4-aminobutyric acid

4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.

Cross Reference

Introduction

To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-aminobutyric acid?

4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid

MeSH term MeSH ID Detail
Intellectual Disability D008607 13 associated lipids
Glioma D005910 112 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Obesity D009765 29 associated lipids
Bradycardia D001919 13 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Genetic Diseases, Inborn D030342 4 associated lipids
Alzheimer Disease D000544 76 associated lipids
Hyperplasia D006965 34 associated lipids
Magnesium Deficiency D008275 9 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 4-aminobutyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 4-aminobutyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 4-aminobutyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-aminobutyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-aminobutyric acid

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Authors Title Published Journal PubMed Link
Gonzalez LE et al. Stimulation of benzodiazepine receptors in the dorsal hippocampus and median raphé reveals differential GABAergic control in two animal tests of anxiety. 1998 Eur. J. Neurosci. pmid:9875346
Pernberg J et al. Structure and dynamics of receptive fields in the visual cortex of the cat (area 18) and the influence of GABAergic inhibition. 1998 Eur. J. Neurosci. pmid:9875339
Wickelgren I Drug may suppress the craving for nicotine. 1998 Science pmid:9874627
Czupryn A et al. Neurotransmitter system markers in adult barrel field. 1998 Somatosens Mot Res pmid:9874522
Kogo M et al. Examination of the relationships between jaw opener and closer rhythmical muscle activity in an in vitro brainstem jaw-attached preparation. 1998 Somatosens Mot Res pmid:9874519
Bonanno G et al. GABA(B) receptors as potential targets for drugs able to prevent excessive excitatory amino acid transmission in the spinal cord. 1998 Eur. J. Pharmacol. pmid:9874164
McGraw T and Stacey BR Gabapentin for treatment of neuropathic pain in a 12-year-old girl. 1998 Clin J Pain pmid:9874016
Carruthers NI et al. Synthesis of a series of sulfinic acid analogs of GABA and evaluation of their GABAB receptor affinities. 1998 Bioorg. Med. Chem. Lett. pmid:9873676
Serfass L and Casara PJ General synthesis of 3-substituted alkenyl GABA as potential anticonvulsants. 1998 Bioorg. Med. Chem. Lett. pmid:9873588
Bernstein EM and Quick MW Regulation of gamma-aminobutyric acid (GABA) transporters by extracellular GABA. 1999 J. Biol. Chem. pmid:9873028