4-aminobutyric acid

4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.

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Introduction

To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-aminobutyric acid?

4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid

MeSH term MeSH ID Detail
Epilepsy, Complex Partial D017029 1 associated lipids
Gangliosidosis, GM1 D016537 1 associated lipids
alpha-Mannosidosis D008363 1 associated lipids
Iatrogenic Disease D007049 1 associated lipids
Restless Legs Syndrome D012148 2 associated lipids
Respiratory Paralysis D012133 1 associated lipids
Illusions D007088 1 associated lipids
Mercury Poisoning D008630 4 associated lipids
Confusion D003221 4 associated lipids
Meige Syndrome D008538 1 associated lipids
Vertigo D014717 4 associated lipids
Common Bile Duct Diseases D003137 3 associated lipids
Esotropia D004948 1 associated lipids
Strabismus D013285 1 associated lipids
Somatostatinoma D013005 1 associated lipids
Pantothenate Kinase-Associated Neurodegeneration D006211 1 associated lipids
Meningitis, Aseptic D008582 1 associated lipids
Meningitis, Viral D008587 1 associated lipids
Polyradiculopathy D011128 1 associated lipids
Pituitary Diseases D010900 2 associated lipids
Primary Ovarian Insufficiency D016649 2 associated lipids
Adrenal Cortex Diseases D000303 1 associated lipids
Aphakia D001035 1 associated lipids
Newcastle Disease D009521 4 associated lipids
Opioid-Related Disorders D009293 5 associated lipids
Torticollis D014103 1 associated lipids
Causalgia D002422 1 associated lipids
Gigantism D005877 1 associated lipids
Encephalitis, Viral D018792 3 associated lipids
Varicose Veins D014648 7 associated lipids
Retrograde Degeneration D012183 4 associated lipids
Tetanus D013742 1 associated lipids
Gyrate Atrophy D015799 2 associated lipids
Carcinoma, Acinar Cell D018267 1 associated lipids
Tuberous Sclerosis D014402 2 associated lipids
Neuroendocrine Tumors D018358 4 associated lipids
Ocular Motility Disorders D015835 2 associated lipids
Dysarthria D004401 2 associated lipids
Tension-Type Headache D018781 1 associated lipids
Pain, Intractable D010148 4 associated lipids
Porphyria, Acute Intermittent D017118 3 associated lipids
Arachnoid Cysts D016080 1 associated lipids
Muscle Hypertonia D009122 1 associated lipids
Mitral Valve Prolapse D008945 1 associated lipids
Perceptual Disorders D010468 3 associated lipids
Cestode Infections D002590 3 associated lipids
Polyneuropathies D011115 3 associated lipids
Encephalomyelitis, Venezuelan Equine D004685 1 associated lipids
Retinal Artery Occlusion D015356 2 associated lipids
Congenital Disorders of Glycosylation D018981 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 4-aminobutyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 4-aminobutyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 4-aminobutyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-aminobutyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-aminobutyric acid

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Authors Title Published Journal PubMed Link
Xu Z et al. From the Cover: Functional Analysis Reveals Glutamate and Gamma-Aminobutyric Acid-Gated Chloride Channels as Targets of Avermectins in the Carmine Spider Mite. 2017 Toxicol. Sci. pmid:27742867
Turner DP et al. Using a graphical risk tool to examine willingness to take migraine prophylactic medications. 2016 Pain pmid:27820159
Smetana KS et al. Antiepileptic dosing for critically ill adult patients receiving renal replacement therapy. 2016 J Crit Care pmid:27546759
Lai EC et al. Comparative persistence of antiepileptic drugs in patients with epilepsy: A STROBE-compliant retrospective cohort study. 2016 Medicine (Baltimore) pmid:27583857
Motoyama K et al. Cholesterol-Lowering Effect of Octaarginine-Appended β-Cyclodextrin in Npc1-Trap-CHO Cells. 2016 Biol. Pharm. Bull. pmid:27601082
Setoyama D et al. Plasma Metabolites Predict Severity of Depression and Suicidal Ideation in Psychiatric Patients-A Multicenter Pilot Analysis. 2016 PLoS ONE pmid:27984586
Donvito G et al. Palmitoylethanolamide Reverses Paclitaxel-Induced Allodynia in Mice. 2016 J. Pharmacol. Exp. Ther. pmid:27608657
Kantrowitz JT et al. d-Cycloserine, an NMDA Glutamate Receptor Glycine Site Partial Agonist, Induces Acute Increases in Brain Glutamate Plus Glutamine and GABA Comparable to Ketamine. 2016 Am J Psychiatry pmid:27903101
Mettang T Uremic Itch Management. 2016 Curr. Probl. Dermatol. pmid:27578082
Dadsetan S et al. Infliximab reduces peripheral inflammation, neuroinflammation, and extracellular GABA in the cerebellum and improves learning and motor coordination in rats with hepatic encephalopathy. 2016 J Neuroinflammation pmid:27623772