4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Sawaya MC et al. | Effects of anticonvulsant drugs on the cerebral enzymes metabolizing GABA. | 1975 | Epilepsia | pmid:9890792 |
de Toffol B et al. | [Anticonvulsants can aggravate idiopathic generalized epilepsy]. | 1998 | Rev. Neurol. (Paris) | pmid:9894288 |
van der Knaap MS et al. | D-2-Hydroxyglutaric aciduria: biochemical marker or clinical disease entity? | 1999 | Ann. Neurol. | pmid:9894884 |
Arimatsu Y et al. | Cerebral cortical specification by early potential restriction of progenitor cells and later phenotype control of postmitotic neurons. | 1999 | Development | pmid:9895311 |
Meldrum B et al. | [Pharmacologic approach to Papio papio photosensitive epilepsy]. | 1978 | Actual Pharmacol (Paris) | pmid:98965 |
Kääriäinen I | Effects of aminooxyacetic acid and baclofen on the catalepsy and on the increase of mesolimbic and striatal dopamine turnover induced by haloperidol in rats. | 1976 | Acta Pharmacol Toxicol (Copenh) | pmid:989685 |
Kääriäinen K and Vikberg P | Effects of aminooxyacetic acid and baclofen on catalepsy, striatal homovanillic acid increase and antinociception caused by methadone in rats. | 1976 | Acta Pharmacol Toxicol (Copenh) | pmid:990037 |
Henningsson S and Rosengren E | The effect of nandrolone, an anabolic steroid on putrescine metabolism in the mouse. | 1976 | Br. J. Pharmacol. | pmid:990594 |
Waddington JL and Crow TJ | A behavioural model of the GABA-facilitating action of benzodiazepines: rotational behaviour after unilateral intranigral injection of chloridiazepoxide [proceedings]. | 1976 | Br. J. Pharmacol. | pmid:990631 |
Koob G et al. | The behavioural effects of EOS-induced changes in substantia nigra GABA levels [proceedings]. | 1976 | Br. J. Pharmacol. | pmid:990632 |