4-aminobutyric acid

4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.

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Introduction

To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-aminobutyric acid?

4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid

MeSH term MeSH ID Detail
Insulinoma D007340 28 associated lipids
Insulin Resistance D007333 99 associated lipids
Inflammation D007249 119 associated lipids
Illusions D007088 1 associated lipids
Iatrogenic Disease D007049 1 associated lipids
Hypothyroidism D007037 32 associated lipids
Hypothermia D007035 19 associated lipids
Hypotension, Orthostatic D007024 3 associated lipids
Hypotension D007022 41 associated lipids
Hypophosphatasia D007014 1 associated lipids
Hypoparathyroidism D007011 2 associated lipids
Hypokalemia D007008 6 associated lipids
Hypocalcemia D006996 12 associated lipids
Hypertrophy D006984 16 associated lipids
Hyperthyroidism D006980 12 associated lipids
Hypertension, Portal D006975 12 associated lipids
Hypertension D006973 115 associated lipids
Hyperplasia D006965 34 associated lipids
Hyperphagia D006963 3 associated lipids
Hypernatremia D006955 1 associated lipids
Hyperlipidemias D006949 73 associated lipids
Hyperkinesis D006948 11 associated lipids
Hyperglycemic Hyperosmolar Nonketotic Coma D006944 4 associated lipids
Hyperglycemia D006943 21 associated lipids
Hyperemia D006940 25 associated lipids
Hyperalgesia D006930 42 associated lipids
Huntington Disease D006816 4 associated lipids
High Pressure Neurological Syndrome D006610 1 associated lipids
Hiccup D006606 1 associated lipids
Herpes Simplex D006561 3 associated lipids
Hepatitis A D006506 8 associated lipids
Hepatic Encephalopathy D006501 9 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Hemolysis D006461 131 associated lipids
Heart Arrest D006323 13 associated lipids
Hamartoma D006222 2 associated lipids
Pantothenate Kinase-Associated Neurodegeneration D006211 1 associated lipids
Glioma D005910 112 associated lipids
Tourette Syndrome D005879 3 associated lipids
Gigantism D005877 1 associated lipids
Filariasis D005368 6 associated lipids
Fever D005334 35 associated lipids
Fetal Resorption D005327 15 associated lipids
Fetal Growth Retardation D005317 9 associated lipids
Fetal Diseases D005315 8 associated lipids
Fetal Hypoxia D005311 3 associated lipids
Exanthema D005076 11 associated lipids
Esotropia D004948 1 associated lipids
Esophageal and Gastric Varices D004932 2 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 4-aminobutyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 4-aminobutyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 4-aminobutyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-aminobutyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-aminobutyric acid

Download all related citations
Per page 10 20 50 100 | Total 40318
Authors Title Published Journal PubMed Link
Ashby CR et al. Implication of the GABA(B) receptor in gamma vinyl-GABA's inhibition of cocaine-induced increases in nucleus accumbens dopamine. 1999 Synapse pmid:10024012
Pouzat C and Marty A Somatic recording of GABAergic autoreceptor current in cerebellar stellate and basket cells. 1999 J. Neurosci. pmid:10024354
Norekian TP GABAergic excitatory synapses and electrical coupling sustain prolonged discharges in the prey capture neural network of Clione limacina. 1999 J. Neurosci. pmid:10024370
Pérez de la Mora M et al. Effects of the vigilance promoting drug modafinil on the synthesis of GABA and glutamate in slices of rat hypothalamus. 1999 Neurosci. Lett. pmid:10025588
Shen J et al. In vivo chemical shift imaging of gamma-aminobutyric acid in the human brain. 1999 Magn Reson Med pmid:10025609
Dewey SL et al. A pharmacologic strategy for the treatment of nicotine addiction. 1999 Synapse pmid:10025686
Mathern GW et al. Hippocampal GABA and glutamate transporter immunoreactivity in patients with temporal lobe epilepsy. 1999 Neurology pmid:10025773
Petroff OA et al. Topiramate increases brain GABA, homocarnosine, and pyrrolidinone in patients with epilepsy. 1999 Neurology pmid:10025774
Jovanović K et al. Localization and modulation of rhythmogenic locomotor network in the mudpuppy (Necturus maculatus). 1998 Ann. N. Y. Acad. Sci. pmid:10026083
Pilch DS et al. The thermodynamics of polyamide-DNA recognition: hairpin polyamide binding in the minor groove of duplex DNA. 1999 Biochemistry pmid:10026298