4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Norekian TP | GABAergic excitatory synapses and electrical coupling sustain prolonged discharges in the prey capture neural network of Clione limacina. | 1999 | J. Neurosci. | pmid:10024370 |
Pérez de la Mora M et al. | Effects of the vigilance promoting drug modafinil on the synthesis of GABA and glutamate in slices of rat hypothalamus. | 1999 | Neurosci. Lett. | pmid:10025588 |
Shen J et al. | In vivo chemical shift imaging of gamma-aminobutyric acid in the human brain. | 1999 | Magn Reson Med | pmid:10025609 |
Dewey SL et al. | A pharmacologic strategy for the treatment of nicotine addiction. | 1999 | Synapse | pmid:10025686 |
Mathern GW et al. | Hippocampal GABA and glutamate transporter immunoreactivity in patients with temporal lobe epilepsy. | 1999 | Neurology | pmid:10025773 |
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Jovanović K et al. | Localization and modulation of rhythmogenic locomotor network in the mudpuppy (Necturus maculatus). | 1998 | Ann. N. Y. Acad. Sci. | pmid:10026083 |
Pilch DS et al. | The thermodynamics of polyamide-DNA recognition: hairpin polyamide binding in the minor groove of duplex DNA. | 1999 | Biochemistry | pmid:10026298 |