4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Vasil'ev VIu et al. | [Interaction of 4-aminobutyrate-transaminase from swine kidneys with 5'- and 6'-methyl derivatives of pyridoxal-5'-phosphate]. | 1976 | Biokhimiia | pmid:999979 |
Faletti AG et al. | beta-Endorphin blocks luteinizing hormone-releasing hormone release by inhibiting the nitricoxidergic pathway controlling its release. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9990091 |
Bravin M et al. | Control of spine formation by electrical activity in the adult rat cerebellum. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9990088 |
Kash SF et al. | Increased anxiety and altered responses to anxiolytics in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9990087 |
Maguire G | Rapid desensitization converts prolonged glutamate release into a transient EPSC at ribbon synapses between retinal bipolar and amacrine cells. | 1999 | Eur. J. Neurosci. | pmid:9987038 |
Lu YF et al. | Enhanced synaptic transmission and reduced threshold for LTP induction in fyn-transgenic mice. | 1999 | Eur. J. Neurosci. | pmid:9987012 |
Enz R and Cutting GR | GABAC receptor rho subunits are heterogeneously expressed in the human CNS and form homo- and heterooligomers with distinct physical properties. | 1999 | Eur. J. Neurosci. | pmid:9987010 |
Nitsch C | Antivitamin B6 induced ultrastructural changes in the hippocampus of the convulsant rabbit and its biochemical correlates. | 1976 | Acta Neurochir (Wien) | pmid:998335 |
Kim SS et al. | Focal lesion in the splenium of the corpus callosum in epileptic patients: antiepileptic drug toxicity? | 1999 | AJNR Am J Neuroradiol | pmid:9974067 |
Ayala-Grosso CA and Urbina-Paez R | Septohippocampal adaptive GABAergic responses by AF64A treatment. | 1999 | J. Neurosci. Res. | pmid:9972820 |