4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Frye MA et al. | Possible gabapentin-induced thyroiditis. | 1999 | J Clin Psychopharmacol | pmid:9934948 |
Galenko-IaroshevskiÄ PA et al. | [Effect of the gamma-aminobutyric acid derivative, TZ-50-2, on the systemic and cardiac hemodynamics, and the size of myocardial necrosis area]. | 1998 | Biull Eksp Biol Med | pmid:9934514 |
Mameli O et al. | Epileptic discharge of cortical, subcortical and spinal neurons in penicillin induced experimental epilepsy. | 1999 | Arch Ital Biol | pmid:9934432 |
Martin R et al. | Cognitive effects of topiramate, gabapentin, and lamotrigine in healthy young adults. | 1999 | Neurology | pmid:9932951 |
Pombal MA et al. | Cholinergic and GABAergic neuronal elements in the pineal organ of lampreys, and tract-tracing observations of differential connections of pinealofugal neurons. | 1999 | Cell Tissue Res. | pmid:9931367 |
Rhee JS et al. | Calcium channels in the GABAergic presynaptic nerve terminals projecting to meynert neurons of the rat. | 1999 | J. Neurochem. | pmid:9930756 |
Rivera C et al. | The K+/Cl- co-transporter KCC2 renders GABA hyperpolarizing during neuronal maturation. | 1999 | Nature | pmid:9930699 |
Miles R | Neurobiology. A homeostatic switch. | 1999 | Nature | pmid:9930694 |
Tömböl T et al. | Electron microscopic data on the neurons of nuclei subpretectalis and posterior-ventralis thalami. A combined immunohistochemical study. | 1999 | Anat. Embryol. | pmid:9930623 |
Hyde JC and Robinson N | Electron cytochemical localization of gamma-aminobutyric acid catabolism in rat cerebellar cortex. | 1976 | Histochemistry | pmid:993062 |