4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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Misslin R et al. | Action of di-n-propylacetate on the spontaneous and acquired behaviour in goldfish, mice and rats. | 1976 | Pharmacol. Biochem. Behav. | pmid:981281 |
Kong X et al. | [Effects of zinc deficiency in fodder on brain development, learning and memory in rats]. | 1997 | Zhonghua Yu Fang Yi Xue Za Zhi | pmid:9812610 |
Myrick H et al. | Gabapentin treatment of alcohol withdrawal. | 1998 | Am J Psychiatry | pmid:9812141 |
Beneyto M et al. | Auditory connections and neurochemistry of the sagulum. | 1998 | J. Comp. Neurol. | pmid:9811112 |
Anadón R et al. | Distribution of GABA immunoreactivity in the central and peripheral nervous system of amphioxus (Branchiostoma lanceolatum Pallas). | 1998 | J. Comp. Neurol. | pmid:9811110 |
Southam E et al. | Lamotrigine inhibits monoamine uptake in vitro and modulates 5-hydroxytryptamine uptake in rats. | 1998 | Eur. J. Pharmacol. | pmid:9809864 |
Banerjee PK et al. | Absence seizures decrease steroid modulation of t-[35S]butylbicyclophosphorothionate binding in thalamic relay nuclei. | 1998 | J. Pharmacol. Exp. Ther. | pmid:9808708 |
Zhao TJ et al. | Decreased benzodiazepine binding with little effect on gamma-aminobutyric acid binding in rat brain after treatment with antisense oligodeoxynucleotide to the gamma-aminobutyric acidA receptor gamma-2 subunit. | 1998 | J. Pharmacol. Exp. Ther. | pmid:9808706 |
Lu Y et al. | Pharmacological characterization of nicotinic receptor-stimulated GABA release from mouse brain synaptosomes. | 1998 | J. Pharmacol. Exp. Ther. | pmid:9808692 |
Shen EH et al. | Seizure sensitivity and GABAergic modulation of ethanol sensitivity in selectively bred FAST and SLOW mouse lines. | 1998 | J. Pharmacol. Exp. Ther. | pmid:9808687 |
Dumka VK et al. | Central modulation of formalin-induced acute peripheral inflammation & pain by some putative amino acid neurotransmitters in rats. | 1998 | Indian J. Med. Res. | pmid:9805845 |
Vamvakides A | [D-cycloserine is active in the adult mouse and inactive in the aged mouse, in the forced swim test]. | 1998 | Ann Pharm Fr | pmid:9805820 |
pmid:9804795 | ||||
pmid:9804738 | ||||
pmid:9804371 | ||||
pmid:9804316 | ||||
pmid:9804302 | ||||
pmid:9803010 | ||||
pmid:9801393 | ||||
pmid:9801365 | ||||
pmid:9798839 | ||||
pmid:9797030 | ||||
Sánchez-Valiente S | [Treatment of neuropathic pain with gabapentin ++]. | 1998 | Rev Neurol | pmid:9796018 |
Alibardi L | Ultrastructural and immunocytochemical characterization of commissural neurons in the ventral cochlear nucleus of the rat. | 1998 | Ann. Anat. | pmid:9795693 |
Alibardi L | Ultrastructural and immunocytochemical characterization of neurons in the rat ventral cochlear nucleus projecting to the inferior colliculus. | 1998 | Ann. Anat. | pmid:9795692 |
New KC et al. | Novel synthesis and release of GABA in cerebellar granule cell cultures after infection with defective herpes simplex virus vectors expressing glutamic acid decarboxylase. | 1998 | Brain Res. Mol. Brain Res. | pmid:9795182 |
Higo A et al. | Removal of hydroxyl radical facilitates Ca2+-dependent [3H]GABA release by peroxynitrite. | 1998 | Brain Res. Mol. Brain Res. | pmid:9795162 |
Zhang Y and Liu GQ | Sodium and chloride-dependent high and low-affinity uptakes of GABA by brain capillary endothelial cells. | 1998 | Brain Res. | pmid:9795097 |
Acosta GB | Administration of cholecystokinin sulphated octapeptide (CCK-8S) induces changes on rat amino acid tissue levels and on a behavioral test for anxiety. | 1998 | Gen. Pharmacol. | pmid:9792229 |
GarcÃa SC et al. | Delta-aminolevulinic acid transport through blood-brain barrier. | 1998 | Gen. Pharmacol. | pmid:9792218 |
Drucker-ColÃn RR and Rojas-RamÃrez JA | New approaches to the study of the neurochemical basis of sleep and wakefulness. | 1976 | Adv Psychobiol | pmid:9792 |
Martin DS and Haywood JR | Reduced GABA inhibition of sympathetic function in renal-wrapped hypertensive rats. | 1998 | Am. J. Physiol. | pmid:9791069 |
Pepeu G and Blandina P | The acetylcholine, GABA, glutamate triangle in the rat forebrain. | 1998 Oct-Dec | J. Physiol. Paris | pmid:9789836 |
Albuquerque EX et al. | Contribution of nicotinic receptors to the function of synapses in the central nervous system: the action of choline as a selective agonist of alpha 7 receptors. | 1998 Jun-Aug | J. Physiol. Paris | pmid:9789829 |
Fisher JL et al. | Nicotine modifies the activity of ventral tegmental area dopaminergic neurons and hippocampal GABAergic neurons. | 1998 Jun-Aug | J. Physiol. Paris | pmid:9789810 |
Erfurth A et al. | An open label study of gabapentin in the treatment of acute mania. | 1998 Sep-Oct | J Psychiatr Res | pmid:9789203 |
Brauer K et al. | Electron microscopic evidence for a cholinergic innervation of GABAergic parvalbumin-immunoreactive neurons in the rat medial septum. | 1998 | J. Neurosci. Res. | pmid:9788283 |
Cassidy RM and Gale K | Mediodorsal thalamus plays a critical role in the development of limbic motor seizures. | 1998 | J. Neurosci. | pmid:9787005 |
Jones MV et al. | Defining affinity with the GABAA receptor. | 1998 | J. Neurosci. | pmid:9786967 |
Kouznetsova M and Nistri A | Modulation by substance P of synaptic transmission in the mouse hippocampal slice. | 1998 | Eur. J. Neurosci. | pmid:9786202 |
Ben-Ari Y et al. | Inhibitory effects of acetylcholine on neurones in the feline nucleus reticularis thalami. | 1976 | J. Physiol. (Lond.) | pmid:978591 |
Bedwani JR et al. | Some amino acids as myometrial spasmogens [proceedings]. | 1976 | J. Physiol. (Lond.) | pmid:978556 |
Saul'skaia NB and Gorbachevskaia AI | [Participation of the hippocampus in regulation of GABA release in the nucleus accumbens during emotional conditioning]. | 1998 May-Jun | Ross Fiziol Zh Im I M Sechenova | pmid:9785409 |
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