4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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pmid:10210670 | ||||
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Arndt CF et al. | Outer retinal dysfunction in patients treated with vigabatrin. | 1999 | Neurology | pmid:10214744 |
Papp EC et al. | Medial septal and median raphe innervation of vasoactive intestinal polypeptide-containing interneurons in the hippocampus. | 1999 | Neuroscience | pmid:10215142 |
Estevez AY et al. | Effects of anion channel blockers on hyposmotically induced amino acid release from the in vivo rat cerebral cortex. | 1999 | Neurochem. Res. | pmid:10215520 |
Rapallino MV et al. | Stimulation of chloride in-->out permeation across the Deiters' neuron membrane by pentobarbital on the cytoplasmic side: additional evidence of GABA(A) receptors acting as chloride extrusion pumps. | 1999 | Neurochem. Res. | pmid:10215521 |
Hu LA and King SC | Identification of the amine-polyamine-choline transporter superfamily 'consensus amphipathic region' as the target for inactivation of the Escherichia coli GABA transporter GabP by thiol modification reagents. Role of Cys-300 in restoring thiol sensitivity to Gabp lacking Cys. | 1999 | Biochem. J. | pmid:10215604 |
Xiong H et al. | Mutual regulation between the intercellular messengers nitric oxide and brain-derived neurotrophic factor in rodent neocortical neurons. | 1999 | Eur. J. Neurosci. | pmid:10215909 |
Ali AB et al. | IPSPs elicited in CA1 pyramidal cells by putative basket cells in slices of adult rat hippocampus. | 1999 | Eur. J. Neurosci. | pmid:10215927 |
Maruyama S and Kawasaki T | Further electrophysiological evidence for the GABA-like effect of droperidol in the Purkinje cells of the cat cerebellum. | 1976 | Jpn. J. Pharmacol. | pmid:1021614 |