4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Nagamatsu S et al. | alpha-soluble N-ethylmaleimide-sensitive factor attachment protein is expressed in pancreatic beta cells and functions in insulin but not gamma-aminobutyric acid secretion. | 1999 | J. Biol. Chem. | pmid:10075705 |
Jung CS et al. | The GABA(C) receptor is present in cone-horizontal cell axon terminals isolated from catfish retina. | 1999 | Neurosci. Lett. | pmid:10076898 |
Jarry H et al. | Effects of age on GABA turnover rates in specific hypothalamic areas in female rats. | 1999 | Exp. Clin. Endocrinol. Diabetes | pmid:10077357 |
Pesold C et al. | Cortical bitufted, horizontal, and Martinotti cells preferentially express and secrete reelin into perineuronal nets, nonsynaptically modulating gene expression. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10077664 |
Christian M and Gillies G | Developing hypothalamic dopaminergic neurones as potential targets for environmental estrogens. | 1999 | J. Endocrinol. | pmid:10077742 |
Zhang H et al. | Effects of GABA-mediated inhibition on direction-dependent frequency tuning in the frog inferior colliculus. | 1999 | J. Comp. Physiol. A | pmid:10077865 |
Cestari IN et al. | GABA(A) receptor alpha4 subunit in DBA/2J and C57BL/6J mice. | 1998 | Brain Res. Bull. | pmid:10078620 |
Sasaki K et al. | Effects of bilobalide on gamma-aminobutyric acid levels and glutamic acid decarboxylase in mouse brain. | 1999 | Eur. J. Pharmacol. | pmid:10078989 |
Ong J et al. | Evaluation of 3-aminopropanesulphonamide analogues of GABA as antagonists at GABA(B) receptors in peripheral and central preparations. | 1999 | Eur. J. Pharmacol. | pmid:10078994 |
Menke JJ and Heins JR | Treatment of postherpetic neuralgia. | 1999 Mar-Apr | J Am Pharm Assoc (Wash) | pmid:10079653 |