4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Guptill JT et al. | Patient demographics and health plan paid costs in chronic inflammatory demyelinating polyneuropathy. | 2014 | Muscle Nerve | pmid:24639235 |
Tyzio R et al. | Oxytocin-mediated GABA inhibition during delivery attenuates autism pathogenesis in rodent offspring. | 2014 | Science | pmid:24503856 |
Park SA et al. | Kinetic characterization and molecular modeling of NAD(P)(+)-dependent succinic semialdehyde dehydrogenase from Bacillus subtilis as an ortholog YneI. | 2014 | J. Microbiol. Biotechnol. | pmid:24809290 |
Tarhonskaya H et al. | Non-enzymatic chemistry enables 2-hydroxyglutarate-mediated activation of 2-oxoglutarate oxygenases. | 2014 | Nat Commun | pmid:24594748 |
West S and Kenedi C | Strategies to prevent the neuropsychiatric side-effects of corticosteroids: a case report and review of the literature. | 2014 | Curr Opin Organ Transplant | pmid:24553497 |
Liu ZP et al. | Chronic stress impairs GABAergic control of amygdala through suppressing the tonic GABAA receptor currents. | 2014 | Mol Brain | pmid:24758222 |
Mennerick S et al. | Phosphatidylinositol 4,5-bisphosphate depletion fails to affect neurosteroid modulation of GABAA receptor function. | 2014 | Psychopharmacology (Berl.) | pmid:24553581 |
Pava MJ et al. | Endocannabinoid modulation of cortical up-states and NREM sleep. | 2014 | PLoS ONE | pmid:24520411 |
Kumamaru E et al. | Valproic acid selectively suppresses the formation of inhibitory synapses in cultured cortical neurons. | 2014 | Neurosci. Lett. | pmid:24708928 |
Marahatta A et al. | Soybean greatly reduces valproic acid plasma concentrations: a food-drug interaction study. | 2014 | Sci Rep | pmid:24618639 |