4-aminobutyric acid

4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.

Cross Reference

Introduction

To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-aminobutyric acid?

4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid

MeSH term MeSH ID Detail
Epilepsy, Absence D004832 5 associated lipids
Decerebrate State D003655 7 associated lipids
Psychoses, Alcoholic D011604 2 associated lipids
Amnesia D000647 12 associated lipids
Amnesia, Retrograde D000648 2 associated lipids
Cocaine-Related Disorders D019970 3 associated lipids
Akathisia, Drug-Induced D017109 2 associated lipids
Psychoses, Substance-Induced D011605 7 associated lipids
Hyperphagia D006963 3 associated lipids
Hyperglycemic Hyperosmolar Nonketotic Coma D006944 4 associated lipids
Muscle Rigidity D009127 4 associated lipids
Epilepsy, Temporal Lobe D004833 4 associated lipids
Retinoblastoma D012175 12 associated lipids
Epilepsy, Reflex D020195 5 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Spasms, Infantile D013036 3 associated lipids
Sleep Deprivation D012892 5 associated lipids
Psychomotor Agitation D011595 3 associated lipids
Dystonia D004421 3 associated lipids
Hypokinesia D018476 2 associated lipids
Urinary Bladder, Neurogenic D001750 3 associated lipids
Alcohol Amnestic Disorder D000425 2 associated lipids
Wernicke Encephalopathy D014899 2 associated lipids
Carcinoma, Embryonal D018236 8 associated lipids
Hyperammonemia D022124 5 associated lipids
Diabetes Insipidus D003919 5 associated lipids
Tinnitus D014012 4 associated lipids
Supranuclear Palsy, Progressive D013494 5 associated lipids
Asthenia D001247 5 associated lipids
Tuberculosis, Meningeal D014390 3 associated lipids
Self Mutilation D012652 2 associated lipids
Catatonia D002389 2 associated lipids
Hypotension, Orthostatic D007024 3 associated lipids
Tourette Syndrome D005879 3 associated lipids
Muscle Cramp D009120 3 associated lipids
Athetosis D001264 1 associated lipids
Chorea D002819 1 associated lipids
Presbycusis D011304 1 associated lipids
High Pressure Neurological Syndrome D006610 1 associated lipids
Motion Sickness D009041 1 associated lipids
Epilepsy, Post-Traumatic D004834 1 associated lipids
Stiff-Person Syndrome D016750 1 associated lipids
Esophageal and Gastric Varices D004932 2 associated lipids
Olivopontocerebellar Atrophies D009849 2 associated lipids
Skin Diseases, Vesiculobullous D012872 5 associated lipids
Nelson Syndrome D009347 1 associated lipids
Dystonia Musculorum Deformans D004422 1 associated lipids
Scrapie D012608 7 associated lipids
Bulbar Palsy, Progressive D010244 1 associated lipids
Epilepsy, Tonic-Clonic D004830 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 4-aminobutyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 4-aminobutyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 4-aminobutyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-aminobutyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-aminobutyric acid

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Authors Title Published Journal PubMed Link
Xu Z et al. From the Cover: Functional Analysis Reveals Glutamate and Gamma-Aminobutyric Acid-Gated Chloride Channels as Targets of Avermectins in the Carmine Spider Mite. 2017 Toxicol. Sci. pmid:27742867
Turner DP et al. Using a graphical risk tool to examine willingness to take migraine prophylactic medications. 2016 Pain pmid:27820159
Smetana KS et al. Antiepileptic dosing for critically ill adult patients receiving renal replacement therapy. 2016 J Crit Care pmid:27546759
Lai EC et al. Comparative persistence of antiepileptic drugs in patients with epilepsy: A STROBE-compliant retrospective cohort study. 2016 Medicine (Baltimore) pmid:27583857
Motoyama K et al. Cholesterol-Lowering Effect of Octaarginine-Appended β-Cyclodextrin in Npc1-Trap-CHO Cells. 2016 Biol. Pharm. Bull. pmid:27601082
Setoyama D et al. Plasma Metabolites Predict Severity of Depression and Suicidal Ideation in Psychiatric Patients-A Multicenter Pilot Analysis. 2016 PLoS ONE pmid:27984586
Donvito G et al. Palmitoylethanolamide Reverses Paclitaxel-Induced Allodynia in Mice. 2016 J. Pharmacol. Exp. Ther. pmid:27608657
Kantrowitz JT et al. d-Cycloserine, an NMDA Glutamate Receptor Glycine Site Partial Agonist, Induces Acute Increases in Brain Glutamate Plus Glutamine and GABA Comparable to Ketamine. 2016 Am J Psychiatry pmid:27903101
Mettang T Uremic Itch Management. 2016 Curr. Probl. Dermatol. pmid:27578082
Dadsetan S et al. Infliximab reduces peripheral inflammation, neuroinflammation, and extracellular GABA in the cerebellum and improves learning and motor coordination in rats with hepatic encephalopathy. 2016 J Neuroinflammation pmid:27623772