4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Serrao M et al. | A case of myokymia-cramp syndrome successfully treated with gabapentin. | 1998 | Acta Neurol. Scand. | pmid:9875627 |
Commons KG et al. | In the ventromedial nucleus of the rat hypothalamus, GABA-immunolabeled neurons are abundant and are innervated by both enkephalin- and GABA-immunolabeled axon terminals. | 1999 | Brain Res. | pmid:9878688 |
Ikarashi Y et al. | Modulation of acetylcholine release via GABAA and GABAB receptors in rat striatum. | 1999 | Brain Res. | pmid:9878759 |
Yan XX and Ribak CE | Alteration of GABA transporter expression in the rat cerebral cortex following needle puncture and colchicine injection. | 1999 | Brain Res. | pmid:9878808 |
Feely M | Fortnightly review: drug treatment of epilepsy. | 1999 | BMJ | pmid:9880286 |
Glitsch M and Marty A | Presynaptic effects of NMDA in cerebellar Purkinje cells and interneurons. | 1999 | J. Neurosci. | pmid:9880571 |
Jin Y et al. | The Caenorhabditis elegans gene unc-25 encodes glutamic acid decarboxylase and is required for synaptic transmission but not synaptic development. | 1999 | J. Neurosci. | pmid:9880574 |
Perrais D and Ropert N | Effect of zolpidem on miniature IPSCs and occupancy of postsynaptic GABAA receptors in central synapses. | 1999 | J. Neurosci. | pmid:9880578 |
Collins DR and Paré D | Reciprocal changes in the firing probability of lateral and central medial amygdala neurons. | 1999 | J. Neurosci. | pmid:9880603 |
Green AR et al. | Elevation of brain GABA concentrations with amino-oxyacetic acid; effect on the hyperactivity syndrome produced by increased 5-hydroxytryptamine synthesis in rats. | 1976 | J. Neural Transm. | pmid:988113 |