4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Omoto JJ et al. | Functional consequences of sulfhydryl modification of the γ-aminobutyric acid transporter 1 at a single solvent-exposed cysteine residue. | 2012 | J. Membr. Biol. | pmid:22918627 |
Osaka T | Thermoregulatory responses elicited by microinjection of L-glutamate and its interaction with thermogenic effects of GABA and prostaglandin E2 in the preoptic area. | 2012 | Neuroscience | pmid:22986159 |
Huo S et al. | Cultivation of Chlorella zofingiensis in bench-scale outdoor ponds by regulation of pH using dairy wastewater in winter, South China. | 2012 | Bioresour. Technol. | pmid:22858469 |
Bellance N et al. | Oncosecretomics coupled to bioenergetics identifies α-amino adipic acid, isoleucine and GABA as potential biomarkers of cancer: Differential expression of c-Myc, Oct1 and KLF4 coordinates metabolic changes. | 2012 | Biochim. Biophys. Acta | pmid:22842522 |
Shameem M and Patel AB | Glutamatergic and GABAergic metabolism in mouse brain under chronic nicotine exposure: implications for addiction. | 2012 | PLoS ONE | pmid:22848621 |
Al-Wadei HA et al. | Celecoxib and GABA cooperatively prevent the progression of pancreatic cancer in vitro and in xenograft models of stress-free and stress-exposed mice. | 2012 | PLoS ONE | pmid:22916251 |
Sumracki NM et al. | The effects of pregabalin and the glial attenuator minocycline on the response to intradermal capsaicin in patients with unilateral sciatica. | 2012 | PLoS ONE | pmid:22685578 |
Kilic FS et al. | Antinociceptive effects of gabapentin & its mechanism of action in experimental animal studies. | 2012 | Indian J. Med. Res. | pmid:22771591 |
Toyokura K et al. | Adaxial-abaxial patterning: a novel function of the GABA shunt. | 2012 | Plant Signal Behav | pmid:22751326 |