4-aminobutyric acid

4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.

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Introduction

To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-aminobutyric acid?

4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid

MeSH term MeSH ID Detail
Hepatic Encephalopathy D006501 9 associated lipids
Hypothyroidism D007037 32 associated lipids
Substance Withdrawal Syndrome D013375 9 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Pain, Postoperative D010149 13 associated lipids
Occupational Diseases D009784 42 associated lipids
Kidney Diseases D007674 29 associated lipids
Weight Gain D015430 101 associated lipids
Hyperemia D006940 25 associated lipids
Brain Diseases D001927 27 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 4-aminobutyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 4-aminobutyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 4-aminobutyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-aminobutyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-aminobutyric acid

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Authors Title Published Journal PubMed Link
Subramanian P et al. Temporal oscillations of phosphatases in N-phthaloyl gamma-aminobutyric acid treated rats. 1998 Indian J. Exp. Biol. pmid:10085783
Seidl JJ and Slawson JG Gabapentin for painful diabetic neuropathy. 1999 J Fam Pract pmid:10086757
Mozrzymas JW et al. Chlorpromazine inhibits miniature GABAergic currents by reducing the binding and by increasing the unbinding rate of GABAA receptors. 1999 J. Neurosci. pmid:10087062
Verheugen JA et al. Noninvasive measurements of the membrane potential and GABAergic action in hippocampal interneurons. 1999 J. Neurosci. pmid:10087068
Polgár E et al. GABAergic neurons that contain neuropeptide Y selectively target cells with the neurokinin 1 receptor in laminae III and IV of the rat spinal cord. 1999 J. Neurosci. pmid:10087077
Alkondon M et al. Choline and selective antagonists identify two subtypes of nicotinic acetylcholine receptors that modulate GABA release from CA1 interneurons in rat hippocampal slices. 1999 J. Neurosci. pmid:10087082
Brussaard AB et al. Changes in properties and neurosteroid regulation of GABAergic synapses in the supraoptic nucleus during the mammalian female reproductive cycle. 1999 J. Physiol. (Lond.) pmid:10087349
Ferraro L et al. The vigilance promoting drug modafinil increases extracellular glutamate levels in the medial preoptic area and the posterior hypothalamus of the conscious rat: prevention by local GABAA receptor blockade. 1999 Neuropsychopharmacology pmid:10088135
Rogers HJ and Lietman PS Inhibition by trimethoprim of some effects of epidermal growth factor on human fibroblasts in tissue culture. 1976 Biochem. Pharmacol. pmid:1008900
Möck M et al. GABAergic inhibition in the rat pontine nuclei is exclusively extrinsic: evidence from an in situ hybridization study for GAD67 mRNA. 1999 Exp Brain Res pmid:10090666