4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Curtis DR et al. | Central actions of benzodiazepines. | 1976 | Brain Res. | pmid:1000299 |
Maitre M et al. | In vitro studies into the effect of inhibition of rat brain succinic semialdehyde dehydrogenase on GABA synthesis and degradation. | 1976 | FEBS Lett. | pmid:1001470 |
Kovalev GV et al. | [Analysis of the ganglionic action of gamma-aminobutyric acid and its derivatives]. | 1976 Jul-Aug | Fiziol Zh | pmid:1001539 |
Mitchell JF | Release of physiologically active amino acids from intact brain and spinal-cord preparations. | 1976 | Biochem. Soc. Trans. | pmid:1001605 |
Fisher SK and Davies WE | 4-Aminobutyric acid in the mammalian cochlear nucleus. | 1976 | Biochem. Soc. Trans. | pmid:1001676 |
Wenk M et al. | Partial separation of synaptosomes accumulating 4-aminobutyrate or glutamate by zonal centrifugation on a discontinuous sucrose gradient. | 1976 | Hoppe-Seyler's Z. Physiol. Chem. | pmid:1002126 |
Guirado S et al. | Nucleus accumbens in the lizard Psammodromus algirus: chemoarchitecture and cortical afferent connections. | 1999 | J. Comp. Neurol. | pmid:10022193 |
Tobet SA et al. | Special relationship of gamma-aminobutyric acid to the ventromedial nucleus of the hypothalamus during embryonic development. | 1999 | J. Comp. Neurol. | pmid:10022198 |
Kushnir MM et al. | Analysis of gabapentin in serum and plasma by solid-phase extraction and gas chromatography-mass spectrometry for therapeutic drug monitoring. | 1999 Jan-Feb | J Anal Toxicol | pmid:10022201 |