4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Subramanian P et al. | Temporal oscillations of phosphatases in N-phthaloyl gamma-aminobutyric acid treated rats. | 1998 | Indian J. Exp. Biol. | pmid:10085783 |
Seidl JJ and Slawson JG | Gabapentin for painful diabetic neuropathy. | 1999 | J Fam Pract | pmid:10086757 |
Mozrzymas JW et al. | Chlorpromazine inhibits miniature GABAergic currents by reducing the binding and by increasing the unbinding rate of GABAA receptors. | 1999 | J. Neurosci. | pmid:10087062 |
Verheugen JA et al. | Noninvasive measurements of the membrane potential and GABAergic action in hippocampal interneurons. | 1999 | J. Neurosci. | pmid:10087068 |
Polgár E et al. | GABAergic neurons that contain neuropeptide Y selectively target cells with the neurokinin 1 receptor in laminae III and IV of the rat spinal cord. | 1999 | J. Neurosci. | pmid:10087077 |
Alkondon M et al. | Choline and selective antagonists identify two subtypes of nicotinic acetylcholine receptors that modulate GABA release from CA1 interneurons in rat hippocampal slices. | 1999 | J. Neurosci. | pmid:10087082 |
Brussaard AB et al. | Changes in properties and neurosteroid regulation of GABAergic synapses in the supraoptic nucleus during the mammalian female reproductive cycle. | 1999 | J. Physiol. (Lond.) | pmid:10087349 |
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Rogers HJ and Lietman PS | Inhibition by trimethoprim of some effects of epidermal growth factor on human fibroblasts in tissue culture. | 1976 | Biochem. Pharmacol. | pmid:1008900 |
Möck M et al. | GABAergic inhibition in the rat pontine nuclei is exclusively extrinsic: evidence from an in situ hybridization study for GAD67 mRNA. | 1999 | Exp Brain Res | pmid:10090666 |