4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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Pombal MA et al. | Cholinergic and GABAergic neuronal elements in the pineal organ of lampreys, and tract-tracing observations of differential connections of pinealofugal neurons. | 1999 | Cell Tissue Res. | pmid:9931367 |
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Hyde JC and Robinson N | Electron cytochemical localization of gamma-aminobutyric acid catabolism in rat cerebellar cortex. | 1976 | Histochemistry | pmid:993062 |
Gullis RJ and Rowe CE | The stimulation by synaptic transmitters of the incorporation of oleate into the phospholipid of synaptic membranes. | 1975 | Biochem. J. | pmid:993 |
Grabauskas G and Bradley RM | Ionic mechanism of GABAA biphasic synaptic potentials in gustatory nucleus of the solitary tract. | 1998 | Ann. N. Y. Acad. Sci. | pmid:9929643 |
Christensen TA et al. | GABAergic mechanisms that shape the temporal response to odors in moth olfactory projection neurons. | 1998 | Ann. N. Y. Acad. Sci. | pmid:9929641 |
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Eaton MJ et al. | Changes in GAD- and GABA- immunoreactivity in the spinal dorsal horn after peripheral nerve injury and promotion of recovery by lumbar transplant of immortalized serotonergic precursors. | 1998 | J. Chem. Neuroanat. | pmid:9924973 |
Dean C et al. | Dose-Response Study of Vigabatrin as add-on therapy in patients with uncontrolled complex partial seizures. | 1999 | Epilepsia | pmid:9924905 |