4-aminobutyric acid

4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.

Cross Reference

Introduction

To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-aminobutyric acid?

4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid

MeSH term MeSH ID Detail
Creutzfeldt-Jakob Syndrome D007562 7 associated lipids
Liver Cirrhosis, Alcoholic D008104 17 associated lipids
Hypocalcemia D006996 12 associated lipids
Brain Ischemia D002545 89 associated lipids
Ischemia D007511 18 associated lipids
Epilepsy D004827 35 associated lipids
Seizures D012640 87 associated lipids
Nerve Degeneration D009410 53 associated lipids
Hyperthyroidism D006980 12 associated lipids
Hypertension D006973 115 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Cerebrovascular Disorders D002561 25 associated lipids
Movement Disorders D009069 3 associated lipids
Protein-Energy Malnutrition D011502 9 associated lipids
Cushing Syndrome D003480 5 associated lipids
Granuloma, Foreign-Body D015745 5 associated lipids
Hyperalgesia D006930 42 associated lipids
Spinal Cord Injuries D013119 34 associated lipids
Brain Damage, Chronic D001925 6 associated lipids
Epilepsies, Partial D004828 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 4-aminobutyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 4-aminobutyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 4-aminobutyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-aminobutyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-aminobutyric acid

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Authors Title Published Journal PubMed Link
Xie M et al. Gastroprotective effect of gamma-aminobutyric acid against ethanol-induced gastric mucosal injury. 2017 Chem. Biol. Interact. pmid:28456544
Malongane F et al. The synergistic potential of various teas, herbs and therapeutic drugs in health improvement: a review. 2017 J. Sci. Food Agric. pmid:28585285
Daghestani MH et al. The role of apitoxin in alleviating propionic acid-induced neurobehavioral impairments in rat pups: The expression pattern of Reelin gene. 2017 Biomed. Pharmacother. pmid:28622594
Khongrum J and Wattanathorn J Laser Acupuncture at HT7 Improves the Cerebellar Disorders in Valproic Acid-Rat Model of Autism. 2017 J Acupunct Meridian Stud pmid:28889839
Lee NK and Paik HD Bioconversion Using Lactic Acid Bacteria: Ginsenosides, GABA, and Phenolic Compounds. 2017 J. Microbiol. Biotechnol. pmid:28297748
Androsova G et al. Comparative effectiveness of antiepileptic drugs in patients with mesial temporal lobe epilepsy with hippocampal sclerosis. 2017 Epilepsia pmid:28857179
Moradi-Afrapoli F et al. HPLC-Based Activity Profiling for GABAA Receptor Modulators in Searsia pyroides Using a Larval Zebrafish Locomotor Assay. 2017 Planta Med. pmid:28511229
Nevitt SJ et al. Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data. 2017 Cochrane Database Syst Rev pmid:28661008
Lin M et al. Ergosteryl 2-naphthoate, An Ergosterol Derivative, Exhibits Antidepressant Effects Mediated by the Modification of GABAergic and Glutamatergic Systems. 2017 Molecules pmid:28362353
Cantaut-Belarif Y et al. Microglia control the glycinergic but not the GABAergic synapses via prostaglandin E2 in the spinal cord. 2017 J. Cell Biol. pmid:28716844