4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Prelle K et al. | Endpoints of drug discovery for menopausal vasomotor symptoms: interpretation of data from a proxy of disease. | 2012 | Menopause | pmid:22473248 |
Lee KY and Gold MS | Inflammatory mediators potentiate high affinity GABA(A) currents in rat dorsal root ganglion neurons. | 2012 | Neurosci. Lett. | pmid:22580064 |
Thompson AJ et al. | The pharmacological profile of ELIC, a prokaryotic GABA-gated receptor. | 2012 | Neuropharmacology | pmid:22677470 |
Boughton BA et al. | The crystal structure of dihydrodipicolinate synthase from Escherichia coli with bound pyruvate and succinic acid semialdehyde: unambiguous resolution of the stereochemistry of the condensation product. | 2012 | Proteins | pmid:22552955 |
Ariyawardana A et al. | Use of single- and multi-drug regimens in the management of classic (idiopathic) trigeminal neuralgia: an 11-year experience at a single Sri Lankan institution. | 2012 | J Investig Clin Dent | pmid:22180190 |
Abbasi E et al. | Neuroprotective effects of vitexin, a flavonoid, on pentylenetetrazole-induced seizure in rats. | 2012 | Chem Biol Drug Des | pmid:22554436 |
Simpson SM et al. | The antidepressant phenelzine enhances memory in the double Y-maze and increases GABA levels in the hippocampus and frontal cortex of rats. | 2012 | Pharmacol. Biochem. Behav. | pmid:22503968 |
Ito S et al. | Etodolac, a cyclooxygenase-2 inhibitor, attenuates paclitaxel-induced peripheral neuropathy in a mouse model of mechanical allodynia. | 2012 | J. Pharmacol. Exp. Ther. | pmid:22460833 |
Ogawa K et al. | Pharmacological characterization of lysophosphatidic acid-induced pain with clinically relevant neuropathic pain drugs. | 2012 | Eur J Pain | pmid:22337641 |
Reese EA et al. | Gabapentin's minimal action on markers of rat brain arachidonic acid metabolism agrees with its inefficacy against bipolar disorder. | 2012 Aug-Sep | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22841517 |