4-aminobutyric acid

4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.

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Introduction

To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-aminobutyric acid?

4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid

MeSH term MeSH ID Detail
Migraine Disorders D008881 11 associated lipids
Mitral Valve Prolapse D008945 1 associated lipids
Morphine Dependence D009021 9 associated lipids
Motion Sickness D009041 1 associated lipids
Movement Disorders D009069 3 associated lipids
Multiple Sclerosis D009103 13 associated lipids
Muscle Cramp D009120 3 associated lipids
Muscle Hypertonia D009122 1 associated lipids
Muscle Rigidity D009127 4 associated lipids
Muscle Spasticity D009128 5 associated lipids
Muscular Diseases D009135 7 associated lipids
Myoclonus D009207 3 associated lipids
Myofascial Pain Syndromes D009209 1 associated lipids
Opioid-Related Disorders D009293 5 associated lipids
Nelson Syndrome D009347 1 associated lipids
Nerve Degeneration D009410 53 associated lipids
Nervous System Malformations D009421 1 associated lipids
Nervous System Diseases D009422 37 associated lipids
Neuralgia D009437 28 associated lipids
Neuritis D009443 4 associated lipids
Newcastle Disease D009521 4 associated lipids
Obesity D009765 29 associated lipids
Occupational Diseases D009784 42 associated lipids
Olivopontocerebellar Atrophies D009849 2 associated lipids
Pain D010146 64 associated lipids
Pain, Intractable D010148 4 associated lipids
Pain, Postoperative D010149 13 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Bulbar Palsy, Progressive D010244 1 associated lipids
Parkinson Disease D010300 53 associated lipids
Parkinson Disease, Secondary D010302 17 associated lipids
Perceptual Disorders D010468 3 associated lipids
Peripheral Nervous System Diseases D010523 33 associated lipids
Phantom Limb D010591 1 associated lipids
Pituitary Diseases D010900 2 associated lipids
Polyneuropathies D011115 3 associated lipids
Polyradiculopathy D011128 1 associated lipids
Prader-Willi Syndrome D011218 2 associated lipids
Presbycusis D011304 1 associated lipids
Protein-Energy Malnutrition D011502 9 associated lipids
Psychomotor Agitation D011595 3 associated lipids
Psychoses, Alcoholic D011604 2 associated lipids
Psychoses, Substance-Induced D011605 7 associated lipids
Puerperal Disorders D011644 4 associated lipids
Rabies D011818 4 associated lipids
Reflex Sympathetic Dystrophy D012019 4 associated lipids
Respiration Disorders D012120 5 associated lipids
Respiratory Paralysis D012133 1 associated lipids
Restless Legs Syndrome D012148 2 associated lipids
Retinal Detachment D012163 10 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 4-aminobutyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 4-aminobutyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 4-aminobutyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-aminobutyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-aminobutyric acid

Download all related citations
Per page 10 20 50 100 | Total 40318
Authors Title Published Journal PubMed Link
Luca G et al. Central and peripheral metabolic changes induced by gamma-hydroxybutyrate. 2015 Sleep pmid:25515097
Tao W et al. Brainstem brain-derived neurotrophic factor signaling is required for histone deacetylase inhibitor-induced pain relief. 2015 Mol. Pharmacol. pmid:25852071
Cui SQ et al. Puerarin protects against damage to spatial learning and memory ability in mice with chronic alcohol poisoning. 2015 Braz. J. Med. Biol. Res. pmid:25831201
Kardamakis AA et al. Tectal microcircuit generating visual selection commands on gaze-controlling neurons. 2015 Proc. Natl. Acad. Sci. U.S.A. pmid:25825743
Alatorre A et al. The local application of a flavonoid, (-)-epicatechin, increases the spiking of globus pallidus neurons in a dose-dependent manner and diminishes the catalepsy induced by haloperidol. 2015 Behav Pharmacol pmid:25503260
Yan X et al. Activation of toll like receptor 4 attenuates GABA synthesis and postsynaptic GABA receptor activities in the spinal dorsal horn via releasing interleukin-1 beta. 2015 J Neuroinflammation pmid:25571780
Brown AR et al. Developmentally regulated neurosteroid synthesis enhances GABAergic neurotransmission in mouse thalamocortical neurones. 2015 J. Physiol. (Lond.) pmid:25556800
Sabaliauskas N et al. Neurosteroid effects at α4βδ GABAA receptors alter spatial learning and synaptic plasticity in CA1 hippocampus across the estrous cycle of the mouse. 2015 Brain Res. pmid:25542386
Chen B et al. Cosmetic side effects of antiepileptic drugs in adults with epilepsy. 2015 Epilepsy Behav pmid:25513768
Zhang Y et al. Decreased carbon shunting from glucose toward oxidative metabolism in diet-induced ketotic rat brain. 2015 J. Neurochem. pmid:25314677