4-aminobutyric acid

4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.

Cross Reference

Introduction

To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-aminobutyric acid?

4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid

MeSH term MeSH ID Detail
Fetal Resorption D005327 15 associated lipids
Dyskinesia, Drug-Induced D004409 15 associated lipids
Alcoholic Intoxication D000435 15 associated lipids
Tremor D014202 15 associated lipids
Encephalitis D004660 15 associated lipids
Hypertrophy D006984 16 associated lipids
Ventricular Fibrillation D014693 16 associated lipids
Liver Cirrhosis, Alcoholic D008104 17 associated lipids
Parkinson Disease, Secondary D010302 17 associated lipids
Down Syndrome D004314 18 associated lipids
Ischemia D007511 18 associated lipids
Hypothermia D007035 19 associated lipids
Cough D003371 19 associated lipids
Wounds and Injuries D014947 20 associated lipids
Ataxia D001259 20 associated lipids
Brain Edema D001929 20 associated lipids
Hyperglycemia D006943 21 associated lipids
Medulloblastoma D008527 22 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Stomach Neoplasms D013274 24 associated lipids
Hyperemia D006940 25 associated lipids
Cerebrovascular Disorders D002561 25 associated lipids
Alcoholism D000437 27 associated lipids
Brain Diseases D001927 27 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Neuralgia D009437 28 associated lipids
Insulinoma D007340 28 associated lipids
Obesity D009765 29 associated lipids
Kidney Diseases D007674 29 associated lipids
Kidney Neoplasms D007680 29 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Drug Eruptions D003875 30 associated lipids
Catalepsy D002375 30 associated lipids
Hypothyroidism D007037 32 associated lipids
Peripheral Nervous System Diseases D010523 33 associated lipids
Memory Disorders D008569 33 associated lipids
Uremia D014511 33 associated lipids
Spinal Cord Injuries D013119 34 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Hyperplasia D006965 34 associated lipids
Epilepsy D004827 35 associated lipids
Fever D005334 35 associated lipids
Nervous System Diseases D009422 37 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Adenoma D000236 40 associated lipids
Arthritis D001168 41 associated lipids
Hypotension D007022 41 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Occupational Diseases D009784 42 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 4-aminobutyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 4-aminobutyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 4-aminobutyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-aminobutyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-aminobutyric acid

Download all related citations
Per page 10 20 50 100 | Total 40318
Authors Title Published Journal PubMed Link
Luca G et al. Central and peripheral metabolic changes induced by gamma-hydroxybutyrate. 2015 Sleep pmid:25515097
Cui SQ et al. Puerarin protects against damage to spatial learning and memory ability in mice with chronic alcohol poisoning. 2015 Braz. J. Med. Biol. Res. pmid:25831201
Kardamakis AA et al. Tectal microcircuit generating visual selection commands on gaze-controlling neurons. 2015 Proc. Natl. Acad. Sci. U.S.A. pmid:25825743
Alatorre A et al. The local application of a flavonoid, (-)-epicatechin, increases the spiking of globus pallidus neurons in a dose-dependent manner and diminishes the catalepsy induced by haloperidol. 2015 Behav Pharmacol pmid:25503260
Yan X et al. Activation of toll like receptor 4 attenuates GABA synthesis and postsynaptic GABA receptor activities in the spinal dorsal horn via releasing interleukin-1 beta. 2015 J Neuroinflammation pmid:25571780
Montserrat-de la Paz S et al. Validation and additional support for an experimental animal model of fibromyalgia. 2015 Mod Rheumatol pmid:24983406
Brown AR et al. Developmentally regulated neurosteroid synthesis enhances GABAergic neurotransmission in mouse thalamocortical neurones. 2015 J. Physiol. (Lond.) pmid:25556800
Sabaliauskas N et al. Neurosteroid effects at α4βδ GABAA receptors alter spatial learning and synaptic plasticity in CA1 hippocampus across the estrous cycle of the mouse. 2015 Brain Res. pmid:25542386
Chen B et al. Cosmetic side effects of antiepileptic drugs in adults with epilepsy. 2015 Epilepsy Behav pmid:25513768
Zhang Y et al. Decreased carbon shunting from glucose toward oxidative metabolism in diet-induced ketotic rat brain. 2015 J. Neurochem. pmid:25314677