4-aminobutyric acid
4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
Cross Reference
Introduction
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 4-aminobutyric acid?
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
PubChem Associated disorders and diseases
What pathways are associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 4-aminobutyric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 4-aminobutyric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 4-aminobutyric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Zappettini S et al. | Presynaptic nicotinic α7 and non-α7 receptors stimulate endogenous GABA release from rat hippocampal synaptosomes through two mechanisms of action. | 2011 | PLoS ONE | pmid:21346795 |
| Conti F et al. | A Role for GAT-1 in Presynaptic GABA Homeostasis? | 2011 | Front Cell Neurosci | pmid:21503156 |
| Siggberg L et al. | Familial 6p22.2 duplication associates with mild developmental delay and increased SSADH activity. | 2011 | Am. J. Med. Genet. B Neuropsychiatr. Genet. | pmid:21438145 |
| Guo M et al. | The bZIP transcription factor MoAP1 mediates the oxidative stress response and is critical for pathogenicity of the rice blast fungus Magnaporthe oryzae. | 2011 | PLoS Pathog. | pmid:21383978 |
| Brams M et al. | A structural and mutagenic blueprint for molecular recognition of strychnine and d-tubocurarine by different cys-loop receptors. | 2011 | PLoS Biol. | pmid:21468359 |
| Görbitz CH | Solid-state phase transitions in DL-norvaline studied by single-crystal X-ray diffraction. | 2011 | J Phys Chem B | pmid:21332110 |
| Coyne L et al. | Neuropharmacological properties of neurons derived from human stem cells. | 2011 | Neurochem. Int. | pmid:21315124 |
| Yahr P | Sex difference and response to testosterone in gabaergic cells of the medial preoptic nucleus and ventral bed nuclei of the stria terminalis in gerbils. | 2011 | Horm Behav | pmid:21281643 |
| de Carvalho LP et al. | On the chemical mechanism of succinic semialdehyde dehydrogenase (GabD1) from Mycobacterium tuberculosis. | 2011 | Arch. Biochem. Biophys. | pmid:21303655 |
| Alabed S et al. | Gamma-aminobutyric acid agonists for neuroleptic-induced tardive dyskinesia. | 2011 | Cochrane Database Syst Rev | pmid:21491376 |
| Rosell A et al. | Brain perihematoma genomic profile following spontaneous human intracerebral hemorrhage. | 2011 | PLoS ONE | pmid:21311749 |
| Kanner AM | Are antiepileptic drugs used in the treatment of migraine associated with an increased risk of suicidality? | 2011 | Curr Pain Headache Rep | pmid:21479999 |
| Pizzolato R et al. | Efficacy and tolerability of pregabalin as preventive treatment for migraine: a 3-month follow-up study. | 2011 | J Headache Pain | pmid:21479703 |
| Ponnusamy K et al. | Microbial community and metabolomic comparison of irritable bowel syndrome faeces. | 2011 | J. Med. Microbiol. | pmid:21330412 |
| Singh P et al. | Transcriptomic analysis in a Drosophila model identifies previously implicated and novel pathways in the therapeutic mechanism in neuropsychiatric disorders. | 2011 | Front Neurosci | pmid:21503142 |
| Li YX et al. | Modulation of the assay system for the sensory integration of 2 sensory stimuli that inhibit each other in nematode Caenorhabditis elegans. | 2011 | Neurosci Bull | pmid:21441968 |
| Nakamura S and Ohtsubo K | Acceleration of germination of super-hard rice cultivar EM10 by soaking with red onion. | 2011 | Biosci. Biotechnol. Biochem. | pmid:21389608 |
| Beaumont M and Maccaferri G | Is connexin36 critical for GABAergic hypersynchronization in the hippocampus? | 2011 | J. Physiol. (Lond.) | pmid:21300748 |
| Wolkowitz OM et al. | Of sound mind and body: depression, disease, and accelerated aging. | 2011 | Dialogues Clin Neurosci | pmid:21485744 |
| CantarÃn-Extremera V et al. | [Clinical, electroencephalographic and genomic characteristics of patients with epilepsy with febrile seizures plus]. | 2011 | Rev Neurol | pmid:21425109 |
| Jiménez-González C et al. | Non-neuronal, slow GABA signalling in the ventrobasal thalamus targets δ-subunit-containing GABA(A) receptors. | 2011 | Eur. J. Neurosci. | pmid:21395866 |
| Kortleven C et al. | The endocannabinoid 2-arachidonoylglycerol inhibits long-term potentiation of glutamatergic synapses onto ventral tegmental area dopamine neurons in mice. | 2011 | Eur. J. Neurosci. | pmid:21410793 |
| Chu LC et al. | Chronic intrathecal infusion of gabapentin prevents nerve ligation-induced pain in rats. | 2011 | Br J Anaesth | pmid:21441243 |
| Jia P et al. | Prioritization of epilepsy associated candidate genes by convergent analysis. | 2011 | PLoS ONE | pmid:21390307 |
| El-Ansary AK et al. | Plasma fatty acids as diagnostic markers in autistic patients from Saudi Arabia. | 2011 | Lipids Health Dis | pmid:21510882 |
| Vijayalakshmi A et al. | Anticonvulsant and neurotoxicity profile of the rhizome of Smilax china Linn. in mice. | 2011 | Indian J Pharmacol | pmid:21455417 |
| Sanna E et al. | Voluntary Ethanol Consumption Induced by Social Isolation Reverses the Increase of α(4)/δ GABA(A) Receptor Gene Expression and Function in the Hippocampus of C57BL/6J Mice. | 2011 | Front Neurosci | pmid:21347217 |
| Manolakos E et al. | Combined 22q11.1-q11.21 deletion with 15q11.2-q13.3 duplication identified by array-CGH in a 6 years old boy. | 2011 | Mol Cytogenet | pmid:21345209 |
| Ha KY et al. | Pregabalin as a neuroprotector after spinal cord injury in rats: biochemical analysis and effect on glial cells. | 2011 | J. Korean Med. Sci. | pmid:21394310 |
| Kanehira T et al. | Relieving occupational fatigue by consumption of a beverage containing γ-amino butyric acid. | 2011 | J. Nutr. Sci. Vitaminol. | pmid:21512285 |
| Calderón Guzmán D et al. | Effect of flutamide and two novel synthetic steroids on GABA, glutamine and some oxidative stress markers in rat brain and prostate. | 2011 | Andrologia | pmid:21486400 |
| Flores A et al. | Acute effects of unilateral sectioning the superior ovarian nerve of rats with unilateral ovariectomy on ovarian hormones (progesterone, testosterone and estradiol) levels vary during the estrous cycle. | 2011 | Reprod. Biol. Endocrinol. | pmid:21414235 |
| Wang Z et al. | Progesterone administration modulates cortical TLR4/NF-κB signaling pathway after subarachnoid hemorrhage in male rats. | 2011 | Mediators Inflamm. | pmid:21403869 |
| Muthuraman A and Singh N | Attenuating effect of Acorus calamus extract in chronic constriction injury induced neuropathic pain in rats: an evidence of anti-oxidative, anti-inflammatory, neuroprotective and calcium inhibitory effects. | 2011 | BMC Complement Altern Med | pmid:21426568 |
| Young RL | Sensing via intestinal sweet taste pathways. | 2011 | Front Neurosci | pmid:21519398 |
| Hosoda K et al. | Cooperative adaptation to establishment of a synthetic bacterial mutualism. | 2011 | PLoS ONE | pmid:21359225 |
| Jo JY et al. | Neurosteroid modulation of benzodiazepine-sensitive GABAA tonic inhibition in supraoptic magnocellular neurons. | 2011 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:21451144 |
| Tachikawa M and Hosoya K | Transport characteristics of guanidino compounds at the blood-brain barrier and blood-cerebrospinal fluid barrier: relevance to neural disorders. | 2011 | Fluids Barriers CNS | pmid:21352605 |
| Thwaites DT and Anderson CM | The SLC36 family of proton-coupled amino acid transporters and their potential role in drug transport. | 2011 | Br. J. Pharmacol. | pmid:21501141 |
| Araújo WL et al. | Antisense inhibition of the iron-sulphur subunit of succinate dehydrogenase enhances photosynthesis and growth in tomato via an organic acid-mediated effect on stomatal aperture. | 2011 | Plant Cell | pmid:21307286 |
| Bockbrader HN et al. | Pregabalin effect on steady-state pharmacokinetics of carbamazepine, lamotrigine, phenobarbital, phenytoin, topiramate, valproate, and tiagabine. | 2011 | Epilepsia | pmid:21314678 |
| Margalit E et al. | Inner and outer retinal mechanisms engaged by epiretinal stimulation in normal and rd mice. | 2011 | Vis. Neurosci. | pmid:21463541 |
| Béracochéa D et al. | Interaction between Diazepam and Hippocampal Corticosterone after Acute Stress: Impact on Memory in Middle-Aged Mice. | 2011 | Front Behav Neurosci | pmid:21516247 |
| Dykman LA and Khlebtsov NG | Gold nanoparticles in biology and medicine: recent advances and prospects. | 2011 | Acta Naturae | pmid:22649683 |
| Yang ZZ et al. | Effect of ginkgolide B on striatal extracellular amino acids in middle cerebral artery occluded rats. | 2011 | J Ethnopharmacol | pmid:21527331 |
| Cui YF et al. | Embryonic stem cell-derived L1 overexpressing neural aggregates enhance recovery after spinal cord injury in mice. | 2011 | PLoS ONE | pmid:21445247 |
| Bonin RP et al. | Pharmacological enhancement of δ-subunit-containing GABA(A) receptors that generate a tonic inhibitory conductance in spinal neurons attenuates acute nociception in mice. | 2011 | Pain | pmid:21396779 |
| Porcu P et al. | Genetic analysis of the neurosteroid deoxycorticosterone and its relation to alcohol phenotypes: identification of QTLs and downstream gene regulation. | 2011 | PLoS ONE | pmid:21494628 |
| Zhou JQ et al. | Analyzing clinical and electrophysiological characteristics of Paroxysmal Dyskinesia. | 2011 | J Res Med Sci | pmid:21448393 |
| Yang H et al. | Comparison of metabolic profiling of cyanidin-3-O-galactoside and extracts from blueberry in aged mice. | 2011 | J. Agric. Food Chem. | pmid:21302942 |