4-aminobutyric acid

4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.

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Introduction

To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-aminobutyric acid?

4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid

MeSH term MeSH ID Detail
Dandy-Walker Syndrome D003616 1 associated lipids
Hypophosphatasia D007014 1 associated lipids
Tooth Abnormalities D014071 1 associated lipids
Neck Pain D019547 2 associated lipids
Exanthema D005076 11 associated lipids
Neuroaxonal Dystrophies D019150 3 associated lipids
Syringomyelia D013595 1 associated lipids
Neuroectodermal Tumors, Primitive D018242 1 associated lipids
Reflex Sympathetic Dystrophy D012019 4 associated lipids
Angelman Syndrome D017204 1 associated lipids
Prader-Willi Syndrome D011218 2 associated lipids
Diplopia D004172 2 associated lipids
Low Back Pain D017116 2 associated lipids
Myofascial Pain Syndromes D009209 1 associated lipids
Serotonin Syndrome D020230 1 associated lipids
Hiccup D006606 1 associated lipids
Vision, Low D015354 1 associated lipids
Hemifacial Spasm D019569 1 associated lipids
Choristoma D002828 1 associated lipids
Cranial Nerve Diseases D003389 1 associated lipids
Postpoliomyelitis Syndrome D016262 1 associated lipids
Earache D004433 2 associated lipids
Melkersson-Rosenthal Syndrome D008556 2 associated lipids
Tongue, Fissured D014063 1 associated lipids
Hypernatremia D006955 1 associated lipids
Phantom Limb D010591 1 associated lipids
Arachnoiditis D001100 1 associated lipids
Paraparesis D020335 1 associated lipids
Gangliosidoses, GM2 D020143 1 associated lipids
Nervous System Malformations D009421 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 4-aminobutyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 4-aminobutyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 4-aminobutyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-aminobutyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-aminobutyric acid

Download all related citations
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Authors Title Published Journal PubMed Link
Summa M et al. Presynaptic mGlu7 receptors control GABA release in mouse hippocampus. 2013 Neuropharmacology pmid:22564442
de Souza LM and Franci CR Differential immunoreactivity of glucocorticoid receptor and GABA in GABAergic afferents to parvocellular neurons in the paraventricular nucleus. 2013 Neurosci. Lett. pmid:23276637
Anneken JH et al. MDMA increases glutamate release and reduces parvalbumin-positive GABAergic cells in the dorsal hippocampus of the rat: role of cyclooxygenase. 2013 J Neuroimmune Pharmacol pmid:23179355
Egashira N et al. Effects of mood stabilizers on marble-burying behavior in mice: involvement of GABAergic system. 2013 Psychopharmacology (Berl.) pmid:23086022
Han B et al. Quantitative LC-MS/MS analysis of arachidonoyl amino acids in mouse brain with treatment of FAAH inhibitor. 2013 Anal. Biochem. pmid:23044255
Rajak H et al. Novel limonene and citral based 2,5-disubstituted-1,3,4-oxadiazoles: a natural product coupled approach to semicarbazones for antiepileptic activity. 2013 Bioorg. Med. Chem. Lett. pmid:23265873
Shamsi Meymandi M and Keyhanfar F Relative potency of pregabalin, gabapentin, and morphine in a mouse model of visceral pain. 2013 Can J Anaesth pmid:23132044
Siebel AM et al. Antiepileptic drugs prevent changes in adenosine deamination during acute seizure episodes in adult zebrafish. 2013 Pharmacol. Biochem. Behav. pmid:23287800
Vanelderen P et al. Effects of chronic administration of amitriptyline, gabapentin and minocycline on spinal brain-derived neurotrophic factor expression and neuropathic pain behavior in a rat chronic constriction injury model. 2013 Mar-Apr Reg Anesth Pain Med pmid:23337936
Gassel M et al. The novel isoxazoline ectoparasiticide fluralaner: selective inhibition of arthropod γ-aminobutyric acid- and L-glutamate-gated chloride channels and insecticidal/acaricidal activity. 2014 Insect Biochem. Mol. Biol. pmid:24365472