| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hepatic Encephalopathy | D006501 | 9 associated lipids |
| Hypothyroidism | D007037 | 32 associated lipids |
| Substance Withdrawal Syndrome | D013375 | 9 associated lipids |
| Leukemia, Erythroblastic, Acute | D004915 | 41 associated lipids |
| Pain, Postoperative | D010149 | 13 associated lipids |
| Occupational Diseases | D009784 | 42 associated lipids |
| Kidney Diseases | D007674 | 29 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Hyperemia | D006940 | 25 associated lipids |
| Brain Diseases | D001927 | 27 associated lipids |
4-aminobutyric acid
4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
Cross Reference
Introduction
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 4-aminobutyric acid?
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
PubChem Associated disorders and diseases
What pathways are associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 4-aminobutyric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 4-aminobutyric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 4-aminobutyric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| El Hage M et al. | Effects of valproate on glutamate metabolism in rat brain slices: a (13)C NMR study. | 2012 | Epilepsy Res. | pmid:22088480 |
| Meye FJ et al. | Morphine withdrawal enhances constitutive μ-opioid receptor activity in the ventral tegmental area. | 2012 | J. Neurosci. | pmid:23152596 |
| Geng Y et al. | Triptolide down-regulates COX-2 expression and PGE2 release by suppressing the activity of NF-κB and MAP kinases in lipopolysaccharide-treated PC12 cells. | 2012 | Phytother Res | pmid:21717513 |
| Miklós IH and Kovács KJ | Reorganization of synaptic inputs to the hypothalamic paraventricular nucleus during chronic psychogenic stress in rats. | 2012 | Biol. Psychiatry | pmid:22137593 |
| Hazell GG et al. | G protein-coupled receptors in the hypothalamic paraventricular and supraoptic nuclei--serpentine gateways to neuroendocrine homeostasis. | 2012 | Front Neuroendocrinol | pmid:21802439 |
| Perego C et al. | Neurosteroid allopregnanolone regulates EAAC1-mediated glutamate uptake and triggers actin changes in Schwann cells. | 2012 | J. Cell. Physiol. | pmid:21688266 |
| Lin PP et al. | Inhibition of cardiac hypertrophy by probiotic-fermented purple sweet potato yogurt in spontaneously hypertensive rat hearts. | 2012 | Int. J. Mol. Med. | pmid:23064753 |
| Hagerman R et al. | Fragile X syndrome and targeted treatment trials. | 2012 | Results Probl Cell Differ | pmid:22009360 |
| Bracamontes JR et al. | A neurosteroid potentiation site can be moved among GABAA receptor subunits. | 2012 | J. Physiol. (Lond.) | pmid:22988137 |
| Li WR et al. | Pharmacokinetics of natural borneol after oral administration in mice brain and its effect on excitation ratio. | 2012 | Eur J Drug Metab Pharmacokinet | pmid:21948240 |
| Wang M et al. | Acute restraint stress enhances hippocampal endocannabinoid function via glucocorticoid receptor activation. | 2012 | J. Psychopharmacol. (Oxford) | pmid:21890595 |
| Garrido P et al. | Aging impairs the control of prefrontal cortex on the release of corticosterone in response to stress and on memory consolidation. | 2012 | Neurobiol. Aging | pmid:21794953 |
| Yip PK and Malaspina A | Spinal cord trauma and the molecular point of no return. | 2012 | Mol Neurodegener | pmid:22315999 |
| Yang M et al. | NMR analysis of the rat neurochemical changes induced by middle cerebral artery occlusion. | 2012 | Talanta | pmid:22265479 |
| Ihara D et al. | Deltamethrin, a type II pyrethroid insecticide, has neurotrophic effects on neurons with continuous activation of the Bdnf promoter. | 2012 | Neuropharmacology | pmid:22079160 |
| Park H et al. | Expression, immobilization and enzymatic properties of glutamate decarboxylase fused to a cellulose-binding domain. | 2012 | Int J Mol Sci | pmid:22312257 |
| Nugent BM et al. | Kinases SPAK and OSR1 are upregulated by estradiol and activate NKCC1 in the developing hypothalamus. | 2012 | J. Neurosci. | pmid:22238094 |
| Wiersinga WJ et al. | Therapy-resistant opsoclonus-myoclonus syndrome secondary to HIV-1 infection. | 2012 | Clin. Infect. Dis. | pmid:22247305 |
| Bosch OG et al. | Reconsidering GHB: orphan drug or new model antidepressant? | 2012 | J. Psychopharmacol. (Oxford) | pmid:21926421 |
| Dahl SR et al. | Determination of γ-hydroxybutyrate (GHB), β-hydroxybutyrate (BHB), pregabalin, 1,4-butane-diol (1,4BD) and γ-butyrolactone (GBL) in whole blood and urine samples by UPLC-MSMS. | 2012 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:22226469 |
| Villarreal-Chiu JF et al. | The genes and enzymes of phosphonate metabolism by bacteria, and their distribution in the marine environment. | 2012 | Front Microbiol | pmid:22303297 |
| Chuang SM et al. | Zinc ion enhances GABA tea-mediated oxidative DNA damage. | 2012 | J. Agric. Food Chem. | pmid:22264004 |
| Nomoto M et al. | Dysfunction of the RAR/RXR signaling pathway in the forebrain impairs hippocampal memory and synaptic plasticity. | 2012 | Mol Brain | pmid:22316320 |
| Huang J et al. | Solid-state NMR analyses reveal the structure dependence of the molecular dynamics for ω-amino acids. | 2012 | J Phys Chem B | pmid:22251439 |
| Lucenteforte E et al. | Complementary and Alternative Drugs Use among Preoperative Patients: A Cross-Sectional Study in Italy. | 2012 | Evid Based Complement Alternat Med | pmid:21822441 |
| Mura E et al. | Dual effect of beta-amyloid on α7 and α4β2 nicotinic receptors controlling the release of glutamate, aspartate and GABA in rat hippocampus. | 2012 | PLoS ONE | pmid:22253754 |
| Beck C et al. | The diversity of cyanobacterial metabolism: genome analysis of multiple phototrophic microorganisms. | 2012 | BMC Genomics | pmid:22300633 |
| Jones JD et al. | Unusual case of a swollen painful toe in a young man. | 2012 | Arthritis Care Res (Hoboken) | pmid:22278969 |
| Verduzco LA et al. | Subdural hematoma after an epidural blood patch. | 2012 | Int J Obstet Anesth | pmid:22317890 |
| Lecker I et al. | Tranexamic acid concentrations associated with human seizures inhibit glycine receptors. | 2012 | J. Clin. Invest. | pmid:23187124 |
| Lecrux C et al. | Pyramidal cells and cytochrome P450 epoxygenase products in the neurovascular coupling response to basal forebrain cholinergic input. | 2012 | J. Cereb. Blood Flow Metab. | pmid:22293985 |
| Schuller HM et al. | Regulation of pancreatic cancer by neuropsychological stress responses: a novel target for intervention. | 2012 | Carcinogenesis | pmid:22072614 |
| Chen ZW et al. | Deep amino acid sequencing of native brain GABAA receptors using high-resolution mass spectrometry. | 2012 | Mol. Cell Proteomics | pmid:22338125 |
| Baldacci-Cresp F et al. | (Homo)glutathione deficiency impairs root-knot nematode development in Medicago truncatula. | 2012 | PLoS Pathog. | pmid:22241996 |
| Beate K et al. | Genetics of isolated hypogonadotropic hypogonadism: role of GnRH receptor and other genes. | 2012 | Int J Endocrinol | pmid:22229029 |
| Martisova E et al. | Long lasting effects of early-life stress on glutamatergic/GABAergic circuitry in the rat hippocampus. | 2012 | Neuropharmacology | pmid:22245561 |
| Al-Wadei HA et al. | Social stress promotes and γ-aminobutyric acid inhibits tumor growth in mouse models of non-small cell lung cancer. | 2012 | Cancer Prev Res (Phila) | pmid:21955519 |
| Nothdurfter C et al. | Recent developments in potential anxiolytic agents targeting GABAA/BzR complex or the translocator protein (18kDa) (TSPO). | 2012 | Curr Top Med Chem | pmid:22204486 |
| Babenko O et al. | Genomic and epigenomic responses to chronic stress involve miRNA-mediated programming. | 2012 | PLoS ONE | pmid:22291890 |
| Wang H et al. | Production and characterization of antifungal compounds produced by Lactobacillus plantarum IMAU10014. | 2012 | PLoS ONE | pmid:22276116 |
| Sadiq S et al. | Metal toxicity at the synapse: presynaptic, postsynaptic, and long-term effects. | 2012 | J Toxicol | pmid:22287959 |
| López-López J et al. | Inferior alveolar nerve injury resulting from overextension of an endodontic sealer: non-surgical management using the GABA analogue pregabalin. | 2012 | Int Endod J | pmid:21883296 |
| Benjaminsen E et al. | A man in his seventies with prolonged myasthenic crisis. | 2012 | Tidsskr. Nor. Laegeforen. | pmid:23076489 |
| Uetake K et al. | Calming effect of orally administered γ-aminobutyric acid in Shih Tzu dogs. | 2012 | Anim. Sci. J. | pmid:23216545 |
| Yalçın O | Genes and molecular mechanisms involved in the epileptogenesis of idiopathic absence epilepsies. | 2012 | Seizure | pmid:22206818 |
| Duszczyk-Budhathoki M et al. | Administration of thimerosal to infant rats increases overflow of glutamate and aspartate in the prefrontal cortex: protective role of dehydroepiandrosterone sulfate. | 2012 | Neurochem. Res. | pmid:22015977 |
| Wu TY et al. | Effect of antioxidant activity and functional properties of Chingshey purple sweet potato fermented milk by Lactobacillus acidophilus, L. delbrueckii subsp. lactis, and L. gasseri strains. | 2012 | J. Food Sci. | pmid:22182227 |
| Maschio M et al. | Effect of pregabalin add-on treatment on seizure control, quality of life, and anxiety in patients with brain tumour-related epilepsy: a pilot study. | 2012 | Epileptic Disord | pmid:23248037 |
| Rossi S et al. | Interleukin-1β causes anxiety by interacting with the endocannabinoid system. | 2012 | J. Neurosci. | pmid:23035099 |
| Merewitz EB et al. | Elevated cytokinin content in ipt transgenic creeping bentgrass promotes drought tolerance through regulating metabolite accumulation. | 2012 | J. Exp. Bot. | pmid:22131157 |