4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Rapinesi C et al. | Epilepsy and brain injury: a case report of a dramatic neuropsychiatric vicious circle. | 2013 | Brain Inj | pmid:23782232 |
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Lin JN et al. | Chemical constituents and anticancer activity of yellow camellias against MDA-MB-231 human breast cancer cells. | 2013 | J. Agric. Food Chem. | pmid:24001127 |
Reddy K et al. | SGE-102: a novel therapy for refractory status epilepticus. | 2013 | Epilepsia | pmid:24001082 |
Michelson JD et al. | Multimodal analgesia therapy reduces length of hospitalization in patients undergoing fusions of the ankle and hindfoot. | 2013 | Foot Ankle Int | pmid:23836812 |
Dionisio L et al. | GABAA receptor plasticity in Jurkat T cells. | 2013 | Biochimie | pmid:24012548 |
Derbenev AV and Smith BN | Dexamethasone rapidly increases GABA release in the dorsal motor nucleus of the vagus via retrograde messenger-mediated enhancement of TRPV1 activity. | 2013 | PLoS ONE | pmid:23936221 |
Baglo Y et al. | Homology modeling of human γ-butyric acid transporters and the binding of pro-drugs 5-aminolevulinic acid and methyl aminolevulinic acid used in photodynamic therapy. | 2013 | PLoS ONE | pmid:23762315 |
Shamsi Meymandi M and Keyhanfar F | Assessment of the antinociceptive effects of pregabalin alone or in combination with morphine during acetic acid-induced writhing in mice. | 2013 | Pharmacol. Biochem. Behav. | pmid:23921185 |
Jang HJ et al. | Layer- and cell-type-specific tonic GABAergic inhibition of pyramidal neurons in the rat visual cortex. | 2013 | Pflugers Arch. | pmid:23812164 |
Das UN | Autism as a disorder of deficiency of brain-derived neurotrophic factor and altered metabolism of polyunsaturated fatty acids. | 2013 | Nutrition | pmid:23911220 |
Jin Z et al. | Potentiating effect of glabridin on GABAA receptor-mediated responses in dorsal raphe neurons. | 2013 | Planta Med. | pmid:23975867 |
Guo H et al. | Influences of hydrocarbon linkers on the receptor binding affinities of gonadotropin-releasing hormone peptides. | 2013 | Bioorg. Med. Chem. Lett. | pmid:24018188 |