoplasms | D013274 | 24 associated lipids |
| Arthritis | D001168 | 41 associated lipids |
| Arthritis, Experimental | D001169 | 24 associated lipids |
| Hypotension | D007022 | 41 associated lipids |
| Coronary Disease | D003327 | 70 associated lipids |
4-aminobutyric acid
4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
Cross Reference
Introduction
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 4-aminobutyric acid?
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
PubChem Associated disorders and diseases
What pathways are associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 4-aminobutyric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 4-aminobutyric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 4-aminobutyric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Tietz EI et al. | Functional GABAA receptor heterogeneity of acutely dissociated hippocampal CA1 pyramidal cells. | 1999 | J. Neurophysiol. | pmid:10200193 |
| Petty CN and Lucero MT | Characterization of a Na+-dependent betaine transporter with Cl- channel properties in squid motor neurons. | 1999 | J. Neurophysiol. | pmid:10200192 |
| Steele PM and Mauk MD | Inhibitory control of LTP and LTD: stability of synapse strength. | 1999 | J. Neurophysiol. | pmid:10200191 |
| Hu HZ et al. | Enhancement of GABA-activated current by muscarine in rat dorsal root ganglion neurons. | 1999 | Neuroscience | pmid:10199621 |
| Celada P et al. | GABAergic control of rat substantia nigra dopaminergic neurons: role of globus pallidus and substantia nigra pars reticulata. | 1999 | Neuroscience | pmid:10199615 |
| Paladini CA et al. | Striatal, pallidal, and pars reticulata evoked inhibition of nigrostriatal dopaminergic neurons is mediated by GABA(A) receptors in vivo. | 1999 | Neuroscience | pmid:10199614 |
| Gironell A et al. | A randomized placebo-controlled comparative trial of gabapentin and propranolol in essential tremor. | 1999 | Arch. Neurol. | pmid:10199338 |
| Hebeiss K and Kilbinger H | Cholinergic and GABAergic regulation of nitric oxide synthesis in the guinea pig ileum. | 1999 | Am. J. Physiol. | pmid:10198328 |
| Ferry B et al. | Functional interaction between entorhinal cortex and basolateral amygdala during trace conditioning of odor aversion in the rat. | 1999 | Behav. Neurosci. | pmid:10197911 |
| Rehman HU | Stiff-man syndrome. | 1998 | Postgrad Med J | pmid:10197191 |
| Cook PB and McReynolds JS | Lateral inhibition in the inner retina is important for spatial tuning of ganglion cells. | 1998 | Nat. Neurosci. | pmid:10196588 |
| Betz H | Gephyrin, a major player in GABAergic postsynaptic membrane assembly? | 1998 | Nat. Neurosci. | pmid:10196557 |
| Mody I | Interneurons and the ghost of the sea. | 1998 | Nat. Neurosci. | pmid:10196538 |
| Koutsilieri E et al. | Involvement of microglia in cerebrospinal fluid glutamate increase in SIV-infected rhesus monkeys (Macaca mulatta). | 1999 | AIDS Res. Hum. Retroviruses | pmid:10195757 |
| Weber OM et al. | Effects of vigabatrin intake on brain GABA activity as monitored by spectrally edited magnetic resonance spectroscopy and positron emission tomography. | 1999 | Magn Reson Imaging | pmid:10195585 |
| Jo YH and Schlichter R | Synaptic corelease of ATP and GABA in cultured spinal neurons. | 1999 | Nat. Neurosci. | pmid:10195216 |
| Chang Y and Weiss DS | Channel opening locks agonist onto the GABAC receptor. | 1999 | Nat. Neurosci. | pmid:10195213 |
| Colquhoun D | GABA and the single oocyte: relating binding to gating. | 1999 | Nat. Neurosci. | pmid:10195208 |
| Salter MW and De Koninck Y | An ambiguous fast synapse: a new twist in the tale of two transmitters. | 1999 | Nat. Neurosci. | pmid:10195207 |
| Reyes A et al. | Target-cell-specific facilitation and depression in neocortical circuits. | 1998 | Nat. Neurosci. | pmid:10195160 |
| McDonald BJ et al. | Adjacent phosphorylation sites on GABAA receptor beta subunits determine regulation by cAMP-dependent protein kinase. | 1998 | Nat. Neurosci. | pmid:10195104 |
| Gribkoff VK et al. | A reexamination of the role of GABA in the mammalian suprachiasmatic nucleus. | 1999 | J. Biol. Rhythms | pmid:10194649 |
| Eriksson AS and O'Connor WT | Analysis of CSF amino acids in young patients with generalised refractory epilepsy during an add-on study with lamotrigine. | 1999 | Epilepsy Res. | pmid:10194115 |
| Fukami S et al. | The effects of a point mutation of the beta2 subunit of GABA(A) receptor on direct and modulatory actions of general anesthetics. | 1999 | Eur. J. Pharmacol. | pmid:10193664 |
| Ipponi A et al. | Tiagabine antinociception in rodents depends on GABA(B) receptor activation: parallel antinociception testing and medial thalamus GABA microdialysis. | 1999 | Eur. J. Pharmacol. | pmid:10193656 |
| Maloney KJ et al. | Differential c-Fos expression in cholinergic, monoaminergic, and GABAergic cell groups of the pontomesencephalic tegmentum after paradoxical sleep deprivation and recovery. | 1999 | J. Neurosci. | pmid:10191323 |
| Milner LD and Landmesser LT | Cholinergic and GABAergic inputs drive patterned spontaneous motoneuron activity before target contact. | 1999 | J. Neurosci. | pmid:10191318 |
| Miller RG | Carrell-Krusen Symposium invited lecture. Clinical trials in motor neuron diseases. | 1999 | J. Child Neurol. | pmid:10190269 |
| Fukunaga A et al. | Insecticidal properties of 3-aminopropyl(methyl)phosphinic acid and its effect on K(+)-evoked release of acetylcholine from cockroach synaptosomes. | 1999 | Comp. Biochem. Physiol. C, Pharmacol. Toxicol. Endocrinol. | pmid:10190056 |
| Bryans JS and Wustrow DJ | 3-substituted GABA analogs with central nervous system activity: a review. | 1999 | Med Res Rev | pmid:10189176 |
| Xu TL | Gamma-aminobutyric acid-induced responses in acutely dissociated neurons from the rat sacral dorsal commissural nucleus. | 1999 | J. Auton. Nerv. Syst. | pmid:10189117 |
| Calabresi P et al. | An in vitro electrophysiological study on the effects of phenytoin, lamotrigine and gabapentin on striatal neurons. | 1999 | Br. J. Pharmacol. | pmid:10188980 |
| Yajima Y and Hayashi Y | Ambiguous respiratory neurons are modulated by GABA(A) receptor-mediated inhibition. | 1999 | Neuroscience | pmid:10188951 |
| Kalyuzhny AE and Wessendorf MW | Serotonergic and GABAergic neurons in the medial rostral ventral medulla express kappa-opioid receptor immunoreactivity. | 1999 | Neuroscience | pmid:10188949 |
| Matuszewich L and Yamamoto BK | Modulation of GABA release by dopamine in the substantia nigra. | 1999 | Synapse | pmid:10188635 |
| Sohn J and Yoon YH | Iron-induced cytotoxicity in cultured rat retinal neurons. | 1998 | Korean J Ophthalmol | pmid:10188366 |
| Vigabatrin: new indication. An advance in infantile spasms. | 1998 | Prescrire Int | pmid:10183381 | |
| Assumçrao JA et al. | A superfusion technique for isotope efflux studies and concurrent electrophysiological investigation in the rat cuneate nucleus [proceedings]. | 1976 | J. Physiol. (Lond.) | pmid:1018233 |
| Gallager DW and Aghajanian GK | Effect of antipsychotic drugs on the firing of dorsal raphe cells. II. Reversal by picrotoxin. | 1976 | Eur. J. Pharmacol. | pmid:10174 |
| Kovalev GV et al. | [Participation of GABA and glycine in the formation of somato-sympathetic reflexes]. | 1976 | Biull Eksp Biol Med | pmid:1016716 |
| Reinharz D et al. | The economic effects of introducing vigabatrin, a new antiepileptic medication. | 1995 | Pharmacoeconomics | pmid:10160074 |
| Sharma RP et al. | Toxic, neurochemical and behavioral effects of dieldrin exposure in mallard ducks. | 1976 | Arch. Environ. Contam. Toxicol. | pmid:1015862 |
| Casacchia M et al. | [Directed therapy of Parkinson's disease. Clinical evaluations and pharmacological choice]. | 1976 May-Jun | Acta Neurol (Napoli) | pmid:1015365 |
| Konitzer K and Voigt S | [Glucose metabolism in different regions of the rat brain under hypokinetic stress influence]. | 1976 | Acta Biol. Med. Ger. | pmid:1015163 |
| Schober W and Guss H | [Treatment of forced weeping (author's transl)]. | 1976 | Wien. Klin. Wochenschr. | pmid:1014709 |
| Kataoka K et al. | Regional and subcellular distribution of gold in brain of gold thioglucose obese mouse. | 1978 May-Jun | Brain Res. Bull. | pmid:101285 |
| Soubrié P et al. | Antagonism of diazepam against central anticholinergic drug-induced hyperactivity in mice: involvement of a GABA mechanism. | 1976 | Neuropharmacology | pmid:1012442 |
| Izuno Y | Effect of methylmercuric chloride on metabolism of the GABA shunt in rat brain. | 1976 | Kumamoto Med J | pmid:1011792 |
| Blaustein MP and King AC | Influence of membrane potential on the sodium-dependent uptake of gamma-aminobutyric acid by presynaptic nerve terminals: experimental observations and theoretical considerations. | 1976 | J. Membr. Biol. | pmid:1011247 |
| pmid:10103096 | ||||
| pmid:10103070 | ||||
| pmid:10102500 | ||||
| pmid:10101733 | ||||
| Huang RQ et al. | The tyrosine kinase inhibitor genistein directly inhibits GABAA receptors. | 1999 | Brain Res. Mol. Brain Res. | pmid:10101245 |
| pmid:10101240 | ||||
| Veggiotti P et al. | Vigabatrin use in psychotic epileptic patients: report of a prospective pilot study. | 1999 | Acta Neurol. Scand. | pmid:10100956 |
| Ruzhinskaia NN | [Receptor responses to amino acids recorded from the surface of the olfactory bulb]. | 1976 | Fiziol Zh SSSR Im I M Sechenova | pmid:1010066 |
| Hammond JB and Ahmad F | Hepatic encephalopathy and role of antibenzodiazepines. | 1998 | Am J Ther | pmid:10099035 |
| Ros-Moreno RM et al. | Interaction of ivermectin with gamma-aminobutyric acid receptors in Trichinella spiralis muscle larvae. | 1999 | Parasitol. Res. | pmid:10099015 |
| Reynolds GP et al. | Brain neurotransmitter deficits in mice transgenic for the Huntington's disease mutation. | 1999 | J. Neurochem. | pmid:10098889 |
| Vadivelu N and Berger J | Neuropathic pain after anti-HIV gene therapy successfully treated with gabapentin. | 1999 | J Pain Symptom Manage | pmid:10098357 |
| Leigh RJ and Ramat S | Neuropharmacologic aspects of the ocular motor system and the treatment of abnormal eye movements. | 1999 | Curr. Opin. Neurol. | pmid:10097880 |
| Berkley KJ | Sex differences in pain. | 1997 | Behav Brain Sci | pmid:10097000 |
| Pencheva N et al. | Comparison of gamma-aminobutyric acid effects in different parts of the cat ileum. | 1999 | Eur. J. Pharmacol. | pmid:10096769 |
| Kurozumi Y et al. | Experimental beta-alaninuria induced by (aminooxy)acetate. | 1999 | Acta Med. Okayama | pmid:10096733 |
| Gonçalves PP et al. | Regulation of the gamma-aminobutyric acid transporter activity by protein phosphatases in synaptic plasma membranes. | 1999 | Neurosci. Res. | pmid:10096470 |
| Kitahara T et al. | Molecular mechanisms of vestibular compensation in the central vestibular system--review. | 1998 | Acta Otolaryngol Suppl | pmid:10095856 |
| Feng L et al. | Differential effects of GDNF and BDNF on cultured ventral mesencephalic neurons. | 1999 | Brain Res. Mol. Brain Res. | pmid:10095078 |
| Hylland P and Nilsson GE | Extracellular levels of amino acid neurotransmitters during anoxia and forced energy deficiency in crucian carp brain. | 1999 | Brain Res. | pmid:10095011 |
| Yoon YH et al. | High vulnerability of GABA-immunoreactive neurons to kainate in rat retinal cultures: correlation with the kainate-stimulated cobalt uptake. | 1999 | Brain Res. | pmid:10095009 |
| Stringer JL and Lorenzo N | The reduction in paired-pulse inhibition in the rat hippocampus by gabapentin is independent of GABA(B) receptor receptor activation. | 1999 | Epilepsy Res. | pmid:10094428 |
| Deschenes M and Feltz P | GABA-induced rise of extracellular potassium in rat dorsal root ganglia: an electrophysiological study in vivo. | 1976 | Brain Res. | pmid:1009435 |
| Deschenes M et al. | A model for an estimate in vivo of the ionic basis of presynaptic inhibition: an intracellular analysis of the GABA-induced depolarization in rat dorsal root ganglia. | 1976 | Brain Res. | pmid:1009434 |
| Coyle JT and Yamamura HI | Neurochemical aspects of the ontogenesis of cholinergic neurons in the rat brain. | 1976 | Brain Res. | pmid:1009427 |
| Mata MM et al. | On GABA function and physiology in the pineal gland. | 1976 | Brain Res. | pmid:1009426 |
| Rosina A et al. | GAT-1 developmental expression in the rat cerebellar cortex: basket and pinceau formation. | 1999 | Neuroreport | pmid:10094127 |
| pmid:10091848 | ||||
| Jóźwiak L et al. | Behavioral studies of the effects of moderate oligemic hypoxia caused by bilateral clamping of carotid arteries in mice. Impairment of spatial working memory. | 1998 Jul-Oct | Pol J Pharmacol | pmid:10091712 |
| Möck M et al. | GABAergic inhibition in the rat pontine nuclei is exclusively extrinsic: evidence from an in situ hybridization study for GAD67 mRNA. | 1999 | Exp Brain Res | pmid:10090666 |
| Rogers HJ and Lietman PS | Inhibition by trimethoprim of some effects of epidermal growth factor on human fibroblasts in tissue culture. | 1976 | Biochem. Pharmacol. | pmid:1008900 |
| Ferraro L et al. | The vigilance promoting drug modafinil increases extracellular glutamate levels in the medial preoptic area and the posterior hypothalamus of the conscious rat: prevention by local GABAA receptor blockade. | 1999 | Neuropsychopharmacology | pmid:10088135 |
| Brussaard AB et al. | Changes in properties and neurosteroid regulation of GABAergic synapses in the supraoptic nucleus during the mammalian female reproductive cycle. | 1999 | J. Physiol. (Lond.) | pmid:10087349 |
| Alkondon M et al. | Choline and selective antagonists identify two subtypes of nicotinic acetylcholine receptors that modulate GABA release from CA1 interneurons in rat hippocampal slices. | 1999 | J. Neurosci. | pmid:10087082 |
| Polgár E et al. | GABAergic neurons that contain neuropeptide Y selectively target cells with the neurokinin 1 receptor in laminae III and IV of the rat spinal cord. | 1999 | J. Neurosci. | pmid:10087077 |
| Verheugen JA et al. | Noninvasive measurements of the membrane potential and GABAergic action in hippocampal interneurons. | 1999 | J. Neurosci. | pmid:10087068 |
| Mozrzymas JW et al. | Chlorpromazine inhibits miniature GABAergic currents by reducing the binding and by increasing the unbinding rate of GABAA receptors. | 1999 | J. Neurosci. | pmid:10087062 |
| Seidl JJ and Slawson JG | Gabapentin for painful diabetic neuropathy. | 1999 | J Fam Pract | pmid:10086757 |
| Subramanian P et al. | Temporal oscillations of phosphatases in N-phthaloyl gamma-aminobutyric acid treated rats. | 1998 | Indian J. Exp. Biol. | pmid:10085783 |
| Jensen K et al. | Role of presynaptic L-type Ca2+ channels in GABAergic synaptic transmission in cultured hippocampal neurons. | 1999 | J. Neurophysiol. | pmid:10085349 |
| Lin Q et al. | Inhibition of primate spinothalamic tract neurons by spinal glycine and GABA is modulated by guanosine 3',5'-cyclic monophosphate. | 1999 | J. Neurophysiol. | pmid:10085336 |
| Dvorak-Carbone H and Schuman EM | Long-term depression of temporoammonic-CA1 hippocampal synaptic transmission. | 1999 | J. Neurophysiol. | pmid:10085331 |
| Kiyatkin EA and Rebec GV | Modulation of striatal neuronal activity by glutamate and GABA: iontophoresis in awake, unrestrained rats. | 1999 | Brain Res. | pmid:10082887 |
| Maitra R and Reynolds JN | Subunit dependent modulation of GABAA receptor function by neuroactive steroids. | 1999 | Brain Res. | pmid:10082863 |
| Messier C et al. | Contribution of cholinergic and gabaergic functions to memory processes in BALB/cANnCrlBR mice. | 1999 | Brain Res. | pmid:10082853 |
| Koo B | Vigabatrin in the treatment of infantile spasms. | 1999 | Pediatr. Neurol. | pmid:10082337 |
| Mäkelä R et al. | Loreclezole and La3+ differentiate cerebellar granule cell GABA(A) receptor subtypes. | 1999 | Eur. J. Pharmacol. | pmid:10082271 |
| Rezayat M et al. | Effects of CCK antagonists on GABA mechanism-induced antinociception in the formalin test. | 1999 | Eur Neuropsychopharmacol | pmid:10082222 |
| Biswas B and Carlsson A | Effect of intraperitoneally administered GABA on the locomotor activity of mice. | 1978 | Psychopharmacology (Berl.) | pmid:100821 |
| Bloms-Funke P et al. | Extracellular single-unit recordings of piriform cortex neurons in rats: influence of different types of anesthesia and characterization of neurons by pharmacological manipulation of serotonin receptors. | 1999 | J. Neurosci. Res. | pmid:10082083 |
| Goshima Y et al. | The evidence for tonic GABAergic regulation of basal L-DOPA release via activation of inhibitory GABA(A) receptors in the nucleus tractus solitarii of anesthetized rats. | 1999 | Neurosci. Lett. | pmid:10081972 |