4-aminobutyric acid

4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.

Cross Reference

Introduction

To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-aminobutyric acid?

4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid

MeSH term MeSH ID Detail
Tremor D014202 15 associated lipids
Encephalitis D004660 15 associated lipids
Fetal Resorption D005327 15 associated lipids
Dyskinesia, Drug-Induced D004409 15 associated lipids
Alcoholic Intoxication D000435 15 associated lipids
Ventricular Fibrillation D014693 16 associated lipids
Hypertrophy D006984 16 associated lipids
Parkinson Disease, Secondary D010302 17 associated lipids
Liver Cirrhosis, Alcoholic D008104 17 associated lipids
Ischemia D007511 18 associated lipids
Down Syndrome D004314 18 associated lipids
Cough D003371 19 associated lipids
Hypothermia D007035 19 associated lipids
Ataxia D001259 20 associated lipids
Brain Edema D001929 20 associated lipids
Wounds and Injuries D014947 20 associated lipids
Hyperglycemia D006943 21 associated lipids
Medulloblastoma D008527 22 associated lipids
Stomach Neoplasms D013274 24 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Cerebrovascular Disorders D002561 25 associated lipids
Hyperemia D006940 25 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Alcoholism D000437 27 associated lipids
Brain Diseases D001927 27 associated lipids
Neuralgia D009437 28 associated lipids
Insulinoma D007340 28 associated lipids
Kidney Diseases D007674 29 associated lipids
Obesity D009765 29 associated lipids
Kidney Neoplasms D007680 29 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Drug Eruptions D003875 30 associated lipids
Catalepsy D002375 30 associated lipids
Hypothyroidism D007037 32 associated lipids
Uremia D014511 33 associated lipids
Memory Disorders D008569 33 associated lipids
Peripheral Nervous System Diseases D010523 33 associated lipids
Hyperplasia D006965 34 associated lipids
Spinal Cord Injuries D013119 34 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Fever D005334 35 associated lipids
Epilepsy D004827 35 associated lipids
Nervous System Diseases D009422 37 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Adenoma D000236 40 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Arthritis D001168 41 associated lipids
Hypotension D007022 41 associated lipids
Occupational Diseases D009784 42 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 4-aminobutyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 4-aminobutyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 4-aminobutyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-aminobutyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-aminobutyric acid

Download all related citations
Per page 10 20 50 100 | Total 40318
Authors Title Published Journal PubMed Link
Wang C et al. Succinic Semialdehyde Promotes Prosurvival Capability of Agrobacterium tumefaciens. 2016 J. Bacteriol. pmid:26755630
Simm B et al. Effects of prostaglandin E2 on cells cultured from the rat organum vasculosum laminae terminalis and median preoptic nucleus. 2016 Neuroscience pmid:26608124
Chinnici F et al. Discrimination of some European vinegars with protected denomination of origin as a function of their amino acid and biogenic amine content. 2016 J. Sci. Food Agric. pmid:26676828
Martin BS et al. Rescue of deficient amygdala tonic γ-aminobutyric acidergic currents in the Fmr-/y mouse model of fragile X syndrome by a novel γ-aminobutyric acid type A receptor-positive allosteric modulator. 2016 J. Neurosci. Res. pmid:26308557
Vazquez-DeRose J et al. Hypocretin/orexin antagonism enhances sleep-related adenosine and GABA neurotransmission in rat basal forebrain. 2016 Brain Struct Funct pmid:25431268
Buczynski MW et al. Diacylglycerol lipase disinhibits VTA dopamine neurons during chronic nicotine exposure. 2016 Proc. Natl. Acad. Sci. U.S.A. pmid:26755579
Volk DW and Lewis DA The Role of Endocannabinoid Signaling in Cortical Inhibitory Neuron Dysfunction in Schizophrenia. 2016 Biol. Psychiatry pmid:26210060
Groundwater PW et al. The Differential Effects of Resveratrol and trans-ε-Viniferin on the GABA-Induced Current in GABAA Receptor Subtypes Expressed in Xenopus Laevis Oocytes. 2015 J Pharm Pharm Sci pmid:26626239
Lee KH et al. Bidirectional Signaling of Neuregulin-2 Mediates Formation of GABAergic Synapses and Maturation of Glutamatergic Synapses in Newborn Granule Cells of Postnatal Hippocampus. 2015 J. Neurosci. pmid:26674872
Wang H et al. Cocaine-Induced Endocannabinoid Mobilization in the Ventral Tegmental Area. 2015 Cell Rep pmid:26365195