4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Xu Z et al. | From the Cover: Functional Analysis Reveals Glutamate and Gamma-Aminobutyric Acid-Gated Chloride Channels as Targets of Avermectins in the Carmine Spider Mite. | 2017 | Toxicol. Sci. | pmid:27742867 |
Turner DP et al. | Using a graphical risk tool to examine willingness to take migraine prophylactic medications. | 2016 | Pain | pmid:27820159 |
Smetana KS et al. | Antiepileptic dosing for critically ill adult patients receiving renal replacement therapy. | 2016 | J Crit Care | pmid:27546759 |
Åžavk E | Neurologic Itch Management. | 2016 | Curr. Probl. Dermatol. | pmid:27578080 |
Ikarashi Y and Mizoguchi K | Neuropharmacological efficacy of the traditional Japanese Kampo medicine yokukansan and its active ingredients. | 2016 | Pharmacol. Ther. | pmid:27373856 |
Lai EC et al. | Comparative persistence of antiepileptic drugs in patients with epilepsy: A STROBE-compliant retrospective cohort study. | 2016 | Medicine (Baltimore) | pmid:27583857 |
Motoyama K et al. | Cholesterol-Lowering Effect of Octaarginine-Appended β-Cyclodextrin in Npc1-Trap-CHO Cells. | 2016 | Biol. Pharm. Bull. | pmid:27601082 |
Wongsamitkul N et al. | Toward Understanding Functional Properties and Subunit Arrangement of α4β2δ γ-Aminobutyric Acid, Type A (GABAA) Receptors. | 2016 | J. Biol. Chem. | pmid:27382064 |
Deligiannidis KM et al. | Peripartum neuroactive steroid and γ-aminobutyric acid profiles in women at-risk for postpartum depression. | 2016 | Psychoneuroendocrinology | pmid:27209438 |
Olexová L et al. | Increased anxiety-like behaviour and altered GABAergic system in the amygdala and cerebellum of VPA rats - An animal model of autism. | 2016 | Neurosci. Lett. | pmid:27353514 |
Setoyama D et al. | Plasma Metabolites Predict Severity of Depression and Suicidal Ideation in Psychiatric Patients-A Multicenter Pilot Analysis. | 2016 | PLoS ONE | pmid:27984586 |
Donvito G et al. | Palmitoylethanolamide Reverses Paclitaxel-Induced Allodynia in Mice. | 2016 | J. Pharmacol. Exp. Ther. | pmid:27608657 |
Wang L et al. | Metabolic Responses of Poplar to Apripona germari (Hope) as Revealed by Metabolite Profiling. | 2016 | Int J Mol Sci | pmid:27331808 |
Aseervatham GS et al. | Expression pattern of NMDA receptors reveals antiepileptic potential of apigenin 8-C-glucoside and chlorogenic acid in pilocarpine induced epileptic mice. | 2016 | Biomed. Pharmacother. | pmid:27470339 |
Kantrowitz JT et al. | d-Cycloserine, an NMDA Glutamate Receptor Glycine Site Partial Agonist, Induces Acute Increases in Brain Glutamate Plus Glutamine and GABA Comparable to Ketamine. | 2016 | Am J Psychiatry | pmid:27903101 |
Piplani S et al. | Neuroinformatics analyses reveal GABAt and SSADH as major proteins involved in anticonvulsant activity of valproic acid. | 2016 | Biomed. Pharmacother. | pmid:27261619 |
Tessarin P et al. | Influence of canopy-applied chitosan on the composition of organic cv. Sangiovese and Cabernet Sauvignon berries and wines. | 2016 | Food Chem | pmid:27211677 |
Mettang T | Uremic Itch Management. | 2016 | Curr. Probl. Dermatol. | pmid:27578082 |
Vanya M et al. | [Preconceptional and perinatal challenges of pregnancy in women with epilepsy]. | 2016 | Orv Hetil | pmid:27039994 |
Dadsetan S et al. | Infliximab reduces peripheral inflammation, neuroinflammation, and extracellular GABA in the cerebellum and improves learning and motor coordination in rats with hepatic encephalopathy. | 2016 | J Neuroinflammation | pmid:27623772 |