4-aminobutyric acid

4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.

Cross Reference

Introduction

To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-aminobutyric acid?

4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid

MeSH term MeSH ID Detail
Hepatic Encephalopathy D006501 9 associated lipids
Hypothyroidism D007037 32 associated lipids
Substance Withdrawal Syndrome D013375 9 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Pain, Postoperative D010149 13 associated lipids
Occupational Diseases D009784 42 associated lipids
Kidney Diseases D007674 29 associated lipids
Weight Gain D015430 101 associated lipids
Hyperemia D006940 25 associated lipids
Brain Diseases D001927 27 associated lipids
Per page 10 20 50 100 | Total 280

PubChem Associated disorders and diseases

What pathways are associated with 4-aminobutyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with 4-aminobutyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with 4-aminobutyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-aminobutyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-aminobutyric acid

Download all related citations
Per page 10 20 50 100 | Total 40318
Authors Title Published Journal PubMed Link
Prelle K et al. Endpoints of drug discovery for menopausal vasomotor symptoms: interpretation of data from a proxy of disease. 2012 Menopause pmid:22473248
Lee KY and Gold MS Inflammatory mediators potentiate high affinity GABA(A) currents in rat dorsal root ganglion neurons. 2012 Neurosci. Lett. pmid:22580064
Thompson AJ et al. The pharmacological profile of ELIC, a prokaryotic GABA-gated receptor. 2012 Neuropharmacology pmid:22677470
Boughton BA et al. The crystal structure of dihydrodipicolinate synthase from Escherichia coli with bound pyruvate and succinic acid semialdehyde: unambiguous resolution of the stereochemistry of the condensation product. 2012 Proteins pmid:22552955
Omoto JJ et al. Functional consequences of sulfhydryl modification of the γ-aminobutyric acid transporter 1 at a single solvent-exposed cysteine residue. 2012 J. Membr. Biol. pmid:22918627
Osaka T Thermoregulatory responses elicited by microinjection of L-glutamate and its interaction with thermogenic effects of GABA and prostaglandin E2 in the preoptic area. 2012 Neuroscience pmid:22986159
Huo S et al. Cultivation of Chlorella zofingiensis in bench-scale outdoor ponds by regulation of pH using dairy wastewater in winter, South China. 2012 Bioresour. Technol. pmid:22858469
Ariyawardana A et al. Use of single- and multi-drug regimens in the management of classic (idiopathic) trigeminal neuralgia: an 11-year experience at a single Sri Lankan institution. 2012 J Investig Clin Dent pmid:22180190
Bellance N et al. Oncosecretomics coupled to bioenergetics identifies α-amino adipic acid, isoleucine and GABA as potential biomarkers of cancer: Differential expression of c-Myc, Oct1 and KLF4 coordinates metabolic changes. 2012 Biochim. Biophys. Acta pmid:22842522
Abbasi E et al. Neuroprotective effects of vitexin, a flavonoid, on pentylenetetrazole-induced seizure in rats. 2012 Chem Biol Drug Des pmid:22554436
Shameem M and Patel AB Glutamatergic and GABAergic metabolism in mouse brain under chronic nicotine exposure: implications for addiction. 2012 PLoS ONE pmid:22848621
Simpson SM et al. The antidepressant phenelzine enhances memory in the double Y-maze and increases GABA levels in the hippocampus and frontal cortex of rats. 2012 Pharmacol. Biochem. Behav. pmid:22503968
Al-Wadei HA et al. Celecoxib and GABA cooperatively prevent the progression of pancreatic cancer in vitro and in xenograft models of stress-free and stress-exposed mice. 2012 PLoS ONE pmid:22916251
Ito S et al. Etodolac, a cyclooxygenase-2 inhibitor, attenuates paclitaxel-induced peripheral neuropathy in a mouse model of mechanical allodynia. 2012 J. Pharmacol. Exp. Ther. pmid:22460833
Ogawa K et al. Pharmacological characterization of lysophosphatidic acid-induced pain with clinically relevant neuropathic pain drugs. 2012 Eur J Pain pmid:22337641
Sumracki NM et al. The effects of pregabalin and the glial attenuator minocycline on the response to intradermal capsaicin in patients with unilateral sciatica. 2012 PLoS ONE pmid:22685578
Kilic FS et al. Antinociceptive effects of gabapentin & its mechanism of action in experimental animal studies. 2012 Indian J. Med. Res. pmid:22771591
Toyokura K et al. Adaxial-abaxial patterning: a novel function of the GABA shunt. 2012 Plant Signal Behav pmid:22751326
Thompson AJ et al. Ginkgolide B and bilobalide block the pore of the 5-HT₃receptor at a location that overlaps the picrotoxin binding site. 2011 Feb-Mar Neuropharmacology pmid:21059362
Úriz M et al. Ursodeoxycholic acid is conjugated with taurine to promote secretin-stimulated biliary hydrocholeresis in the normal rat. 2011 PLoS ONE pmid:22194894
Siniscalco D et al. Role of neurotrophins in neuropathic pain. 2011 Curr Neuropharmacol pmid:22654713
Baier CJ et al. Disclosure of cholesterol recognition motifs in transmembrane domains of the human nicotinic acetylcholine receptor. 2011 Sci Rep pmid:22355588
Steidl S et al. Mâ‚… muscarinic receptors mediate striatal dopamine activation by ventral tegmental morphine and pedunculopontine stimulation in mice. 2011 PLoS ONE pmid:22102904
Shen Y et al. Biochemical properties and potential applications of recombinant leucine aminopeptidase from Bacillus kaustophilus CCRC 11223. 2011 Int J Mol Sci pmid:22174620
Louis ED Treatment of Essential Tremor: Are there Issues We are Overlooking? 2011 Front Neurol pmid:22275907
Li GY et al. Visible light may directly induce nuclear DNA damage triggering the death pathway in RGC-5 cells. 2011 Mol. Vis. pmid:22194654
Schröder J et al. Complete genome sequence of Corynebacterium variabile DSM 44702 isolated from the surface of smear-ripened cheeses and insights into cheese ripening and flavor generation. 2011 BMC Genomics pmid:22053731
Aryal UK et al. Dynamic proteomic profiling of a unicellular cyanobacterium Cyanothece ATCC51142 across light-dark diurnal cycles. 2011 BMC Syst Biol pmid:22133144
Wu H et al. NMR-based metabolomic investigations on the differential responses in adductor muscles from two pedigrees of Manila clam Ruditapes philippinarum to Cadmium and Zinc. 2011 Mar Drugs pmid:22131959
Fujimura K et al. Circular DNA intermediate in the duplication of Nile tilapia vasa genes. 2011 PLoS ONE pmid:22216289
Gal-Ben-Ari S and Rosenblum K Molecular mechanisms underlying memory consolidation of taste information in the cortex. 2011 Front Behav Neurosci pmid:22319481
Lorentz H et al. Contact lens physical properties and lipid deposition in a novel characterized artificial tear solution. 2011 Mol. Vis. pmid:22219635
Goyal N et al. Electroencephalographic abnormalities in clozapine-treated patients: a cross-sectional study. 2011 Psychiatry Investig pmid:22216049
Lee HL and Lee JK Lance-adams syndrome. 2011 Ann Rehabil Med pmid:22506225
El Hage M et al. Rat brain slices oxidize glucose at high rates: a (13)C NMR study. 2011 Neurochem. Int. pmid:22067134
Mitra S and Chopra P Chirality and anaesthetic drugs: A review and an update. 2011 Indian J Anaesth pmid:22223897
Mamidi P and Thakar AB Efficacy of Ashwagandha (Withania somnifera Dunal. Linn.) in the management of psychogenic erectile dysfunction. 2011 Ayu pmid:22529644
Wadman RI et al. Drug treatment for spinal muscular atrophy types II and III. 2011 Cochrane Database Syst Rev pmid:22161400
Shigetomi E et al. TRPA1 channels regulate astrocyte resting calcium and inhibitory synapse efficacy through GAT-3. 2011 Nat. Neurosci. pmid:22158513
Koen N and Stein DJ Pharmacotherapy of anxiety disorders: a critical review. 2011 Dialogues Clin Neurosci pmid:22275848
Barvaliya M et al. Phenytoin induced chorea in a pediatric patient: An interaction between phenytoin, phenobarbital and clobazam. 2011 Indian J Pharmacol pmid:22144787
Vallée N et al. Effect of an hyperbaric nitrogen narcotic ambience on arginine and citrulline levels, the precursor and co-product of nitric oxide, in rat striatum. 2011 Med Gas Res pmid:22146244
Buskova J et al. Gabapentin in the treatment of dementia-associated nocturnal agitation. 2011 Med. Sci. Monit. pmid:22129906
Apovian CM Management of diabetes across the course of disease: minimizing obesity-associated complications. 2011 Diabetes Metab Syndr Obes pmid:22135499
Porth I et al. Defense mechanisms against herbivory in Picea: sequence evolution and expression regulation of gene family members in the phenylpropanoid pathway. 2011 BMC Genomics pmid:22177423
Cesetti T et al. GABA Not Only a Neurotransmitter: Osmotic Regulation by GABA(A)R Signaling. 2011 Front Cell Neurosci pmid:22319472
Frye CA et al. Effects and Mechanisms of 3α,5α,-THP on Emotion, Motivation, and Reward Functions Involving Pregnane Xenobiotic Receptor. 2011 Front Neurosci pmid:22294977
Hulin MW et al. Neurosteroid Binding Sites on the GABA(A) Receptor Complex as Novel Targets for Therapeutics to Reduce Alcohol Abuse and Dependence. 2011 Adv Pharmacol Sci pmid:22110489
Gunn BG et al. Neurosteroids and GABA(A) Receptor Interactions: A Focus on Stress. 2011 Front Neurosci pmid:22164129
Ajdari Z et al. Assessment of monacolin in the fermented products using Monascus purpureus FTC5391. 2011 J. Biomed. Biotechnol. pmid:22190851